pancuronium bromide-4393 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the pancuronium bromide-4393 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ARHGAP4 Rho GTPase activating protein 4
ASCL1 achaete-scute family bHLH transcription factor 1
ASIC1 acid sensing (proton gated) ion channel 1
ATP10B ATPase, class V, type 10B
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
B9D1 B9 protein domain 1
BAIAP3 BAI1-associated protein 3
BHMT2 betaine--homocysteine S-methyltransferase 2
C1QB complement component 1, q subcomponent, B chain
C4BPA complement component 4 binding protein, alpha
CD1A CD1a molecule
CD248 CD248 molecule, endosialin
CDO1 cysteine dioxygenase type 1
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CLCN1 chloride channel, voltage-sensitive 1
CLEC4E C-type lectin domain family 4, member E
CPEB1 cytoplasmic polyadenylation element binding protein 1
CRAT carnitine O-acetyltransferase
CSHL1 chorionic somatomammotropin hormone-like 1
CST4 cystatin S
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTSZ cathepsin Z
DNALI1 dynein, axonemal, light intermediate chain 1
ECE1 endothelin converting enzyme 1
EDA ectodysplasin A
EFR3B EFR3 homolog B (S. cerevisiae)
EGR3 early growth response 3
EMP3 epithelial membrane protein 3
EMX1 empty spiracles homeobox 1
ERO1LB ERO1-like beta (S. cerevisiae)
FAM106A family with sequence similarity 106, member A
FAP fibroblast activation protein, alpha
FGF23 fibroblast growth factor 23
FOXP3 forkhead box P3
GPR15 G protein-coupled receptor 15
GPR37L1 G protein-coupled receptor 37 like 1
GRIK5 glutamate receptor, ionotropic, kainate 5
GRM1 glutamate receptor, metabotropic 1
GRM7 glutamate receptor, metabotropic 7
GSN-AS1 GSN antisense RNA 1
HBP1 HMG-box transcription factor 1
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HEXIM1 hexamethylene bis-acetamide inducible 1
HFE hemochromatosis
HOXA1 homeobox A1
HPCAL4 hippocalcin like 4
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICAM5 intercellular adhesion molecule 5, telencephalin
IFNA16 interferon, alpha 16
IL2RB interleukin 2 receptor, beta
IRF8 interferon regulatory factor 8
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNK10 potassium channel, two pore domain subfamily K, member 10
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KLF13 Kruppel-like factor 13
KLHL35 kelch-like family member 35
KRT85 keratin 85, type II
LOC100286895 cell division cycle 27 homolog pseudogene
MAL mal, T-cell differentiation protein
MALL mal, T-cell differentiation protein-like
MUC4 mucin 4, cell surface associated
MUC8 mucin 8
NF1 neurofibromin 1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
PCDH12 protocadherin 12
PLAC4 placenta-specific 4
PLAT plasminogen activator, tissue
PLK3 polo-like kinase 3
POFUT2 protein O-fucosyltransferase 2
PTPRB protein tyrosine phosphatase, receptor type, B
RASL11B RAS-like, family 11, member B
RETN resistin
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RPS4Y1 ribosomal protein S4, Y-linked 1
SAMD9 sterile alpha motif domain containing 9
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SNAP25 synaptosomal-associated protein, 25kDa
SOAT2 sterol O-acyltransferase 2
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
TGM2 transglutaminase 2
TMPRSS4 transmembrane protease, serine 4
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TPP1 tripeptidyl peptidase I
TSC22D2 TSC22 domain family, member 2
TTC39A tetratricopeptide repeat domain 39A
WAS Wiskott-Aldrich syndrome
WNT16 wingless-type MMTV integration site family, member 16
WNT6 wingless-type MMTV integration site family, member 6
ZNF236 zinc finger protein 236
ZNF423 zinc finger protein 423

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ALOX15 arachidonate 15-lipoxygenase
ARC activity-regulated cytoskeleton-associated protein
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMC4 armadillo repeat containing 4
BAX BCL2-associated X protein
C1ORF105 chromosome 1 open reading frame 105
C2ORF54 chromosome 2 open reading frame 54
CASD1 CAS1 domain containing 1
CBX8 chromobox homolog 8
CCDC25 coiled-coil domain containing 25
CCDC9 coiled-coil domain containing 9
CEP97 centrosomal protein 97kDa
CHKB choline kinase beta
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CSF1R colony stimulating factor 1 receptor
CUZD1 CUB and zona pellucida-like domains 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DPY19L1P1 DPY19L1 pseudogene 1
DTX4 deltex 4, E3 ubiquitin ligase
EFHD2 EF-hand domain family, member D2
F3 coagulation factor III (thromboplastin, tissue factor)
FA2H fatty acid 2-hydroxylase
FAM131A family with sequence similarity 131, member A
FBXL8 F-box and leucine-rich repeat protein 8
FKBP5 FK506 binding protein 5
GPR143 G protein-coupled receptor 143
GPR27 G protein-coupled receptor 27
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HHAT hedgehog acyltransferase
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HLA-DMA major histocompatibility complex, class II, DM alpha
HMOX1 heme oxygenase 1
HOXC13 homeobox C13
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IL12RB1 interleukin 12 receptor, beta 1
IL4R interleukin 4 receptor
INO80D INO80 complex subunit D
IQSEC2 IQ motif and Sec7 domain 2
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRT24 keratin 24, type I
LHX6 LIM homeobox 6
LIN7A lin-7 homolog A (C. elegans)
LMNB1 lamin B1
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC157562 uncharacterized LOC157562
LTBP2 latent transforming growth factor beta binding protein 2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
METTL16 methyltransferase like 16
MUC3A mucin 3A, cell surface associated
MX2 MX dynamin-like GTPase 2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NKX3-2 NK3 homeobox 2
NPFFR1 neuropeptide FF receptor 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PP14571 uncharacterized LOC100130449
PROS1 protein S (alpha)
PRR14L proline rich 14-like
PRR4 proline rich 4 (lacrimal)
PTK6 protein tyrosine kinase 6
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF126P1 ring finger protein 126 pseudogene 1
RNF43 ring finger protein 43
RPL10L ribosomal protein L10-like
RUFY2 RUN and FYVE domain containing 2
SAA4 serum amyloid A4, constitutive
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SP1 Sp1 transcription factor
SRD5A3 steroid 5 alpha-reductase 3
SRPX sushi-repeat containing protein, X-linked
STK16 serine/threonine kinase 16
SYNE2 spectrin repeat containing, nuclear envelope 2
SYT17 synaptotagmin XVII
THOP1 thimet oligopeptidase 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM183A transmembrane protein 183A
TMEM209 transmembrane protein 209
TPSG1 tryptase gamma 1
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TSC22D4 TSC22 domain family, member 4
VASH2 vasohibin 2
VEGFC vascular endothelial growth factor C
VIPR1 vasoactive intestinal peptide receptor 1
WDR33 WD repeat domain 33
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF16 zinc finger protein 16
ZNF532 zinc finger protein 532
ZNF675 zinc finger protein 675
ZW10 zw10 kinetochore protein