pancreatic beta cell Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description One of the cells that compose the bulk of the islets of Langerhans and secrete insulin. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000783)
Similar Terms
Downloads & Tools

Genes

740 proteins co-occuring with the tissue pancreatic beta cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
INS insulin 4.79674
GCG glucagon 3.31428
IAPP islet amyloid polypeptide 3.02573
GCK glucokinase (hexokinase 4) 2.94191
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 2.89268
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 2.76117
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 2.68635
FOXM1 forkhead box M1 2.57141
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 2.38181
GIP gastric inhibitory polypeptide 2.38067
PDX1 pancreatic and duodenal homeobox 1 2.22408
DPP4 dipeptidyl-peptidase 4 2.21351
HMX1 H6 family homeobox 1 2.20665
PAX4 paired box 4 2.1655
NEUROG3 neurogenin 3 2.11179
LAD1 ladinin 1 2.10165
NIT1 nitrilase 1 2.09364
GLP1R glucagon-like peptide 1 receptor 2.08082
IRS2 insulin receptor substrate 2 2.06691
HNF1A HNF1 homeobox A 2.06477
SST somatostatin 2.04391
NEUROD1 neuronal differentiation 1 1.99056
IL1B interleukin 1, beta 1.92841
INSR insulin receptor 1.91902
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 1.90758
SLC30A8 solute carrier family 30 (zinc transporter), member 8 1.88425
MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A 1.88063
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.86978
PPY pancreatic polypeptide 1.85482
PTPRN protein tyrosine phosphatase, receptor type, N 1.79195
FFAR1 free fatty acid receptor 1 1.75874
G6PC2 glucose-6-phosphatase, catalytic, 2 1.72484
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 1.70793
BTC betacellulin 1.69599
NKX2-2 NK2 homeobox 2 1.68703
LEP leptin 1.68503
TCF7 transcription factor 7 (T-cell specific, HMG-box) 1.64807
IRS1 insulin receptor substrate 1 1.58338
WFS1 Wolfram syndrome 1 (wolframin) 1.56086
HNF1B HNF1 homeobox B 1.5594
HNF4A hepatocyte nuclear factor 4, alpha 1.55795
SYTL4 synaptotagmin-like 4 1.55746
CD4 CD4 molecule 1.55746
NKX6-1 NK6 homeobox 1 1.55552
GIPR gastric inhibitory polypeptide receptor 1.54922
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 1.51617
CAPN10 calpain 10 1.50291
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.46355
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 1.44265
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 1.42876
ISL1 ISL LIM homeobox 1 1.41676
HK1 hexokinase 1 1.40846
IGF1 insulin-like growth factor 1 (somatomedin C) 1.40386
PTPN3 protein tyrosine phosphatase, non-receptor type 3 1.40156
INSM2 insulinoma-associated 2 1.35813
FOXA2 forkhead box A2 1.35313
FOXO1 forkhead box O1 1.33093
GCKR glucokinase (hexokinase 4) regulator 1.32506
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.32325
HHEX hematopoietically expressed homeobox 1.3192
PPARG peroxisome proliferator-activated receptor gamma 1.31063
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 1.31063
GJD2 gap junction protein, delta 2, 36kDa 1.30343
STX1A syntaxin 1A (brain) 1.27964
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 1.2671
TNF tumor necrosis factor 1.24253
PC pyruvate carboxylase 1.24163
TRAC T cell receptor alpha constant 1.23762
MTNR1B melatonin receptor 1B 1.23584
NSF N-ethylmaleimide-sensitive factor 1.22425
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 1.22336
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.22202
PAX6 paired box 6 1.20111
VPREB1 pre-B lymphocyte 1 1.20111
PCSK1 proprotein convertase subtilisin/kexin type 1 1.19845
GCGR glucagon receptor 1.19356
MNX1 motor neuron and pancreas homeobox 1 1.19045
GHRL ghrelin/obestatin prepropeptide 1.18334
TXNIP thioredoxin interacting protein 1.18068
CPE carboxypeptidase E 1.16116
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 1.15939
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.14697
SOD2 superoxide dismutase 2, mitochondrial 1.14564
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.14432
DDIT3 DNA-damage-inducible transcript 3 1.13811
RAB27A RAB27A, member RAS oncogene family 1.13767
LEPR leptin receptor 1.12438
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.12128
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 1.11774
RAB3A RAB3A, member RAS oncogene family 1.1142
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 1.11199
