pancreatic neoplasms Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
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Genes

141 genes associated with the disease pancreatic neoplasms in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
AMER1 APC membrane recruitment protein 1
ANKRD12 ankyrin repeat domain 12
APC adenomatous polyposis coli
APTX aprataxin
ATM ATM serine/threonine kinase
ATP13A4 ATPase type 13A4
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATR ATR serine/threonine kinase
AVEN apoptosis, caspase activation inhibitor
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BCAR1 breast cancer anti-estrogen resistance 1
BICD1 bicaudal D homolog 1 (Drosophila)
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CAB39L calcium binding protein 39-like
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like)
CDC73 cell division cycle 73
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CLPTM1L CLPTM1-like
CSF1R colony stimulating factor 1 receptor
CTIF CBP80/20-dependent translation initiation factor
CTNNA2 catenin (cadherin-associated protein), alpha 2
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAPK3 death-associated protein kinase 3
DCP1B decapping mRNA 1B
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DPP6 dipeptidyl-peptidase 6
EGFR epidermal growth factor receptor
EMILIN2 elastin microfibril interfacer 2
EML6 echinoderm microtubule associated protein like 6
EPHA3 EPH receptor A3
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC2 excision repair cross-complementation group 2
FAM149A family with sequence similarity 149, member A
FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FLT3 fms-related tyrosine kinase 3
FNBP1L formin binding protein 1-like
GATA1 GATA binding protein 1 (globin transcription factor 1)
GNAS GNAS complex locus
GUCY2F guanylate cyclase 2F, retinal
HNF1A HNF1 homeobox A
HNF4G hepatocyte nuclear factor 4, gamma
HRAS Harvey rat sarcoma viral oncogene homolog
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IL17F interleukin 17F
IL1B interleukin 1, beta
IMPG2 interphotoreceptor matrix proteoglycan 2
JAK2 Janus kinase 2
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8
KIAA1217 KIAA1217
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRAS Kirsten rat sarcoma viral oncogene homolog
L3MBTL4 l(3)mbt-like 4 (Drosophila)
LIG3 ligase III, DNA, ATP-dependent
LIG4 ligase IV, DNA, ATP-dependent
LPAR1 lysophosphatidic acid receptor 1
LPIN2 lipin 2
MAP2K4 mitogen-activated protein kinase kinase 4
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MEF2BNB-MEF2B MEF2BNB-MEF2B readthrough
MEN1 multiple endocrine neoplasia I
MET MET proto-oncogene, receptor tyrosine kinase
MGST2 microsomal glutathione S-transferase 2
MLH1 mutL homolog 1
MPL MPL proto-oncogene, thrombopoietin receptor
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MYO1D myosin ID
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NOTCH1 notch 1
NR5A2 nuclear receptor subfamily 5, group A, member 2
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NXPH1 neurexophilin 1
OGG1 8-oxoguanine DNA glycosylase
PALLD palladin, cytoskeletal associated protein
PARK2 parkin RBR E3 ubiquitin protein ligase
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
POC1B POC1 centriolar protein B
POLB polymerase (DNA directed), beta
PPARG peroxisome proliferator-activated receptor gamma
PRB2 proline-rich protein BstNI subfamily 2
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKCA protein kinase C, alpha
PTCH1 patched 1
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRT protein tyrosine phosphatase, receptor type, T
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAD54L RAD54-like (S. cerevisiae)
RB1 retinoblastoma 1
RECQL RecQ helicase-like
RET ret proto-oncogene
RNF149 ring finger protein 149
RNF43 ring finger protein 43
RUNX1 runt-related transcription factor 1
SGMS1 sphingomyelin synthase 1
SIM1 single-minded family bHLH transcription factor 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMO smoothened, frizzled class receptor
SMOC1 SPARC related modular calcium binding 1
SMTN smoothelin
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
STK11 serine/threonine kinase 11
SUGCT succinyl-CoA:glutarate-CoA transferase
SYNDIG1 synapse differentiation inducing 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TMEM213 transmembrane protein 213
TP53 tumor protein p53
TP63 tumor protein p63
TSHR thyroid stimulating hormone receptor
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WT1 Wilms tumor 1
XPA xeroderma pigmentosum, complementation group A
XPC xeroderma pigmentosum, complementation group C
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF831 zinc finger protein 831