pancreatic islet Gene Set

Dataset TISSUES Experimental Tissue Protein Expression Evidence Scores
Category proteomics
Type tissue
Description Irregular microscopic structures scattered throughout the pancreas and comprising its endocrine part (the endocrine pancreas). In humans, they are composed of at least four types of cells: the alpha cells, which secrete glucagon; the beta cells, which are the most abundant and secrete insulin; the delta cells, which secrete somatostatin; and the PP cells, which secrete pancreatic polypeptide. Degeneration of the beta cells, whose secretion (insulin) is important in carbohydrate metabolism, is the major cause of type I diabetes mellitus. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000991)
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Genes

114 proteins highly expressed in the tissue pancreatic islet in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
INS insulin 1.0758
REG1A regenerating islet-derived 1 alpha 1.0758
RPL30 ribosomal protein L30 0.766457
REG3A regenerating islet-derived 3 alpha 0.766457
EEF2 eukaryotic translation elongation factor 2 0.766457
RPS13 ribosomal protein S13 0.766457
RPS11 ribosomal protein S11 0.766457
RPS16 ribosomal protein S16 0.766457
RPS15 ribosomal protein S15 0.766457
RPS19 ribosomal protein S19 0.766457
RPS18 ribosomal protein S18 0.766457
EIF4A2 eukaryotic translation initiation factor 4A2 0.766457
TMSB4XP8 thymosin beta 4, X-linked pseudogene 8 0.766457
RPS26P6 ribosomal protein S26 pseudogene 6 0.766457
REG3G regenerating islet-derived 3 gamma 0.766457
RPL36A ribosomal protein L36a 0.766457
RPL41 ribosomal protein L41 0.766457
RPL27A ribosomal protein L27a 0.766457
OLFM4 olfactomedin 4 0.766457
CHGA chromogranin A 0.766457
CHGB chromogranin B 0.766457
RPLP1 ribosomal protein, large, P1 0.766457
RPLP0 ribosomal protein, large, P0 0.766457
NUP210L nucleoporin 210kDa-like 0.766457
SPINK1 serine peptidase inhibitor, Kazal type 1 0.766457
RPS15A ribosomal protein S15a 0.766457
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.766457
SCG5 secretogranin V 0.766457
RPL14 ribosomal protein L14 0.766457
RPL17 ribosomal protein L17 0.766457
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 0.766457
USP48 ubiquitin specific peptidase 48 0.766457
RPS7 ribosomal protein S7 0.766457
RPS6 ribosomal protein S6 0.766457
RPS5 ribosomal protein S5 0.766457
RPS9 ribosomal protein S9 0.766457
RPS8 ribosomal protein S8 0.766457
RPL28 ribosomal protein L28 0.766457
RPL24 ribosomal protein L24 0.766457
RPL27 ribosomal protein L27 0.766457
AMY1A amylase, alpha 1A (salivary) 0.766457
TPT1 tumor protein, translationally-controlled 1 0.766457
GCG glucagon 0.766457
TTR transthyretin 0.766457
RPL11 ribosomal protein L11 0.766457
RPL19 ribosomal protein L19 0.766457
SAT1 spermidine/spermine N1-acetyltransferase 1 0.766457
PLEKHA7 pleckstrin homology domain containing, family A member 7 0.766457
IAPP islet amyloid polypeptide 0.766457
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 0.766457
AMY2A amylase, alpha 2A (pancreatic) 0.766457
AMY2B amylase, alpha 2B (pancreatic) 0.766457
CELA2A chymotrypsin-like elastase family, member 2A 0.766457
C3 complement component 3 0.766457
RPS27A ribosomal protein S27a 0.766457
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.766457
RPL10A ribosomal protein L10a 0.766457
RPL32 ribosomal protein L32 0.766457
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.766457
RPS28 ribosomal protein S28 0.766457
RPS29 ribosomal protein S29 0.766457
TMSB4X thymosin beta 4, X-linked 0.766457
SSR4 signal sequence receptor, delta 0.766457
CPA2 carboxypeptidase A2 (pancreatic) 0.766457
RPL8 ribosomal protein L8 0.766457
RPL9 ribosomal protein L9 0.766457
RPL6 ribosomal protein L6 0.766457
RPL4 ribosomal protein L4 0.766457
RPL5 ribosomal protein L5 0.766457
LCN2 lipocalin 2 0.766457
GLTSCR2 glioma tumor suppressor candidate region gene 2 0.766457
RPS21 ribosomal protein S21 0.766457
RPS23 ribosomal protein S23 0.766457
RPL17P9 ribosomal protein L17 pseudogene 9 0.766457
REG1B regenerating islet-derived 1 beta 0.766457
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.766457
PNLIP pancreatic lipase 0.766457
CPA1 carboxypeptidase A1 (pancreatic) 0.766457
CEL carboxyl ester lipase 0.766457
SST somatostatin 0.766457
RPL37A ribosomal protein L37a 0.766457
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.766457
RPS26 ribosomal protein S26 0.766457
RPS24 ribosomal protein S24 0.766457
RPS25 ribosomal protein S25 0.766457
PRSS1 protease, serine, 1 (trypsin 1) 0.766457
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 0.766457
CTRB2 chymotrypsinogen B2 0.766457
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.766457
RPL37 ribosomal protein L37 0.766457
P4HB prolyl 4-hydroxylase, beta polypeptide 0.766457
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.766457
EIF1 eukaryotic translation initiation factor 1 0.766457
RPS3A ribosomal protein S3A 0.766457
CPB1 carboxypeptidase B1 (tissue) 0.766457
CD63 CD63 molecule 0.766457
SPP1 secreted phosphoprotein 1 0.766457
RPL39 ribosomal protein L39 0.766457
RPL34 ribosomal protein L34 0.766457
EEF1B2 eukaryotic translation elongation factor 1 beta 2 0.766457
PLA2G1B phospholipase A2, group IB (pancreas) 0.766457
FTH1 ferritin, heavy polypeptide 1 0.766457
GP2 glycoprotein 2 (zymogen granule membrane) 0.766457
B2M beta-2-microglobulin 0.766457
CLPS colipase, pancreatic 0.766457
CPE carboxypeptidase E 0.766457
CELA2B chymotrypsin-like elastase family, member 2B 0.766457
TMSB10 thymosin beta 10 0.766457
UBB ubiquitin B 0.766457
UBC ubiquitin C 0.766457
PPY pancreatic polypeptide 0.766457
LONP1 lon peptidase 1, mitochondrial 0.766457
EIF3L eukaryotic translation initiation factor 3, subunit L 0.766457
RPL35 ribosomal protein L35 0.766457