NNT nicotinamide nucleotide transhydrogenase 1.10756
GLIS3 GLIS family zinc finger 3 1.10579
GPR119 G protein-coupled receptor 119 1.10093
PTPRD protein tyrosine phosphatase, receptor type, D 1.10048
PTPN12 protein tyrosine phosphatase, non-receptor type 12 1.09827
FAM3B family with sequence similarity 3, member B 1.0912
HLA-B major histocompatibility complex, class I, B 1.08722
FASLG Fas ligand (TNF superfamily, member 6) 1.08501
TMEM27 transmembrane protein 27 1.08501
RETN resistin 1.06559
ADCY2 adenylate cyclase 2 (brain) 1.06515
DNAH8 dynein, axonemal, heavy chain 8 1.05677
JUN jun proto-oncogene 1.0462
CCND2 cyclin D2 1.03522
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.03302
ENSA endosulfine alpha 1.03214
PTF1A pancreas specific transcription factor, 1a 1.02381
C2CD4B C2 calcium-dependent domain containing 4B 1.02294
CAT catalase 1.01768
SLC30A10 solute carrier family 30, member 10 1.01593
KRT19 keratin 19, type I 1.01462
PPARA peroxisome proliferator-activated receptor alpha 1.01331
HLA-C major histocompatibility complex, class I, C 1.01112
XBP1 X-box binding protein 1 1.00763
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 1.00458
ICA1 islet cell autoantigen 1, 69kDa 1.0024
ATF6 activating transcription factor 6 0.998908
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 0.998473
PCSK2 proprotein convertase subtilisin/kexin type 2 0.996731
STXBP1 syntaxin binding protein 1 0.994989
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.991509
PASK PAS domain containing serine/threonine kinase 0.990204
CDC123 cell division cycle 123 0.975449
ERN1 endoplasmic reticulum to nucleus signaling 1 0.975015
RPH3A rabphilin 3A 0.970686
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.970253
MAPK8 mitogen-activated protein kinase 8 0.968523
PKLR pyruvate kinase, liver and RBC 0.963335
SYT7 synaptotagmin VII 0.962903
GAST gastrin 0.962471
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.960744
GPX1 glutathione peroxidase 1 0.955996
G6PC glucose-6-phosphatase, catalytic subunit 0.949101
PDE3B phosphodiesterase 3B, cGMP-inhibited 0.941355
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.939636
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.939636
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.938347
NAMPT nicotinamide phosphoribosyltransferase 0.932337
SREBF1 sterol regulatory element binding transcription factor 1 0.931051
IGF2 insulin-like growth factor 2 0.930193
PYY peptide YY 0.928906
BTBD10 BTB (POZ) domain containing 10 0.922483
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.918633
NES nestin 0.918206
PRF1 perforin 1 (pore forming protein) 0.916069
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 0.914361
ATF4 activating transcription factor 4 0.914361
GPX5 glutathione peroxidase 5 0.903275
CSH2 chorionic somatomammotropin hormone 2 0.900721
THADA thyroid adenoma associated 0.900296
GPX4 glutathione peroxidase 4 0.899445
GLUD1 glutamate dehydrogenase 1 0.893921
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.891374
FFAR4 free fatty acid receptor 4 0.883321
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.874439
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.870217
PKM pyruvate kinase, muscle 0.869373
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.865999
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.865999
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 0.864312
CCK cholecystokinin 0.858837
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.85505
SHB Src homology 2 domain containing adaptor protein B 0.852106
SYT3 synaptotagmin III 0.846644
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.842867
CALCA calcitonin-related polypeptide alpha 0.840769
LIPE lipase, hormone-sensitive 0.838672
SNAP23 synaptosomal-associated protein, 23kDa 0.838252
MLXIPL MLX interacting protein-like 0.836995
ALB albumin 0.828197
JAZF1 JAZF zinc finger 1 0.826104
GAL galanin/GMAP prepropeptide 0.820248
CHGA chromogranin A 0.812309
PARP1 poly (ADP-ribose) polymerase 1 0.810638
FTO fat mass and obesity associated 0.810221
PRL prolactin 0.808134
KCTD20 potassium channel tetramerization domain containing 20 0.808134
STAP2 signal transducing adaptor family member 2 0.807299
STK39 serine threonine kinase 39 0.806047
FURIN furin (paired basic amino acid cleaving enzyme) 0.799375
SUMO4 small ubiquitin-like modifier 4 0.792293
CORO1C coronin, actin binding protein, 1C 0.789796
NOS2 nitric oxide synthase 2, inducible 0.78231
