paracetamol-3025 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the paracetamol-3025 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AASS aminoadipate-semialdehyde synthase
ADCY10 adenylate cyclase 10 (soluble)
AGTR1 angiotensin II receptor, type 1
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ARC activity-regulated cytoskeleton-associated protein
AREG amphiregulin
ARTN artemin
ASCL1 achaete-scute family bHLH transcription factor 1
ATP10B ATPase, class V, type 10B
BTF3P11 basic transcription factor 3 pseudogene 11
C11ORF16 chromosome 11 open reading frame 16
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CHGA chromogranin A
CLDN3 claudin 3
CORO2B coronin, actin binding protein, 2B
CRABP2 cellular retinoic acid binding protein 2
CRISP2 cysteine-rich secretory protein 2
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DAPK2 death-associated protein kinase 2
DFNB31 deafness, autosomal recessive 31
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EPB41 erythrocyte membrane protein band 4.1
EYA3 EYA transcriptional coactivator and phosphatase 3
EYA4 EYA transcriptional coactivator and phosphatase 4
FCAR Fc fragment of IgA receptor
FRMD4A FERM domain containing 4A
GPR135 G protein-coupled receptor 135
GPR35 G protein-coupled receptor 35
GRIA3 glutamate receptor, ionotropic, AMPA 3
HGD homogentisate 1,2-dioxygenase
HNMT histamine N-methyltransferase
HOXB1 homeobox B1
HOXD13 homeobox D13
HPSE2 heparanase 2 (inactive)
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HTR7P1 5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1
IL36RN interleukin 36 receptor antagonist
IL4 interleukin 4
IMPG1 interphotoreceptor matrix proteoglycan 1
INPP5J inositol polyphosphate-5-phosphatase J
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIAA1045 KIAA1045
KIF1A kinesin family member 1A
KLHL22 kelch-like family member 22
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LRP1 low density lipoprotein receptor-related protein 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MATN2 matrilin 2
MBL2 mannose-binding lectin (protein C) 2, soluble
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPY neuropeptide Y
NRG1 neuregulin 1
NRP1 neuropilin 1
PALLD palladin, cytoskeletal associated protein
PAX8 paired box 8
PBOV1 prostate and breast cancer overexpressed 1
PCDHB17P protocadherin beta 17 pseudogene
PKP3 plakophilin 3
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PPP1R3A protein phosphatase 1, regulatory subunit 3A
PRDM12 PR domain containing 12
PRDM9 PR domain containing 9
RBBP4 retinoblastoma binding protein 4
RDH8 retinol dehydrogenase 8 (all-trans)
RFPL1 ret finger protein-like 1
RIBC2 RIB43A domain with coiled-coils 2
RNF122 ring finger protein 122
RPS6 ribosomal protein S6
RTP4 receptor (chemosensory) transporter protein 4
RUNDC3A RUN domain containing 3A
SAMD4A sterile alpha motif domain containing 4A
SCGB2A1 secretoglobin, family 2A, member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SH2D3A SH2 domain containing 3A
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC17A4 solute carrier family 17, member 4
SPARCL1 SPARC-like 1 (hevin)
SPATA2L spermatogenesis associated 2-like
SPINK5 serine peptidase inhibitor, Kazal type 5
SRPK3 SRSF protein kinase 3
SRPX2 sushi-repeat containing protein, X-linked 2
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TRO trophinin
TRPC7 transient receptor potential cation channel, subfamily C, member 7
TSHR thyroid stimulating hormone receptor
ZNF702P zinc finger protein 702, pseudogene

decreased expression

Symbol Name
ACPP acid phosphatase, prostate
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AHDC1 AT hook, DNA binding motif, containing 1
AMT aminomethyltransferase
ANKRD55 ankyrin repeat domain 55
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
BCL2L2 BCL2-like 2
C11ORF30 chromosome 11 open reading frame 30
C17ORF53 chromosome 17 open reading frame 53
C1ORF159 chromosome 1 open reading frame 159
C1QTNF3 C1q and tumor necrosis factor related protein 3
C9ORF3 chromosome 9 open reading frame 3
C9ORF9 chromosome 9 open reading frame 9
C9ORF91 chromosome 9 open reading frame 91
CD300C CD300c molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CFAP69 cilia and flagella associated protein 69
CLCN5 chloride channel, voltage-sensitive 5
CLGN calmegin
CTAGE9 CTAGE family, member 9
DCAF13 DDB1 and CUL4 associated factor 13
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
FAM118A family with sequence similarity 118, member A
FAM160B2 family with sequence similarity 160, member B2
FAM53B family with sequence similarity 53, member B
FBXL7 F-box and leucine-rich repeat protein 7
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FER fer (fps/fes related) tyrosine kinase
FMOD fibromodulin
FRS3 fibroblast growth factor receptor substrate 3
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GBP2 guanylate binding protein 2, interferon-inducible
GID4 GID complex subunit 4
GJA1 gap junction protein, alpha 1, 43kDa
GLTP glycolipid transfer protein
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GNG7 guanine nucleotide binding protein (G protein), gamma 7
HIST1H1B histone cluster 1, H1b
HIST1H4E histone cluster 1, H4e
IBSP integrin-binding sialoprotein
IFNA14 interferon, alpha 14
INCENP inner centromere protein antigens 135/155kDa
KIF23 kinesin family member 23
KRT31 keratin 31, type I
LIG4 ligase IV, DNA, ATP-dependent
LRP5 low density lipoprotein receptor-related protein 5
MAGEH1 melanoma antigen family H1
MCOLN1 mucolipin 1
MDM4 MDM4, p53 regulator
NCKAP1L NCK-associated protein 1-like
NEK11 NIMA-related kinase 11
NINJ2 ninjurin 2
NIPAL2 NIPA-like domain containing 2
NOL10 nucleolar protein 10
NOTCH1 notch 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PARP11 poly (ADP-ribose) polymerase family, member 11
PDLIM2 PDZ and LIM domain 2 (mystique)
PER3 period circadian clock 3
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
PPAN peter pan homolog (Drosophila)
PRAF2 PRA1 domain family, member 2
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
RAB17 RAB17, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RGS13 regulator of G-protein signaling 13
RPL23AP32 ribosomal protein L23a pseudogene 32
SCN10A sodium channel, voltage gated, type X alpha subunit
SERTAD3 SERTA domain containing 3
SGMS1 sphingomyelin synthase 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC16A4 solute carrier family 16, member 4
SLC17A2 solute carrier family 17, member 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC35F6 solute carrier family 35, member F6
SLITRK5 SLIT and NTRK-like family, member 5
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SSBP3 single stranded DNA binding protein 3
TCTA T-cell leukemia translocation altered
TESK1 testis-specific kinase 1
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THBS4 thrombospondin 4
TLR6 toll-like receptor 6
TONSL tonsoku-like, DNA repair protein
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TSC22D4 TSC22 domain family, member 4
TUBA3C tubulin, alpha 3c
YY2 YY2 transcription factor
ZNF155 zinc finger protein 155
ZNF749 zinc finger protein 749
ZNF768 zinc finger protein 768
ZNF813 zinc finger protein 813