paget's disease of bone Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description A bone formation disease that has_material_basis_in hyperactive osteoclast which results_in abnormal osteoblast bone formation located_in skull, located_in pelvis, located_in vertebral column, located_in set of limbs. (Human Disease Ontology, DOID_5408)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:5408
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Genes

33 genes associated with the disease paget's disease of bone in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
OPTN optineurin 2.39232
DCSTAMP dendrocyte expressed seven transmembrane protein 1.88858
PML promyelocytic leukemia 1.77455
RIN3 Ras and Rab interactor 3 1.60875
NUP205 nucleoporin 205kDa 1.51636
PIGN phosphatidylinositol glycan anchor biosynthesis, class N 1.38561
SLC25A43 solute carrier family 25, member 43 1.31635
UBXN4 UBX domain protein 4 1.15428
LOC339862 uncharacterized LOC339862 1.12589
PRL prolactin 1.07599
SHISA9 shisa family member 9 1.05686
ZRANB3 zinc finger, RAN-binding domain containing 3 1.04977
R3HDM1 R3H domain containing 1 1.04795
LCT lactase 1.04072
HPSE2 heparanase 2 (inactive) 1.03557
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 0.99638
DGKQ diacylglycerol kinase, theta 110kDa 0.941109
ABI3BP ABI family, member 3 (NESH) binding protein 0.91969
PARK2 parkin RBR E3 ubiquitin protein ligase 0.896302
TLR1 toll-like receptor 1 0.892579
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.882764
MSH2 mutS homolog 2 0.882152
DARS aspartyl-tRNA synthetase 0.88094
RANBP17 RAN binding protein 17 0.871773
CCDC83 coiled-coil domain containing 83 0.865959
MTUS2 microtubule associated tumor suppressor candidate 2 0.861951
SDK2 sidekick cell adhesion molecule 2 0.840288
NFRKB nuclear factor related to kappaB binding protein 0.814185
CSNK2A2 casein kinase 2, alpha prime polypeptide 0.810892
ANK2 ankyrin 2, neuronal 0.809818
MAP3K19 mitogen-activated protein kinase kinase kinase 19 0.797385
PTPRD protein tyrosine phosphatase, receptor type, D 0.752656
NCOA7 nuclear receptor coactivator 7 0.724198
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