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.780232
NLRP10 NLR family, pyrin domain containing 10 0.77774
PPP4C protein phosphatase 4, catalytic subunit 0.776079
AP3S2 adaptor-related protein complex 3, sigma 2 subunit 0.775664
PFKM phosphofructokinase, muscle 0.773589
JAK2 Janus kinase 2 0.772759
NPY neuropeptide Y 0.766125
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.76364
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 0.76157
UNC13A unc-13 homolog A (C. elegans) 0.754537
MEN1 multiple endocrine neoplasia I 0.749166
BAX BCL2-associated X protein 0.744627
CD38 CD38 molecule 0.74174
CXCL10 chemokine (C-X-C motif) ligand 10 0.73803
FOXP3 forkhead box P3 0.732677
HBA2 hemoglobin, alpha 2 0.73062
CDK4 cyclin-dependent kinase 4 0.724453
INSRR insulin receptor-related receptor 0.720755
CRP C-reactive protein, pentraxin-related 0.720345
DNTT DNA nucleotidylexotransferase 0.719524
SOX17 SRY (sex determining region Y)-box 17 0.717882
FFAR2 free fatty acid receptor 2 0.7146
SIRT1 sirtuin 1 0.711729
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.7105
FRK fyn-related Src family tyrosine kinase 0.70927
PLA2G1B phospholipase A2, group IB (pancreas) 0.706402
STX4 syntaxin 4 0.704764
RBP4 retinol binding protein 4, plasma 0.703536
STAT1 signal transducer and activator of transcription 1, 91kDa 0.702308
HBA1 hemoglobin, alpha 1 0.698625
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.695763
SOCS1 suppressor of cytokine signaling 1 0.694128
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 0.693719
IER3IP1 immediate early response 3 interacting protein 1 0.687592
IL1RN interleukin 1 receptor antagonist 0.685959
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 0.685959
CREB1 cAMP responsive element binding protein 1 0.684327
TGFB1 transforming growth factor, beta 1 0.67984
CELA1 chymotrypsin-like elastase family, member 1 0.679433
RIMS2 regulating synaptic membrane exocytosis 2 0.679025
PCIF1 PDX1 C-terminal inhibiting factor 1 0.67821
BCL2L1 BCL2-like 1 0.676987
TSPAN8 tetraspanin 8 0.676172
ONECUT1 one cut homeobox 1 0.674135
MRPS31 mitochondrial ribosomal protein S31 0.673728
SCGN secretagogin, EF-hand calcium binding protein 0.6721
GRP gastrin-releasing peptide 0.666809
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 0.655024
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.654618
SOX13 SRY (sex determining region Y)-box 13 0.651777
SNAPIN SNAP-associated protein 0.649749
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 0.648938
IGFBP1 insulin-like growth factor binding protein 1 0.632335
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 0.629506
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.628293
NGF nerve growth factor (beta polypeptide) 0.623043
TFCP2 transcription factor CP2 0.622235
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.621428
EXTL3 exostosin-like glycosyltransferase 3 0.614974
CHD4 chromodomain helicase DNA binding protein 4 0.614167
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.612555
CLCN3 chloride channel, voltage-sensitive 3 0.612555
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.610138
AGMO alkylglycerol monooxygenase 0.605306
DLX3 distal-less homeobox 3 0.603697
FABP2 fatty acid binding protein 2, intestinal 0.601283
SYT9 synaptotagmin IX 0.596862
HADH hydroxyacyl-CoA dehydrogenase 0.59646
HYOU1 hypoxia up-regulated 1 0.59646
IL4 interleukin 4 0.593649
NLRP2 NLR family, pyrin domain containing 2 0.591641
ANXA5 annexin A5 0.590437
IL6 interleukin 6 0.577615
STYX serine/threonine/tyrosine interacting protein 0.574416
SOCS3 suppressor of cytokine signaling 3 0.572418
KLF11 Kruppel-like factor 11 0.572018
IFNA1 interferon, alpha 1 0.568424
C2CD4A C2 calcium-dependent domain containing 4A 0.55408
ADIPOR1 adiponectin receptor 1 0.552888
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 0.552093
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.547724
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.546533
ILDR2 immunoglobulin-like domain containing receptor 2 0.546136
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 0.543359
RFX6 regulatory factor X, 6 0.540585
MGAM maltase-glucoamylase 0.539396
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.538604
CAMK2B calcium/calmodulin-dependent protein kinase II beta 0.533065
TRIB3 tribbles pseudokinase 3 0.533065
REG1A regenerating islet-derived 1 alpha 0.531484
REG3A regenerating islet-derived 3 alpha 0.531089
MAPK11 mitogen-activated protein kinase 11 0.530298
