pancuronium bromide-4570 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the pancuronium bromide-4570 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSM3 acyl-CoA synthetase medium-chain family member 3
ADCY9 adenylate cyclase 9
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ANGPT4 angiopoietin 4
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
BAAT bile acid CoA:amino acid N-acyltransferase
BCL2 B-cell CLL/lymphoma 2
BMP7 bone morphogenetic protein 7
C1QTNF3 C1q and tumor necrosis factor related protein 3
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CDC14B cell division cycle 14B
CDKL3 cyclin-dependent kinase-like 3
CERS4 ceramide synthase 4
CLUAP1 clusterin associated protein 1
COL16A1 collagen, type XVI, alpha 1
COMMD4 COMM domain containing 4
CYSLTR1 cysteinyl leukotriene receptor 1
DGKE diacylglycerol kinase, epsilon 64kDa
DKFZP434C153 DKFZP434C153 protein
DOK4 docking protein 4
ESRRG estrogen-related receptor gamma
FAM134B family with sequence similarity 134, member B
FBXO11 F-box protein 11
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FLT4 fms-related tyrosine kinase 4
GAB1 GRB2-associated binding protein 1
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GPR85 G protein-coupled receptor 85
HAO2 hydroxyacid oxidase 2 (long chain)
HIST1H2AL histone cluster 1, H2al
HMHB1 histocompatibility (minor) HB-1
HOXB2 homeobox B2
HOXB6 homeobox B6
HSPA12A heat shock 70kDa protein 12A
IL5RA interleukin 5 receptor, alpha
IQCC IQ motif containing C
JAG1 jagged 1
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KDM4C lysine (K)-specific demethylase 4C
KRIT1 KRIT1, ankyrin repeat containing
LOC100294391 uncharacterized LOC100294391
LRRK1 leucine-rich repeat kinase 1
LTBP4 latent transforming growth factor beta binding protein 4
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MED16 mediator complex subunit 16
MEFV Mediterranean fever
MSR1 macrophage scavenger receptor 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NOP16 NOP16 nucleolar protein
NSUN6 NOP2/Sun domain family, member 6
NUP54 nucleoporin 54kDa
OLFML2B olfactomedin-like 2B
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PBX2 pre-B-cell leukemia homeobox 2
PCDHGB6 protocadherin gamma subfamily B, 6
PDE4D phosphodiesterase 4D, cAMP-specific
PDE4DIP phosphodiesterase 4D interacting protein
PHF14 PHD finger protein 14
PITX1 paired-like homeodomain 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
PRAF2 PRA1 domain family, member 2
PRDM14 PR domain containing 14
PRKCE protein kinase C, epsilon
PRUNE prune exopolyphosphatase
PSD4 pleckstrin and Sec7 domain containing 4
PVT1 Pvt1 oncogene (non-protein coding)
RALYL RALY RNA binding protein-like
RASA3 RAS p21 protein activator 3
RASAL2 RAS protein activator like 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RIBC2 RIB43A domain with coiled-coils 2
RPL10 ribosomal protein L10
SCN11A sodium channel, voltage gated, type XI alpha subunit
SELL selectin L
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SETD1A SET domain containing 1A
SH2D3A SH2 domain containing 3A
SLC19A3 solute carrier family 19 (thiamine transporter), member 3
SLC35F6 solute carrier family 35, member F6
SNAP25 synaptosomal-associated protein, 25kDa
SOGA1 suppressor of glucose, autophagy associated 1
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
STS steroid sulfatase (microsomal), isozyme S
TAS2R10 taste receptor, type 2, member 10
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TCP10 t-complex 10
TK2 thymidine kinase 2, mitochondrial
TMOD1 tropomodulin 1
TSNAXIP1 translin-associated factor X interacting protein 1
TTC9 tetratricopeptide repeat domain 9
USP22 ubiquitin specific peptidase 22
ZC2HC1C zinc finger, C2HC-type containing 1C
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF44 zinc finger protein 44
ZNF550 zinc finger protein 550
ZNF639 zinc finger protein 639
ZNF674 zinc finger protein 674

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALPK1 alpha-kinase 1
ANXA2P1 annexin A2 pseudogene 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARL14 ADP-ribosylation factor-like 14
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BAHD1 bromo adjacent homology domain containing 1
BNC1 basonuclin 1
C17ORF53 chromosome 17 open reading frame 53
C1QTNF1 C1q and tumor necrosis factor related protein 1
C9ORF40 chromosome 9 open reading frame 40
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDIP1 cell death-inducing p53 target 1
CES3 carboxylesterase 3
CHM choroideremia (Rab escort protein 1)
CLCN5 chloride channel, voltage-sensitive 5
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CNTNAP1 contactin associated protein 1
CORT cortistatin
CPNE7 copine VII
CPZ carboxypeptidase Z
DAGLA diacylglycerol lipase, alpha
DCAF4 DDB1 and CUL4 associated factor 4
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAH7 dynein, axonemal, heavy chain 7
EDIL3 EGF-like repeats and discoidin I-like domains 3
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ELSPBP1 epididymal sperm binding protein 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EVPL envoplakin
FBXO31 F-box protein 31
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FKBP1B FK506 binding protein 1B, 12.6 kDa
GAL3ST4 galactose-3-O-sulfotransferase 4
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H1D histone cluster 1, H1d
HIST1H2BM histone cluster 1, H2bm
HIST1H3A histone cluster 1, H3a
HIST1H4A histone cluster 1, H4a
HLA-DMA major histocompatibility complex, class II, DM alpha
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXA1 homeobox A1
HOXA2 homeobox A2
HOXC4 homeobox C4
HSPA1L heat shock 70kDa protein 1-like
IFI6 interferon, alpha-inducible protein 6
KIF13B kinesin family member 13B
LIG4 ligase IV, DNA, ATP-dependent
LMNB1 lamin B1
LOC100287590 uncharacterized LOC100287590
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
LY6D lymphocyte antigen 6 complex, locus D
LYRM9 LYR motif containing 9
MAGEA6 melanoma antigen family A6
MEGF8 multiple EGF-like-domains 8
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MYBBP1A MYB binding protein (P160) 1a
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
ODF2 outer dense fiber of sperm tails 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PDE12 phosphodiesterase 12
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PID1 phosphotyrosine interaction domain containing 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PROX1 prospero homeobox 1
PRSS53 protease, serine, 53
PTK7 protein tyrosine kinase 7 (inactive)
R3HCC1L R3H domain and coiled-coil containing 1-like
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RNF126P1 ring finger protein 126 pseudogene 1
RNF39 ring finger protein 39
SAMD9 sterile alpha motif domain containing 9
SCD5 stearoyl-CoA desaturase 5
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
TIGD6 tigger transposable element derived 6
TMEM212 transmembrane protein 212
TUBA3C tubulin, alpha 3c
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
ZBTB22 zinc finger and BTB domain containing 22
ZBTB39 zinc finger and BTB domain containing 39
ZNF334 zinc finger protein 334
ZNF510 zinc finger protein 510
ZNF675 zinc finger protein 675
ZNF76 zinc finger protein 76