pancreatic beta cell line Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
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Genes

221 proteins co-occuring with the tissue pancreatic beta cell line in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
FOXM1 forkhead box M1 2.59766
INS insulin 1.92893
NIT1 nitrilase 1 1.76575
IAPP islet amyloid polypeptide 1.27471
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 1.21045
GCK glucokinase (hexokinase 4) 1.17314
CAMK2D calcium/calmodulin-dependent protein kinase II delta 1.08192
CORO1C coronin, actin binding protein, 1C 1.07794
IRS2 insulin receptor substrate 2 1.06471
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 1.0603
IRS4 insulin receptor substrate 4 1.03829
HMX1 H6 family homeobox 1 1.03741
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.02425
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 1.02118
GIP gastric inhibitory polypeptide 1.01069
HNF1A HNF1 homeobox A 0.979783
FFAR1 free fatty acid receptor 1 0.979783
RUNDC3A RUN domain containing 3A 0.951685
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 0.950823
GPR27 G protein-coupled receptor 27 0.947378
PTPMT1 protein tyrosine phosphatase, mitochondrial 1 0.926336
GCG glucagon 0.926336
SYTL4 synaptotagmin-like 4 0.906682
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic) 0.873172
PCSK2 proprotein convertase subtilisin/kexin type 2 0.858837
WDR13 WD repeat domain 13 0.857153
RAB27A RAB27A, member RAS oncogene family 0.856732
BTBD10 BTB (POZ) domain containing 10 0.813144
DUX4L9 double homeobox 4 like 9 0.781063
DUX4L4 double homeobox 4 like 4 0.781063
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.767783
FOXO1 forkhead box O1 0.758259
GPR119 G protein-coupled receptor 119 0.747102
CPE carboxypeptidase E 0.739266
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 0.735971
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 0.726507
FEM1B fem-1 homolog b (C. elegans) 0.724863
TRIB3 tribbles pseudokinase 3 0.719113
NALCN sodium leak channel, non selective 0.704764
IL1B interleukin 1, beta 0.699444
MAP3K9 mitogen-activated protein kinase kinase kinase 9 0.688409
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 0.688
RIMS2 regulating synaptic membrane exocytosis 2 0.680656
REM2 RAS (RAD and GEM)-like GTP binding 2 0.631123
TFCP2 transcription factor CP2 0.624254
INSR insulin receptor 0.623446
IGF1 insulin-like growth factor 1 (somatomedin C) 0.586828
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.582019
ANXA5 annexin A5 0.572818
KLF7 Kruppel-like factor 7 (ubiquitous) 0.548517
HNF1B HNF1 homeobox B 0.548517
PDX1 pancreatic and duodenal homeobox 1 0.545739
HNF4A hepatocyte nuclear factor 4, alpha 0.537812
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain 0.536625
NTSR2 neurotensin receptor 2 0.536229
ANXA11 annexin A11 0.531089
TMEM27 transmembrane protein 27 0.528323
FAM3B family with sequence similarity 3, member B 0.527534
SYT3 synaptotagmin III 0.525166
RAP2A RAP2A, member of RAS oncogene family 0.523588
PCSK1 proprotein convertase subtilisin/kexin type 1 0.521223
PAX4 paired box 4 0.506672
MAPK8 mitogen-activated protein kinase 8 0.505495
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 0.504318
JUN jun proto-oncogene 0.503141
MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A 0.479312
CREB3L1 cAMP responsive element binding protein 3-like 1 0.472704
SCG3 secretogranin III 0.472315
SREBF1 sterol regulatory element binding transcription factor 1 0.466885
DUX4L8 double homeobox 4 like 8 0.463787
JAK2 Janus kinase 2 0.461078
MOCS2 molybdenum cofactor synthesis 2 0.457214
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 0.449501
KLF11 Kruppel-like factor 11 0.449116
BAX BCL2-associated X protein 0.447961
RIMS1 regulating synaptic membrane exocytosis 1 0.447961
PLD2 phospholipase D2 0.445653
ARF6 ADP-ribosylation factor 6 0.444115
GAL galanin/GMAP prepropeptide 0.443347
MIR107 microRNA 107 0.437589
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 0.434906
HK1 hexokinase 1 0.430312
ACVR1C activin A receptor, type IC 0.422292
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.420385
RAB3A RAB3A, member RAS oncogene family 0.417337
STK3 serine/threonine kinase 3 0.409351
CREB1 cAMP responsive element binding protein 1 0.40366
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 0.394576
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.392686
BTC betacellulin 0.384766
PAX6 paired box 6 0.38326
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.373493
PTPRN protein tyrosine phosphatase, receptor type, N 0.373493
BLK BLK proto-oncogene, Src family tyrosine kinase 0.368624
ATF6 activating transcription factor 6 0.367876
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 0.36302
RPH3A rabphilin 3A 0.358546
GCKR glucokinase (hexokinase 4) regulator 0.35557
STK26 serine/threonine protein kinase 26 0.35557
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.352227
RAP2B RAP2B, member of RAS oncogene family 0.347408
RAB1B RAB1B, member RAS oncogene family 0.346668
SAR1A secretion associated, Ras related GTPase 1A 0.344079
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.34334
ARF3 ADP-ribosylation factor 3 0.342602
SYT2 synaptotagmin II 0.338545
GSK3A glycogen synthase kinase 3 alpha 0.335968
NNAT neuronatin 0.334865
TRPM5 transient receptor potential cation channel, subfamily M, member 5 0.332661