CREM cAMP responsive element modulator 0.529113
SYT1 synaptotagmin I 0.527139
IGF1R insulin-like growth factor 1 receptor 0.525166
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.524771
IL2 interleukin 2 0.523588
ACVR1C activin A receptor, type IC 0.5228
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 0.522405
CCND1 cyclin D1 0.519647
CNOT2 CCR4-NOT transcription complex, subunit 2 0.518859
ICAM1 intercellular adhesion molecule 1 0.518465
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.518465
POMC proopiomelanocortin 0.518072
IRF1 interferon regulatory factor 1 0.517284
CCL2 chemokine (C-C motif) ligand 2 0.515317
IL10 interleukin 10 0.512564
HLA-E major histocompatibility complex, class I, E 0.512171
HLA-A major histocompatibility complex, class I, A 0.511384
FAM111A family with sequence similarity 111, member A 0.510599
PTBP1 polypyrimidine tract binding protein 1 0.510206
NPS neuropeptide S 0.507457
STXBP3 syntaxin binding protein 3 0.507457
ADIPOR2 adiponectin receptor 2 0.506672
VAMP3 vesicle-associated membrane protein 3 0.50471
NR0B2 nuclear receptor subfamily 0, group B, member 2 0.503926
GLB1 galactosidase, beta 1 0.501182
GK glycerol kinase 0.498832
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 0.496874
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.495309
RPS6 ribosomal protein S6 0.491791
IFIH1 interferon induced with helicase C domain 1 0.490229
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.488667
TRPM3 transient receptor potential cation channel, subfamily M, member 3 0.487886
LTA lymphotoxin alpha 0.487496
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.485935
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 0.484766
ACE angiotensin I converting enzyme 0.483986
ZDHHC23 zinc finger, DHHC-type containing 23 0.483596
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 0.482428
SIRT4 sirtuin 4 0.481259
SHBG sex hormone-binding globulin 0.48087
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 0.48087
IGFBP3 insulin-like growth factor binding protein 3 0.479702
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 0.478534
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.478534
DMBT1 deleted in malignant brain tumors 1 0.478145
ADRA2A adrenoceptor alpha 2A 0.477756
ACLY ATP citrate lyase 0.474646
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 0.474258
UNC13B unc-13 homolog B (C. elegans) 0.473092
GPR39 G protein-coupled receptor 39 0.470763
C21ORF2 chromosome 21 open reading frame 2 0.470375
DGKB diacylglycerol kinase, beta 90kDa 0.468824
IL1A interleukin 1, alpha 0.468436
HK2 hexokinase 2 0.46766
GIMAP5 GTPase, IMAP family member 5 0.466885
ERI1 exoribonuclease 1 0.466498
TRH thyrotropin-releasing hormone 0.465723
USF1 upstream transcription factor 1 0.465335
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.464174
LDHA lactate dehydrogenase A 0.463787
LGALS4 lectin, galactoside-binding, soluble, 4 0.461852
ACTB actin, beta 0.460305
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 0.4576
NUPR1 nuclear protein, transcriptional regulator, 1 0.456828
CDC42 cell division cycle 42 0.45567
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 0.453355
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.452969
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 0.451428
CELA3B chymotrypsin-like elastase family, member 3B 0.449116
CHCHD2P9 coiled-coil-helix-coiled-coil-helix domain containing 2 pseudogene 9 0.448731
FOXP2 forkhead box P2 0.447192
ZFAND6 zinc finger, AN1-type domain 6 0.442962
TCF3 transcription factor 3 0.442194
ACTG1 actin gamma 1 0.44181
CD276 CD276 molecule 0.441042
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.439507
SSTR5 somatostatin receptor 5 0.439507
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.438739
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.437972
AEBP2 AE binding protein 2 0.437972
VEGFA vascular endothelial growth factor A 0.437205
MLYCD malonyl-CoA decarboxylase 0.436822
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 0.436055
ARNT aryl hydrocarbon receptor nuclear translocator 0.432991
PCNA proliferating cell nuclear antigen 0.43146
LRP11 low density lipoprotein receptor-related protein 11 0.42649
UCN3 urocortin 3 0.42649
EXT2 exostosin glycosyltransferase 2 0.425344
PTEN phosphatase and tensin homolog 0.424199
CSN1S1 casein alpha s1 0.422673
TPO thyroid peroxidase 0.422292
REST RE1-silencing transcription factor 0.420385
