pancreatic cancer Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description An endocrine gland cancer located_in the pancreas. (Human Disease Ontology, DOID_1793)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:1793
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Genes

100 genes associated with the disease pancreatic cancer in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 3.99483
FUT2 fucosyltransferase 2 (secretor status included) 3.51446
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 3.08092
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 2.40544
COL18A1 collagen, type XVIII, alpha 1 2.08574
FAM3B family with sequence similarity 3, member B 2.07237
RASIP1 Ras interacting protein 1 1.99432
AFP alpha-fetoprotein 1.93944
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 1.78856
DBP D site of albumin promoter (albumin D-box) binding protein 1.76717
SEC1P secretory blood group 1, pseudogene 1.76045
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 1.7256
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 1.69848
RPL18 ribosomal protein L18 1.65109
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 1.64472
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 1.58623
FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5 1.57556
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 1.57556
NR5A2 nuclear receptor subfamily 5, group A, member 2 1.55738
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 1.53704
IL17F interleukin 17F 1.37327
MAP1A microtubule-associated protein 1A 1.35898
CA11 carbonic anhydrase XI 1.35121
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 1.34633
TP53BP1 tumor protein p53 binding protein 1 1.33817
SBF2 SET binding factor 2 1.29575
BICD1 bicaudal D homolog 1 (Drosophila) 1.26953
CLPTM1L CLPTM1-like 1.25944
LDLRAD4 low density lipoprotein receptor class A domain containing 4 1.23034
PRB2 proline-rich protein BstNI subfamily 2 1.19386
DAPK1 death-associated protein kinase 1 1.19386
DEC1 deleted in esophageal cancer 1 1.14463
GRID1 glutamate receptor, ionotropic, delta 1 1.10764
RNF149 ring finger protein 149 1.07599
LPIN2 lipin 2 1.02614
MYO1D myosin ID 1.02476
BCAR1 breast cancer anti-estrogen resistance 1 1.01084
SMTN smoothelin 1.00577
PARK2 parkin RBR E3 ubiquitin protein ligase 1.00407
DGKH diacylglycerol kinase, eta 0.990911
RNF43 ring finger protein 43 0.986376
DCP1B decapping mRNA 1B 0.986376
CAMK4 calcium/calmodulin-dependent protein kinase IV 0.983782
HNF1A HNF1 homeobox A 0.977576
PVT1 Pvt1 oncogene (non-protein coding) 0.976083
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa 0.971169
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.96514
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 0.933664
ERO1LB ERO1-like beta (S. cerevisiae) 0.931899
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 0.830304
WWOX WW domain containing oxidoreductase 0.82519
ANKRD12 ankyrin repeat domain 12 0.82192
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like) 0.820324
SUGCT succinyl-CoA:glutarate-CoA transferase 0.807358
IMPG2 interphotoreceptor matrix proteoglycan 2 0.797032
SGMS1 sphingomyelin synthase 1 0.78889
FAM149A family with sequence similarity 149, member A 0.787916
SYNDIG1 synapse differentiation inducing 1 0.784108
RUNX2 runt-related transcription factor 2 0.779242
SIM1 single-minded family bHLH transcription factor 1 0.778355
MGST2 microsomal glutathione S-transferase 2 0.776893
ASTN2 astrotactin 2 0.766699
POC1B POC1 centriolar protein B 0.755798
NXPH1 neurexophilin 1 0.752915
L3MBTL4 l(3)mbt-like 4 (Drosophila) 0.741181
EMILIN2 elastin microfibril interfacer 2 0.739575
AVEN apoptosis, caspase activation inhibitor 0.735265
KIAA1217 KIAA1217 0.728674
HNF4G hepatocyte nuclear factor 4, gamma 0.704784
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.702075
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 0.69756
CAB39L calcium binding protein 39-like 0.694217
UBASH3B ubiquitin associated and SH3 domain containing B 0.691138
TP63 tumor protein p63 0.686763
EML6 echinoderm microtubule associated protein like 6 0.68661
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.680678
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8 0.677839
FNBP1L formin binding protein 1-like 0.674129
SMOC1 SPARC related modular calcium binding 1 0.669849
LPAR1 lysophosphatidic acid receptor 1 0.669544
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.655831
ZNF831 zinc finger protein 831 0.650844
APTX aprataxin 0.642063
TMEM213 transmembrane protein 213 0.641015
CTIF CBP80/20-dependent translation initiation factor 0.639985
PRKCA protein kinase C, alpha 0.636511
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) 0.636511
ATP13A4 ATPase type 13A4 0.630986
MEF2BNB MEF2B neighbor 0.627673
BAZ2B bromodomain adjacent to zinc finger domain, 2B 0.617086
SLC22A18 solute carrier family 22, member 18 0.615118
IGSF21 immunoglobin superfamily, member 21 0.615118
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.586345
DSCAM Down syndrome cell adhesion molecule 0.586345
NRG3 neuregulin 3 0.586345
IQSEC1 IQ motif and Sec7 domain 1 0.586345
DFNB31 deafness, autosomal recessive 31 0.547225
ACSM1 acyl-CoA synthetase medium-chain family member 1 0.547225
KCNK10 potassium channel, two pore domain subfamily K, member 10 0.520364
LIN7C lin-7 homolog C (C. elegans) 0.510061