pancuronium bromide-7329 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the pancuronium bromide-7329 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AMACR alpha-methylacyl-CoA racemase
APAF1 apoptotic peptidase activating factor 1
AUTS2 autism susceptibility candidate 2
C11ORF63 chromosome 11 open reading frame 63
C1ORF61 chromosome 1 open reading frame 61
CACFD1 calcium channel flower domain containing 1
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CARD14 caspase recruitment domain family, member 14
CASKIN2 CASK interacting protein 2
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CDRT1 CMT1A duplicated region transcript 1
CNOT4 CCR4-NOT transcription complex, subunit 4
CSF1R colony stimulating factor 1 receptor
DIAPH2 diaphanous-related formin 2
DPYSL4 dihydropyrimidinase-like 4
DSCAM Down syndrome cell adhesion molecule
E2F4 E2F transcription factor 4, p107/p130-binding
EFNA3 ephrin-A3
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
ELP6 elongator acetyltransferase complex subunit 6
EMID1 EMI domain containing 1
EPHA1 EPH receptor A1
FBXO41 F-box protein 41
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPR22 G protein-coupled receptor 22
GRIK5 glutamate receptor, ionotropic, kainate 5
GSTA3 glutathione S-transferase alpha 3
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H3I histone cluster 1, H3i
HPS1 Hermansky-Pudlak syndrome 1
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IL22 interleukin 22
ING4 inhibitor of growth family, member 4
IQCC IQ motif containing C
IRS2 insulin receptor substrate 2
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
LZTFL1 leucine zipper transcription factor-like 1
MAGOH2P mago-nashi homolog 2, pseudogene
MAP1A microtubule-associated protein 1A
MAP2K5 mitogen-activated protein kinase kinase 5
MBD3 methyl-CpG binding domain protein 3
MEF2D myocyte enhancer factor 2D
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MUC1 mucin 1, cell surface associated
NF2 neurofibromin 2 (merlin)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NME5 NME/NM23 family member 5
OVOL2 ovo-like zinc finger 2
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
PARD6A par-6 family cell polarity regulator alpha
PAX5 paired box 5
PCDHGA1 protocadherin gamma subfamily A, 1
PCNX pecanex homolog (Drosophila)
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE4B phosphodiesterase 4B, cAMP-specific
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PPAP2B phosphatidic acid phosphatase type 2B
PRF1 perforin 1 (pore forming protein)
PRKG2 protein kinase, cGMP-dependent, type II
PSCA prostate stem cell antigen
RABGAP1L RAB GTPase activating protein 1-like
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGS12 regulator of G-protein signaling 12
SCAPER S-phase cyclin A-associated protein in the ER
SCN10A sodium channel, voltage gated, type X alpha subunit
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEC24D SEC24 family member D
SIGLEC7 sialic acid binding Ig-like lectin 7
SIK2 salt-inducible kinase 2
SIVA1 SIVA1, apoptosis-inducing factor
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC43A3 solute carrier family 43, member 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SMAD1 SMAD family member 1
STMN1 stathmin 1
STS steroid sulfatase (microsomal), isozyme S
TADA3 transcriptional adaptor 3
TAPBP TAP binding protein (tapasin)
TBC1D22A TBC1 domain family, member 22A
TGFB2 transforming growth factor, beta 2
THRAP3 thyroid hormone receptor associated protein 3
TOP3B topoisomerase (DNA) III beta
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPAN9 tetraspanin 9
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
ZIM2 zinc finger, imprinted 2
ZNF224 zinc finger protein 224
ZNF286A zinc finger protein 286A
ZNF696 zinc finger protein 696
ZNF710 zinc finger protein 710
ZNRD1-AS1 ZNRD1 antisense RNA 1

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ANKRD36 ankyrin repeat domain 36
ANXA2P3 annexin A2 pseudogene 3
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BAG4 BCL2-associated athanogene 4
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BCORL1 BCL6 corepressor-like 1
BMP4 bone morphogenetic protein 4
C11ORF80 chromosome 11 open reading frame 80
C14ORF132 chromosome 14 open reading frame 132
C7ORF43 chromosome 7 open reading frame 43
CAMTA1 calmodulin binding transcription activator 1
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CEMIP cell migration inducing protein, hyaluronan binding
CHKB choline kinase beta
CPNE1 copine I
CTC1 CTS telomere maintenance complex component 1
CTH cystathionine gamma-lyase
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCAF13 DDB1 and CUL4 associated factor 13
DDIT3 DNA-damage-inducible transcript 3
DET1 de-etiolated homolog 1 (Arabidopsis)
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DOCK1 dedicator of cytokinesis 1
EFHD2 EF-hand domain family, member D2
ETAA1 Ewing tumor-associated antigen 1
FBRS fibrosin
FBXO31 F-box protein 31
FKBP10 FK506 binding protein 10, 65 kDa
FRS2 fibroblast growth factor receptor substrate 2
FSTL3 follistatin-like 3 (secreted glycoprotein)
GLB1L2 galactosidase, beta 1-like 2
GPC3 glypican 3
GPX2 glutathione peroxidase 2
GRTP1 growth hormone regulated TBC protein 1
HIST1H2AI histone cluster 1, H2ai
HIST2H2AA3 histone cluster 2, H2aa3
HPS6 Hermansky-Pudlak syndrome 6
HSPA2 heat shock 70kDa protein 2
ICK intestinal cell (MAK-like) kinase
IFITM1 interferon induced transmembrane protein 1
IL15RA interleukin 15 receptor, alpha
IL17RA interleukin 17 receptor A
IMPACT impact RWD domain protein
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF6 interferon regulatory factor 6
KIAA0513 KIAA0513
LIN7B lin-7 homolog B (C. elegans)
MANBA mannosidase, beta A, lysosomal
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MORC3 MORC family CW-type zinc finger 3
MTERF4 mitochondrial transcription termination factor 4
MTRF1 mitochondrial translational release factor 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NDE1 nudE neurodevelopment protein 1
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OLFML2A olfactomedin-like 2A
PACS1 phosphofurin acidic cluster sorting protein 1
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PARPBP PARP1 binding protein
PCDHB8 protocadherin beta 8
PGP phosphoglycolate phosphatase
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLD3 phospholipase D family, member 3
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPAP2 RNA polymerase II associated protein 2
RPH3AL rabphilin 3A-like (without C2 domains)
SDC3 syndecan 3
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SH2D4A SH2 domain containing 4A
SLC41A3 solute carrier family 41, member 3
STBD1 starch binding domain 1
STX5 syntaxin 5
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAGLN transgelin
TBCCD1 TBCC domain containing 1
TCTN1 tectonic family member 1
TMEM254 transmembrane protein 254
TPCN1 two pore segment channel 1
TRIM5 tripartite motif containing 5
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TUBA3C tubulin, alpha 3c
USP6NL USP6 N-terminal like
VAV1 vav 1 guanine nucleotide exchange factor
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZDHHC13 zinc finger, DHHC-type containing 13
ZNF141 zinc finger protein 141
ZNF212 zinc finger protein 212
ZNF227 zinc finger protein 227
ZNF623 zinc finger protein 623
ZNF665 zinc finger protein 665
ZSCAN5A zinc finger and SCAN domain containing 5A