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.418861
PTH parathyroid hormone 0.415434
MICA MHC class I polypeptide-related sequence A 0.414673
FASN fatty acid synthase 0.414293
HSPA4 heat shock 70kDa protein 4 0.413532
GSK3B glycogen synthase kinase 3 beta 0.412391
ADRB3 adrenoceptor beta 3 0.407832
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.405176
IRS4 insulin receptor substrate 4 0.405176
COG2 component of oligomeric golgi complex 2 0.40328
PTPN2 protein tyrosine phosphatase, non-receptor type 2 0.402523
NIT2 nitrilase family, member 2 0.402523
PLD1 phospholipase D1, phosphatidylcholine-specific 0.396465
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.396465
FXN frataxin 0.396465
RYR1 ryanodine receptor 1 (skeletal) 0.393064
AIRE autoimmune regulator 0.393064
HMOX1 heme oxygenase 1 0.392686
DPT dermatopontin 0.391176
SOX4 SRY (sex determining region Y)-box 4 0.387027
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 0.385896
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) 0.385143
ATG7 autophagy related 7 0.383637
STAT5B signal transducer and activator of transcription 5B 0.38326
HSH2D hematopoietic SH2 domain containing 0.378372
ATF3 activating transcription factor 3 0.37687
RAB3C RAB3C, member RAS oncogene family 0.373868
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 0.373118
UFM1 ubiquitin-fold modifier 1 0.372743
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.372743
SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14 0.372743
CPB1 carboxypeptidase B1 (tissue) 0.367876
FADD Fas (TNFRSF6)-associated via death domain 0.366754
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 0.364139
CDK5 cyclin-dependent kinase 5 0.364139
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 0.363393
DOC2B double C2-like domains, beta 0.362273
TNS1 tensin 1 0.359292
SPATA21 spermatogenesis associated 21 0.35743
CDX2 caudal type homeobox 2 0.357058
USF2 upstream transcription factor 2, c-fos interacting 0.354826
DDRGK1 DDRGK domain containing 1 0.354826
LMX1A LIM homeobox transcription factor 1, alpha 0.354084
SFXN5 sideroflexin 5 0.352598
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.351856
FOS FBJ murine osteosarcoma viral oncogene homolog 0.350743
PPP5C protein phosphatase 5, catalytic subunit 0.34963
NNAT neuronatin 0.34926
TF transferrin 0.348519
PLRG1 pleiotropic regulator 1 0.348148
NME3 NME/NM23 nucleoside diphosphate kinase 3 0.347778
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.347408
ADM adrenomedullin 0.345928
NOTCH2NL notch 2 N-terminal like 0.344818
PTTG1 pituitary tumor-transforming 1 0.344818
SOX9 SRY (sex determining region Y)-box 9 0.34371
FBP1 fructose-1,6-bisphosphatase 1 0.342971
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.342233
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) 0.341863
HRK harakiri, BCL2 interacting protein 0.341863
NOTCH2 notch 2 0.341863
IL2RA interleukin 2 receptor, alpha 0.341495
SLC30A4 solute carrier family 30 (zinc transporter), member 4 0.340757
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 0.338914
SSTR2 somatostatin receptor 2 0.335968
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.335233
OMA1 OMA1 zinc metallopeptidase 0.335233
MMD monocyte to macrophage differentiation-associated 0.334865
CISH cytokine inducible SH2-containing protein 0.333763
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 0.333396
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.331194
CTH cystathionine gamma-lyase 0.330094
FEM1B fem-1 homolog b (C. elegans) 0.330094
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.329361
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.328994
STC1 stanniocalcin 1 0.327896
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.327164
NELFCD negative elongation factor complex member C/D 0.326798
INSM1 insulinoma-associated 1 0.324239
TM7SF3 transmembrane 7 superfamily member 3 0.323874
CRTC2 CREB regulated transcription coactivator 2 0.322779
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.320591
CPA6 carboxypeptidase A6 0.319863
ALX3 ALX homeobox 3 0.319498
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 0.319134
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.318407
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.318407
PFKL phosphofructokinase, liver 0.317315
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.316588
CREB3L1 cAMP responsive element binding protein 3-like 1 0.315861
