panic disorder Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description An anxiety disorder that is characterized by unexpected and repeated episodes of intense fear accompanied by physical symptoms that may include chest pain, heart palpitations, shortness of breath, dizziness, or abdominal distress. (Human Disease Ontology, DOID_594)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:594
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Genes

44 genes associated with the disease panic disorder in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
ANO2 anoctamin 2, calcium activated chloride channel 1.46277
SGCZ sarcoglycan, zeta 1.41627
TMEM132D transmembrane protein 132D 1.34849
PKP1 plakophilin 1 1.34719
PEPD peptidase D 1.29251
SDK2 sidekick cell adhesion molecule 2 1.28906
CALCOCO1 calcium binding and coiled-coil domain 1 1.26953
PRDM11 PR domain containing 11 1.26904
GRM7 glutamate receptor, metabotropic 7 1.14463
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 1.04846
CTNNA2 catenin (cadherin-associated protein), alpha 2 1.03835
TLR1 toll-like receptor 1 1.02778
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.99638
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) 0.969215
PRDM16 PR domain containing 16 0.965779
FHIT fragile histidine triad 0.958374
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.958374
STON2 stonin 2 0.916706
TMEM132B transmembrane protein 132B 0.890183
LRP1B low density lipoprotein receptor-related protein 1B 0.88338
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 0.860976
RBM23 RNA binding motif protein 23 0.824363
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.795282
ANOS1 anosmin 1 0.788564
FCRL1 Fc receptor-like 1 0.783797
ARHGEF26-AS1 ARHGEF26 antisense RNA 1 0.780738
ACVR2A activin A receptor, type IIA 0.774598
WWTR1 WW domain containing transcription regulator 1 0.751629
LOC339298 uncharacterized LOC339298 0.73777
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) 0.736879
DTNA dystrobrevin, alpha 0.734781
MAN2A1 mannosidase, alpha, class 2A, member 1 0.732392
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.7253
PRKD3 protein kinase D3 0.718224
ZFYVE26 zinc finger, FYVE domain containing 26 0.707377
PDZRN4 PDZ domain containing ring finger 4 0.699793
ARHGAP21 Rho GTPase activating protein 21 0.695208
PREP prolyl endopeptidase 0.689868
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.688304
JAG1 jagged 1 0.676587
PTRH2 peptidyl-tRNA hydrolase 2 0.670361
CNTN4 contactin 4 0.669646
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.668836
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.560918