GLP1R glucagon-like peptide 1 receptor 0.328262
CAPN10 calpain 10 0.328262
PTS 6-pyruvoyltetrahydropterin synthase 0.327896
SLC30A8 solute carrier family 30 (zinc transporter), member 8 0.326798
FOXA2 forkhead box A2 0.322779
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.305361
CDK11A cyclin-dependent kinase 11A 0.30032
HRK harakiri, BCL2 interacting protein 0.29673
CCND1 cyclin D1 0.29673
AATF apoptosis antagonizing transcription factor 0.294939
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.292793
FFAR4 free fatty acid receptor 4 0.292079
ACACB acetyl-CoA carboxylase beta 0.289582
ACVR1B activin A receptor, type IB 0.287447
AMPD2 adenosine monophosphate deaminase 2 0.283899
TNF tumor necrosis factor 0.279659
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.278251
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 0.277549
TRPM4 transient receptor potential cation channel, subfamily M, member 4 0.276846
PC pyruvate carboxylase 0.271256
SCG5 secretogranin V 0.270909
MLYCD malonyl-CoA decarboxylase 0.269867
SPHK1 sphingosine kinase 1 0.269798
SIRT4 sirtuin 4 0.268482
MAPK9 mitogen-activated protein kinase 9 0.264011
ADRA2C adrenoceptor alpha 2C 0.257907
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.257572
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.251934
RAD52 RAD52 homolog (S. cerevisiae) 0.247079
EGR1 early growth response 1 0.24486
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.244545
PARP1 poly (ADP-ribose) polymerase 1 0.241746
STX3 syntaxin 3 0.238706
ISL1 ISL LIM homeobox 1 0.235167
BAD BCL2-associated agonist of cell death 0.23459
RPS6 ribosomal protein S6 0.230656
ARAF A-Raf proto-oncogene, serine/threonine kinase 0.228497
REG3A regenerating islet-derived 3 alpha 0.226926
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 0.226667
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.224645
DNM1L dynamin 1-like 0.222699
SPHK2 sphingosine kinase 2 0.221521
APOA5 apolipoprotein A-V 0.221521
VAMP3 vesicle-associated membrane protein 3 0.221291
CARD17 caspase recruitment domain family, member 17 0.221061
FOXP2 forkhead box P2 0.219047
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.214388
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.213291
ACLY ATP citrate lyase 0.198332
NPY2R neuropeptide Y receptor Y2 0.196424
PROK1 prokineticin 1 0.195514
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 0.195216
GJD2 gap junction protein, delta 2, 36kDa 0.194544
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.19417
MFN1 mitofusin 1 0.193441
ATG7 autophagy related 7 0.192465
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.192395
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 0.191327
NLRP3 NLR family, pyrin domain containing 3 0.191184
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.189967
TXNIP thioredoxin interacting protein 0.189264
CTH cystathionine gamma-lyase 0.188166
HDAC3 histone deacetylase 3 0.187344
GJC1 gap junction protein, gamma 1, 45kDa 0.186581
CNOT2 CCR4-NOT transcription complex, subunit 2 0.185892
GRM5 glutamate receptor, metabotropic 5 0.185621
CREM cAMP responsive element modulator 0.185561
STX2 syntaxin 2 0.185009
CCND2 cyclin D2 0.181719
CTSB cathepsin B 0.181253
HCRTR1 hypocretin (orexin) receptor 1 0.179614
HDAC1 histone deacetylase 1 0.179304
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 0.179264
TCF12 transcription factor 12 0.178886
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.178456
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.178288
PNPLA2 patatin-like phospholipase domain containing 2 0.177263
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 0.176802
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 0.17652
SIRT3 sirtuin 3 0.174942
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.174406
NRGN neurogranin (protein kinase C substrate, RC3) 0.173993
GRB2 growth factor receptor-bound protein 2 0.173853
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 0.173044
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.172748
SLC16A4 solute carrier family 16, member 4 0.172626
USF2 upstream transcription factor 2, c-fos interacting 0.172504
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.172198
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.171821
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.171726
PITX1 paired-like homeodomain 1 0.170877
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 0.170743
PKLR pyruvate kinase, liver and RBC 0.168653
PYGB phosphorylase, glycogen; brain 0.168425
PYGL phosphorylase, glycogen, liver 0.168311
MAP2K3 mitogen-activated protein kinase kinase 3 0.168122
PYGM phosphorylase, glycogen, muscle 0.167812
CAMK2B calcium/calmodulin-dependent protein kinase II beta 0.166571
HDAC9 histone deacetylase 9 0.16607
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.164858
AHR aryl hydrocarbon receptor 0.164591
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.164229
CNTN5 contactin 5 0.163395
PKM pyruvate kinase, muscle 0.1633
MAPK3 mitogen-activated protein kinase 3 0.163253
ATG5 autophagy related 5 0.162968
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.162729
MDK midkine (neurite growth-promoting factor 2) 0.161135
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.160038
IRS1 insulin receptor substrate 1 0.159714
SCARB1 scavenger receptor class B, member 1 0.157251
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 0.155634