DLK1 delta-like 1 homolog (Drosophila) 0.315861
SCG5 secretogranin V 0.313683
NRK Nik related kinase 0.31332
HTT huntingtin 0.31332
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.31332
ADCY8 adenylate cyclase 8 (brain) 0.31187
GUCY2C guanylate cyclase 2C 0.311507
SLC30A5 solute carrier family 30 (zinc transporter), member 5 0.311507
TLR2 toll-like receptor 2 0.311145
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.309335
NPR1 natriuretic peptide receptor 1 0.309335
IDE insulin-degrading enzyme 0.307889
TXN thioredoxin 0.307528
STK11 serine/threonine kinase 11 0.307528
APOC3 apolipoprotein C-III 0.307167
CASR calcium-sensing receptor 0.307167
PDZD2 PDZ domain containing 2 0.306805
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.303559
IL2RG interleukin 2 receptor, gamma 0.303198
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 0.301758
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 0.301398
REEP2 receptor accessory protein 2 0.299601
TRPM5 transient receptor potential cation channel, subfamily M, member 5 0.298524
NTS neurotensin 0.298165
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.29673
KIRREL2 kin of IRRE like 2 (Drosophila) 0.296372
GPER1 G protein-coupled estrogen receptor 1 0.296013
EIF2A eukaryotic translation initiation factor 2A, 65kDa 0.296013
DUSP9 dual specificity phosphatase 9 0.295655
KRT20 keratin 20, type I 0.295297
RNLS renalase, FAD-dependent amine oxidase 0.294581
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.294223
CALB1 calbindin 1, 28kDa 0.293866
THY1 Thy-1 cell surface antigen 0.293866
PTPMT1 protein tyrosine phosphatase, mitochondrial 1 0.293508
MTMR9 myotubularin related protein 9 0.292793
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 0.292079
SGPP1 sphingosine-1-phosphate phosphatase 1 0.291722
TMEM184A transmembrane protein 184A 0.290652
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.289939
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit 0.289582
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.28887
FTH1 ferritin, heavy polypeptide 1 0.287803
ARX aristaless related homeobox 0.287803
VIP vasoactive intestinal peptide 0.286736
TLE2 transducin-like enhancer of split 2 0.286381
SFXN2 sideroflexin 2 0.285671
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) 0.285316
SSTR1 somatostatin receptor 1 0.283899
KCNK16 potassium channel, two pore domain subfamily K, member 16 0.283899
TFAM transcription factor A, mitochondrial 0.283545
TLR3 toll-like receptor 3 0.283545
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.283191
RBM47 RNA binding motif protein 47 0.282837
SPAG9 sperm associated antigen 9 0.281423
FADS1 fatty acid desaturase 1 0.279659
H3F3B H3 histone, family 3B (H3.3B) 0.279307
H3F3A H3 histone, family 3A 0.279307
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.278603
GPR75 G protein-coupled receptor 75 0.276495
ONECUT2 one cut homeobox 2 0.275794
CXCL12 chemokine (C-X-C motif) ligand 12 0.275094
FTL ferritin, light polypeptide 0.273346
CHGB chromogranin B 0.2723
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.271952
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 0.270909
MYO5A myosin VA (heavy chain 12, myoxin) 0.270561
EGR1 early growth response 1 0.268137
CLECL1 C-type lectin-like 1 0.268137
ZBED3 zinc finger, BED-type containing 3 0.268137
ETNPPL ethanolamine-phosphate phospho-lyase 0.265381
CD5 CD5 molecule 0.264696
SFXN3 sideroflexin 3 0.264353
CAMK2D calcium/calmodulin-dependent protein kinase II delta 0.264296
RPS15 ribosomal protein S15 0.263669
GPR84 G protein-coupled receptor 84 0.263669
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 0.262304
PPP6C protein phosphatase 6, catalytic subunit 0.262304
MAPK3 mitogen-activated protein kinase 3 0.261624
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.260606
PRKD1 protein kinase D1 0.260606
SYP synaptophysin 0.257572
VGF VGF nerve growth factor inducible 0.2559
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 0.255234
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 0.254239
ADAM30 ADAM metallopeptidase domain 30 0.253248
SCG2 secretogranin II 0.25259
EMC10 ER membrane protein complex subunit 10 0.252261
CSN3 casein kappa 0.252261
ESR2 estrogen receptor 2 (ER beta) 0.251934
SLC39A14 solute carrier family 39 (zinc transporter), member 14 0.251279
CPN1 carboxypeptidase N, polypeptide 1 0.251279
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.251279
DLL1 delta-like 1 (Drosophila) 0.250627
