pantothenate kinase-associated neurodegeneration Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A neurodegenerative disease that is characterized by an abnormal accumulation of iron in the brain and progressive degeneration of the nervous system. (Human Disease Ontology, DOID_3981)
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Genes

55 genes co-occuring with the disease pantothenate kinase-associated neurodegeneration in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PANK2 pantothenate kinase 2 3.83248
PANK1 pantothenate kinase 1 2.72301
C19ORF12 chromosome 19 open reading frame 12 1.99039
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 1.86735
FA2H fatty acid 2-hydroxylase 1.65879
PANK3 pantothenate kinase 3 1.42147
JPH3 junctophilin 3 1.38123
PANK4 pantothenate kinase 4 1.30663
ATP13A2 ATPase type 13A2 1.27955
FTL ferritin, light polypeptide 1.18927
FOXN4 forkhead box N4 1.1009
IREB2 iron-responsive element binding protein 2 1.03451
COASY CoA synthase 1.03114
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) 1.02566
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 1.01174
FTH1 ferritin, heavy polypeptide 1 1.00837
URI1 URI1, prefoldin-like chaperone 0.994017
CP ceruloplasmin (ferroxidase) 0.990644
WDR45 WD repeat domain 45 0.9898
FTMT ferritin mitochondrial 0.95369
DCAF17 DDB1 and CUL4 associated factor 17 0.822077
CDO1 cysteine dioxygenase type 1 0.750864
GJC2 gap junction protein, gamma 2, 47kDa 0.740705
AGK acylglycerol kinase 0.720461
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 0.6939
FXN frataxin 0.660008
THAP1 THAP domain containing, apoptosis associated protein 1 0.658026
IGKV1-17 immunoglobulin kappa variable 1-17 0.651298
TFR2 transferrin receptor 2 0.626888
DLAT dihydrolipoamide S-acetyltransferase 0.621008
PLA2G1B phospholipase A2, group IB (pancreas) 0.609666
GCH1 GTP cyclohydrolase 1 0.605762
FBXO7 F-box protein 7 0.580828
RPGRIP1L RPGRIP1-like 0.547032
SPG11 spastic paraplegia 11 (autosomal recessive) 0.538118
HEPH hephaestin 0.52536
LPIN1 lipin 1 0.521888
KEL Kell blood group, metallo-endopeptidase 0.511112
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.499614
ALAS2 5'-aminolevulinate synthase 2 0.428891
TAZ tafazzin 0.416896
SNCB synuclein, beta 0.407919
HFE hemochromatosis 0.404184
PNPLA6 patatin-like phospholipase domain containing 6 0.388166
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 0.368888
SNCG synuclein, gamma (breast cancer-specific protein 1) 0.36187
GAN gigaxonin 0.32009
CHKA choline kinase alpha 0.301976
HTT huntingtin 0.297651
HFE2 hemochromatosis type 2 (juvenile) 0.292616
HAMP hepcidin antimicrobial peptide 0.290821
TBP TATA box binding protein 0.250311
TF transferrin 0.185612
HMOX1 heme oxygenase 1 0.18472
FABP3 fatty acid binding protein 3, muscle and heart 0.173571