papaverine-1755 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the papaverine-1755 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ACOX3 acyl-CoA oxidase 3, pristanoyl
ADORA1 adenosine A1 receptor
ANAPC2 anaphase promoting complex subunit 2
ARHGAP32 Rho GTPase activating protein 32
ARL4C ADP-ribosylation factor-like 4C
ARRB2 arrestin, beta 2
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ASB13 ankyrin repeat and SOCS box containing 13
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
AXL AXL receptor tyrosine kinase
BEX1 brain expressed, X-linked 1
BMP6 bone morphogenetic protein 6
C11ORF71 chromosome 11 open reading frame 71
C19ORF66 chromosome 19 open reading frame 66
CACFD1 calcium channel flower domain containing 1
CD38 CD38 molecule
CEP164 centrosomal protein 164kDa
CFLAR CASP8 and FADD-like apoptosis regulator
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CNTFR ciliary neurotrophic factor receptor
CREM cAMP responsive element modulator
CSNK1D casein kinase 1, delta
DNASE1L1 deoxyribonuclease I-like 1
DOCK4 dedicator of cytokinesis 4
DST dystonin
DUSP4 dual specificity phosphatase 4
ELF4 E74-like factor 4 (ets domain transcription factor)
EMD emerin
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
FLRT2 fibronectin leucine rich transmembrane protein 2
FNBP1 formin binding protein 1
FTH1 ferritin, heavy polypeptide 1
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
FUCA1 fucosidase, alpha-L- 1, tissue
FUZ fuzzy planar cell polarity protein
GAB2 GRB2-associated binding protein 2
GABARAPL1 GABA(A) receptor-associated protein like 1
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GNG7 guanine nucleotide binding protein (G protein), gamma 7
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HOMER1 homer scaffolding protein 1
IFITM3 interferon induced transmembrane protein 3
KIAA0195 KIAA0195
KIFC3 kinesin family member C3
KLHL21 kelch-like family member 21
KYNU kynureninase
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LPCAT1 lysophosphatidylcholine acyltransferase 1
LUZP1 leucine zipper protein 1
MAGED2 melanoma antigen family D2
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MCTP2 multiple C2 domains, transmembrane 2
MPPE1 metallophosphoesterase 1
MT1E metallothionein 1E
MT1H metallothionein 1H
MT2A metallothionein 2A
MX2 MX dynamin-like GTPase 2
MYL10 myosin, light chain 10, regulatory
NQO2 NAD(P)H dehydrogenase, quinone 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
OGFR opioid growth factor receptor
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PALM paralemmin
PARG poly (ADP-ribose) glycohydrolase
PDE4B phosphodiesterase 4B, cAMP-specific
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLSCR1 phospholipid scramblase 1
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
QDPR quinoid dihydropteridine reductase
RBMS3 RNA binding motif, single stranded interacting protein 3
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RITA1 RBPJ interacting and tubulin associated 1
SAG S-antigen; retina and pineal gland (arrestin)
SAT1 spermidine/spermine N1-acetyltransferase 1
SATB1 SATB homeobox 1
SDC2 syndecan 2
SGPL1 sphingosine-1-phosphate lyase 1
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SMG5 SMG5 nonsense mediated mRNA decay factor
SPDEF SAM pointed domain containing ETS transcription factor
SSBP2 single-stranded DNA binding protein 2
STAT1 signal transducer and activator of transcription 1, 91kDa
TBX6 T-box 6
THBS1 thrombospondin 1
THBS4 thrombospondin 4
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNK1 tyrosine kinase, non-receptor, 1
USF2 upstream transcription factor 2, c-fos interacting
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WIPI1 WD repeat domain, phosphoinositide interacting 1
WNT16 wingless-type MMTV integration site family, member 16
YIPF2 Yip1 domain family, member 2

decreased expression

Symbol Name
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
ALAS1 5'-aminolevulinate synthase 1
ARID4A AT rich interactive domain 4A (RBP1-like)
ATF3 activating transcription factor 3
ATXN2 ataxin 2
BCL10 B-cell CLL/lymphoma 10
BIN2 bridging integrator 2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C3AR1 complement component 3a receptor 1
CCDC47 coiled-coil domain containing 47
CCL2 chemokine (C-C motif) ligand 2
CD14 CD14 molecule
CD302 CD302 molecule
CD69 CD69 molecule
CD9 CD9 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CHSY1 chondroitin sulfate synthase 1
CISH cytokine inducible SH2-containing protein
CLEC7A C-type lectin domain family 7, member A
CXCL8 chemokine (C-X-C motif) ligand 8
CYTIP cytohesin 1 interacting protein
DCPS decapping enzyme, scavenger
DDIT4 DNA-damage-inducible transcript 4
DHCR24 24-dehydrocholesterol reductase
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DPH2 DPH2 homolog (S. cerevisiae)
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ENDOG endonuclease G
ENO2 enolase 2 (gamma, neuronal)
EPS8 epidermal growth factor receptor pathway substrate 8
F3 coagulation factor III (thromboplastin, tissue factor)
FAM216A family with sequence similarity 216, member A
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GADD45A growth arrest and DNA-damage-inducible, alpha
GARS glycyl-tRNA synthetase
GLRX5 glutaredoxin 5
GPRC5C G protein-coupled receptor, class C, group 5, member C
HCAR3 hydroxycarboxylic acid receptor 3
HIRA histone cell cycle regulator
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPA13 heat shock protein 70kDa family, member 13
HSPB1 heat shock 27kDa protein 1
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
INSIG2 insulin induced gene 2
KDM3A lysine (K)-specific demethylase 3A
KIF21B kinesin family member 21B
LACTB2 lactamase, beta 2
LBR lamin B receptor
LOC642236 FSHD region gene 1 pseudogene
LTB lymphotoxin beta (TNF superfamily, member 3)
MCRS1 microspherule protein 1
MICB MHC class I polypeptide-related sequence B
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MSMO1 methylsterol monooxygenase 1
MYLIP myosin regulatory light chain interacting protein
NDRG1 N-myc downstream regulated 1
NUP93 nucleoporin 93kDa
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PARP16 poly (ADP-ribose) polymerase family, member 16
PDGFC platelet derived growth factor C
PFKP phosphofructokinase, platelet
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLCD1 phospholipase C, delta 1
PSAT1 phosphoserine aminotransferase 1
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTER phosphotriesterase related
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RGS13 regulator of G-protein signaling 13
RGS16 regulator of G-protein signaling 16
RPL39L ribosomal protein L39-like
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC38A1 solute carrier family 38, member 1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SPON2 spondin 2, extracellular matrix protein
SPP1 secreted phosphoprotein 1
SQLE squalene epoxidase
SUN2 Sad1 and UNC84 domain containing 2
THOC6 THO complex 6
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM45A transmembrane protein 45A
TNF tumor necrosis factor
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TPBG trophoblast glycoprotein
TRIB3 tribbles pseudokinase 3
TRIM8 tripartite motif containing 8
TXNIP thioredoxin interacting protein
WDR12 WD repeat domain 12
ZNF395 zinc finger protein 395