PYGB phosphorylase, glycogen; brain 0.250301
GPR83 G protein-coupled receptor 83 0.250301
ACACB acetyl-CoA carboxylase beta 0.249977
FFAR3 free fatty acid receptor 3 0.249653
IGLV3-21 immunoglobulin lambda variable 3-21 0.24676
DYNLT3 dynein, light chain, Tctex-type 3 0.246442
CA2 carbonic anhydrase II 0.246124
CXCR3 chemokine (C-X-C motif) receptor 3 0.246124
DISP2 dispatched homolog 2 (Drosophila) 0.245491
HSPA14 heat shock 70kDa protein 14 0.245175
DIABLO diablo, IAP-binding mitochondrial protein 0.245175
SELL selectin L 0.24486
TLR4 toll-like receptor 4 0.244545
MIR27B microRNA 27b 0.244232
BGLAP bone gamma-carboxyglutamate (gla) protein 0.243605
NOS1 nitric oxide synthase 1 (neuronal) 0.242672
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 0.242054
ZC3H11A zinc finger CCCH-type containing 11A 0.241746
SOX2 SRY (sex determining region Y)-box 2 0.240826
MAPK9 mitogen-activated protein kinase 9 0.240216
ARFIP1 ADP-ribosylation factor interacting protein 1 0.238706
SUN3 Sad1 and UNC84 domain containing 3 0.238706
SYCN syncollin 0.238108
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.237216
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 0.236921
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.236332
AK6 adenylate kinase 6 0.234878
FEM1C fem-1 homolog c (C. elegans) 0.234878
NKX6-2 NK6 homeobox 2 0.23459
ATP10D ATPase, class V, type 10D 0.233446
HMG20A high mobility group 20A 0.233162
TG thyroglobulin 0.23176
HIST1H4I histone cluster 1, H4i 0.230931
HIST1H4H histone cluster 1, H4h 0.230931
HIST1H4J histone cluster 1, H4j 0.230931
HIST1H4K histone cluster 1, H4k 0.230931
HIST1H4D histone cluster 1, H4d 0.230931
HIST1H4C histone cluster 1, H4c 0.230931
HIST1H4E histone cluster 1, H4e 0.230931
HIST1H4F histone cluster 1, H4f 0.230931
HIST1H4A histone cluster 1, H4a 0.230931
HIST2H4B histone cluster 2, H4b 0.230931
HIST1H4B histone cluster 1, H4b 0.230931
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.230656
STX6 syntaxin 6 0.230656
HIST2H4A histone cluster 2, H4a 0.230656
NOVA1 neuro-oncological ventral antigen 1 0.230382
GAN gigaxonin 0.23011
HIPK3 homeodomain interacting protein kinase 3 0.229839
HIST4H4 histone cluster 4, H4 0.229839
HIST1H4L histone cluster 1, H4l 0.229839
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 0.229299
FKBP1A FK506 binding protein 1A, 12kDa 0.229299
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 0.229299
ARNTL aryl hydrocarbon receptor nuclear translocator-like 0.228234
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.22797
FOXA3 forkhead box A3 0.227707
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 0.227186
SYT4 synaptotagmin IV 0.226411
B2M beta-2-microglobulin 0.226155
ASS1 argininosuccinate synthase 1 0.226155
PPARD peroxisome proliferator-activated receptor delta 0.226155
NOTCH1 notch 1 0.2259
TGOLN2 trans-golgi network protein 2 0.224645
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.222938
FGD1 FYVE, RhoGEF and PH domain containing 1 0.22246
ATF2 activating transcription factor 2 0.221989
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.221521
GSR glutathione reductase 0.221061
PYGL phosphorylase, glycogen, liver 0.220604
SYT8 synaptotagmin VIII 0.220378
APOB apolipoprotein B 0.219485
SP1 Sp1 transcription factor 0.219264
GPR27 G protein-coupled receptor 27 0.21883
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.218613
MARK2 MAP/microtubule affinity-regulating kinase 2 0.218613
PRSS21 protease, serine, 21 (testisin) 0.218186
SSR4 signal sequence receptor, delta 0.218186
PNPLA2 patatin-like phospholipase domain containing 2 0.218186
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.217974
SPATA2 spermatogenesis associated 2 0.217974
PYGM phosphorylase, glycogen, muscle 0.217762
CD40LG CD40 ligand 0.216933
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.216126
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 0.215341
DMXL2 Dmx-like 2 0.215341
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.214954
RAB2A RAB2A, member RAS oncogene family 0.214765
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.214765
CD48 CD48 molecule 0.214576
SNX19 sorting nexin 19 0.214388
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 0.214202
SPHK1 sphingosine kinase 1 0.212965
PTHLH parathyroid hormone-like hormone 0.212761
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.206775
SPHK2 sphingosine kinase 2 0.204208
NTSR2 neurotensin receptor 2 0.202818
