oxyphenbutazone-6844 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the oxyphenbutazone-6844 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABHD4 abhydrolase domain containing 4
ADGRA2 adhesion G protein-coupled receptor A2
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
APOE apolipoprotein E
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BTN3A1 butyrophilin, subfamily 3, member A1
CCDC134 coiled-coil domain containing 134
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CLGN calmegin
CSRP2 cysteine and glycine-rich protein 2
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DFNB31 deafness, autosomal recessive 31
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DOCK6 dedicator of cytokinesis 6
DRD1 dopamine receptor D1
DTNA dystrobrevin, alpha
EGFR epidermal growth factor receptor
EHBP1L1 EH domain binding protein 1-like 1
EPHX2 epoxide hydrolase 2, cytoplasmic
FLT3LG fms-related tyrosine kinase 3 ligand
FN1 fibronectin 1
FOSL1 FOS-like antigen 1
FRMD1 FERM domain containing 1
GABARAPL1 GABA(A) receptor-associated protein like 1
GCLM glutamate-cysteine ligase, modifier subunit
GPR176 G protein-coupled receptor 176
GPX3 glutathione peroxidase 3
GRM1 glutamate receptor, metabotropic 1
GRM2 glutamate receptor, metabotropic 2
GZMK granzyme K (granzyme 3; tryptase II)
HMHA1 histocompatibility (minor) HA-1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IL1B interleukin 1, beta
IL6R interleukin 6 receptor
KAT6A K(lysine) acetyltransferase 6A
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KRT16 keratin 16, type I
KRT6B keratin 6B, type II
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP1B microtubule-associated protein 1B
MAPK14 mitogen-activated protein kinase 14
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MLXIPL MLX interacting protein-like
MVB12B multivesicular body subunit 12B
MX1 MX dynamin-like GTPase 1
NAAA N-acylethanolamine acid amidase
NDRG1 N-myc downstream regulated 1
NUPR1 nuclear protein, transcriptional regulator, 1
OSGIN1 oxidative stress induced growth inhibitor 1
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PDAP1 PDGFA associated protein 1
PDE4DIP phosphodiesterase 4D interacting protein
PEX16 peroxisomal biogenesis factor 16
PLEKHA6 pleckstrin homology domain containing, family A member 6
POFUT1 protein O-fucosyltransferase 1
PRPH2 peripherin 2 (retinal degeneration, slow)
PVRL3 poliovirus receptor-related 3
RBFA ribosome binding factor A (putative)
RFPL3 ret finger protein-like 3
RIF1 replication timing regulatory factor 1
RND1 Rho family GTPase 1
RUNX1 runt-related transcription factor 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SH3BGR SH3 domain binding glutamate-rich protein
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIK3 SIK family kinase 3
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX9 SRY (sex determining region Y)-box 9
SQSTM1 sequestosome 1
TCP11L1 t-complex 11, testis-specific-like 1
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TM4SF5 transmembrane 4 L six family member 5
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TPPP tubulin polymerization promoting protein
TRD T cell receptor delta locus
TRIM36 tripartite motif containing 36
TTLL7 tubulin tyrosine ligase-like family member 7
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UNKL unkempt family zinc finger-like
USP27X ubiquitin specific peptidase 27, X-linked
XDH xanthine dehydrogenase
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF532 zinc finger protein 532
ZNF862 zinc finger protein 862
ZSCAN18 zinc finger and SCAN domain containing 18
ZSCAN2 zinc finger and SCAN domain containing 2

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
AKAP12 A kinase (PRKA) anchor protein 12
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALS2CL ALS2 C-terminal like
ANKRD28 ankyrin repeat domain 28
ANP32A-IT1 ANP32A intronic transcript 1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BMP5 bone morphogenetic protein 5
BTF3P11 basic transcription factor 3 pseudogene 11
C19ORF73 chromosome 19 open reading frame 73
C4ORF29 chromosome 4 open reading frame 29
CA5BP1 carbonic anhydrase VB pseudogene 1
CCNE2 cyclin E2
CENPT centromere protein T
CLCN6 chloride channel, voltage-sensitive 6
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DEAF1 DEAF1 transcription factor
DHRS11 dehydrogenase/reductase (SDR family) member 11
DMTN dematin actin binding protein
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM169A family with sequence similarity 169, member A
FAM204A family with sequence similarity 204, member A
FAM63A family with sequence similarity 63, member A
GHR growth hormone receptor
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR19 G protein-coupled receptor 19
GSTTP1 glutathione S-transferase theta pseudogene 1
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HDAC7 histone deacetylase 7
HIST1H2AJ histone cluster 1, H2aj
HIST1H4F histone cluster 1, H4f
HK2 hexokinase 2
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HOXC8 homeobox C8
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGSF1 immunoglobulin superfamily, member 1
INO80D INO80 complex subunit D
ITPKB inositol-trisphosphate 3-kinase B
KIAA0125 KIAA0125
LINC00115 long intergenic non-protein coding RNA 115
LOC729164 hCG1732469
LY6D lymphocyte antigen 6 complex, locus D
MEIS2 Meis homeobox 2
MYL5 myosin, light chain 5, regulatory
NABP2 nucleic acid binding protein 2
NFS1 NFS1 cysteine desulfurase
NRSN2 neurensin 2
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PAQR6 progestin and adipoQ receptor family member VI
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PELI1 pellino E3 ubiquitin protein ligase 1
PEX26 peroxisomal biogenesis factor 26
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
POM121 POM121 transmembrane nucleoporin
PP14571 uncharacterized LOC100130449
PRICKLE3 prickle homolog 3 (Drosophila)
PSG4 pregnancy specific beta-1-glycoprotein 4
RAB3A RAB3A, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
SAMHD1 SAM domain and HD domain 1
SAYSD1 SAYSVFN motif domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SCRN3 secernin 3
SEC14L2 SEC14-like 2 (S. cerevisiae)
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SOBP sine oculis binding protein homolog (Drosophila)
SSBP3 single stranded DNA binding protein 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
THBS3 thrombospondin 3
TLR5 toll-like receptor 5
TM6SF1 transmembrane 6 superfamily member 1
TMEM120B transmembrane protein 120B
TMEM121 transmembrane protein 121
TMEM254 transmembrane protein 254
TRIM21 tripartite motif containing 21
TTBK2 tau tubulin kinase 2
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
TWISTNB TWIST neighbor
USB1 U6 snRNA biogenesis 1
USP18 ubiquitin specific peptidase 18
WDR76 WD repeat domain 76
WLS wntless Wnt ligand secretion mediator
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF696 zinc finger protein 696
ZNF701 zinc finger protein 701
ZW10 zw10 kinetochore protein