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 0.196296
SCG3 secretogranin III 0.195726
RIMS1 regulating synaptic membrane exocytosis 1 0.19526
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 0.194996
STX3 syntaxin 3 0.194748
NPY2R neuropeptide Y receptor Y2 0.193548
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.193179
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.192813
PROK1 prokineticin 1 0.192465
CDK11A cyclin-dependent kinase 11A 0.191526
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.190865
MFN1 mitofusin 1 0.190005
RAD52 RAD52 homolog (S. cerevisiae) 0.189559
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.189453
RUNDC3A RUN domain containing 3A 0.189209
BAD BCL2-associated agonist of cell death 0.188968
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.188774
DNM1L dynamin 1-like 0.188281
APOA5 apolipoprotein A-V 0.188202
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic) 0.187791
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 0.187516
WDR13 WD repeat domain 13 0.187474
NLRP3 NLR family, pyrin domain containing 3 0.187346
DUX4L9 double homeobox 4 like 9 0.185821
DUX4L4 double homeobox 4 like 4 0.185821
NALCN sodium leak channel, non selective 0.183862
MAP3K9 mitogen-activated protein kinase kinase kinase 9 0.183394
HDAC3 histone deacetylase 3 0.18272
GJC1 gap junction protein, gamma 1, 45kDa 0.181779
REM2 RAS (RAD and GEM)-like GTP binding 2 0.181588
GRM5 glutamate receptor, metabotropic 5 0.180587
STX2 syntaxin 2 0.179823
KLF7 Kruppel-like factor 7 (ubiquitous) 0.178401
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain 0.177867
ANXA11 annexin A11 0.177612
RAP2A RAP2A, member of RAS oncogene family 0.177259
CTSB cathepsin B 0.175047
DUX4L8 double homeobox 4 like 8 0.174058
MOCS2 molybdenum cofactor synthesis 2 0.173659
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 0.173178
HCRTR1 hypocretin (orexin) receptor 1 0.172931
PLD2 phospholipase D2 0.172931
ARF6 ADP-ribosylation factor 6 0.172832
HDAC1 histone deacetylase 1 0.17253
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 0.172479
MIR107 microRNA 107 0.172402
TCF12 transcription factor 12 0.171988
STK3 serine/threonine kinase 3 0.170405
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 0.169291
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 0.16926
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.169107
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 0.168923
BLK BLK proto-oncogene, Src family tyrosine kinase 0.167059
SIRT3 sirtuin 3 0.16689
STK26 serine/threonine protein kinase 26 0.165852
NRGN neurogranin (protein kinase C substrate, RC3) 0.165673
GRB2 growth factor receptor-bound protein 2 0.165493
RAP2B RAP2B, member of RAS oncogene family 0.165058
RAB1B RAB1B, member RAS oncogene family 0.164984
SAR1A secretion associated, Ras related GTPase 1A 0.164724
ARF3 ADP-ribosylation factor 3 0.164576
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 0.164464
SYT2 synaptotagmin II 0.16416
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.164084
SLC16A4 solute carrier family 16, member 4 0.16393
GSK3A glycogen synthase kinase 3 alpha 0.163892
PTS 6-pyruvoyltetrahydropterin synthase 0.163031
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.162912
PITX1 paired-like homeodomain 1 0.161726
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 0.161557
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.160442
AATF apoptosis antagonizing transcription factor 0.159147
MAP2K3 mitogen-activated protein kinase kinase 3 0.158311
ACVR1B activin A receptor, type IB 0.15817
AMPD2 adenosine monophosphate deaminase 2 0.157691
TRPM4 transient receptor potential cation channel, subfamily M, member 4 0.156718
HDAC9 histone deacetylase 9 0.155818
AHR aryl hydrocarbon receptor 0.154054
ADRA2C adrenoceptor alpha 2C 0.153891
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.153621
CNTN5 contactin 5 0.152638
ATG5 autophagy related 5 0.152137
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.151858
MDK midkine (neurite growth-promoting factor 2) 0.150008
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.14875
ARAF A-Raf proto-oncogene, serine/threonine kinase 0.148385
CARD17 caspase recruitment domain family, member 17 0.146511
SCARB1 scavenger receptor class B, member 1 0.145611
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.144427
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.144031
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 0.143827