oxyphenbutazone-4506 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the oxyphenbutazone-4506 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AKAP8L A kinase (PRKA) anchor protein 8-like
APAF1 apoptotic peptidase activating factor 1
ARHGAP22 Rho GTPase activating protein 22
ARNT aryl hydrocarbon receptor nuclear translocator
ARSD arylsulfatase D
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAT1 alpha tubulin acetyltransferase 1
ATP9A ATPase, class II, type 9A
BMPR1B bone morphogenetic protein receptor, type IB
CD68 CD68 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CLEC3B C-type lectin domain family 3, member B
CNR2 cannabinoid receptor 2 (macrophage)
CREB3L1 cAMP responsive element binding protein 3-like 1
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CYTH1 cytohesin 1
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DENND6B DENN/MADD domain containing 6B
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DMXL2 Dmx-like 2
DUSP9 dual specificity phosphatase 9
ELN elastin
ELOVL2 ELOVL fatty acid elongase 2
EPN1 epsin 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FAS Fas cell surface death receptor
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGFR4 fibroblast growth factor receptor 4
FUBP1 far upstream element (FUSE) binding protein 1
GABARAPL1 GABA(A) receptor-associated protein like 1
GABARAPL3 GABA(A) receptors associated protein like 3, pseudogene
GLP1R glucagon-like peptide 1 receptor
GPATCH4 G patch domain containing 4
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GSN gelsolin
GSTTP1 glutathione S-transferase theta pseudogene 1
HAB1 B1 for mucin
HEMK1 HemK methyltransferase family member 1
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IKZF1 IKAROS family zinc finger 1 (Ikaros)
INSR insulin receptor
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KANSL3 KAT8 regulatory NSL complex subunit 3
KCTD17 potassium channel tetramerization domain containing 17
KIAA1467 KIAA1467
KLF12 Kruppel-like factor 12
KLF6 Kruppel-like factor 6
KMT2A lysine (K)-specific methyltransferase 2A
LHX2 LIM homeobox 2
LIG3 ligase III, DNA, ATP-dependent
MAL mal, T-cell differentiation protein
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MEGF9 multiple EGF-like-domains 9
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MON2 MON2 homolog (S. cerevisiae)
MYH14 myosin, heavy chain 14, non-muscle
MYL10 myosin, light chain 10, regulatory
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NOTCH4 notch 4
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OLFML2B olfactomedin-like 2B
OTOR otoraplin
PADI2 peptidyl arginine deiminase, type II
PDE10A phosphodiesterase 10A
PDE4B phosphodiesterase 4B, cAMP-specific
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKNOX2 PBX/knotted 1 homeobox 2
PPARD peroxisome proliferator-activated receptor delta
PVR poliovirus receptor
RAB31 RAB31, member RAS oncogene family
RARA retinoic acid receptor, alpha
RBM34 RNA binding motif protein 34
RUNX1 runt-related transcription factor 1
RUNX2 runt-related transcription factor 2
SMAD1 SMAD family member 1
STOML1 stomatin (EPB72)-like 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TACR1 tachykinin receptor 1
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TMEM74B transmembrane protein 74B
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TPM3 tropomyosin 3
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TTC12 tetratricopeptide repeat domain 12
VAV2 vav 2 guanine nucleotide exchange factor
VCX2 variable charge, X-linked 2
YPEL1 yippee-like 1 (Drosophila)
ZC2HC1C zinc finger, C2HC-type containing 1C
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF154 zinc finger protein 154
ZNF747 zinc finger protein 747
ZSCAN2 zinc finger and SCAN domain containing 2

decreased expression

Symbol Name
ADGRB2 adhesion G protein-coupled receptor B2
AGMAT agmatine ureohydrolase (agmatinase)
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARMCX4 armadillo repeat containing, X-linked 4
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
BTBD18 BTB (POZ) domain containing 18
C14ORF93 chromosome 14 open reading frame 93
C17ORF53 chromosome 17 open reading frame 53
C1ORF105 chromosome 1 open reading frame 105
C3 complement component 3
CARF calcium responsive transcription factor
CCDC106 coiled-coil domain containing 106
CCL27 chemokine (C-C motif) ligand 27
CCNO cyclin O
CD101 CD101 molecule
CDHR2 cadherin-related family member 2
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CISH cytokine inducible SH2-containing protein
CNGB3 cyclic nucleotide gated channel beta 3
CRYGC crystallin, gamma C
CSF1R colony stimulating factor 1 receptor
DDN dendrin
DEPTOR DEP domain containing MTOR-interacting protein
DGKE diacylglycerol kinase, epsilon 64kDa
DPF3 D4, zinc and double PHD fingers, family 3
ELMO3 engulfment and cell motility 3
EPHX2 epoxide hydrolase 2, cytoplasmic
F3 coagulation factor III (thromboplastin, tissue factor)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FRMD1 FERM domain containing 1
GAL3ST4 galactose-3-O-sulfotransferase 4
GPR19 G protein-coupled receptor 19
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRAMD1C GRAM domain containing 1C
GRWD1 glutamate-rich WD repeat containing 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H3C histone cluster 1, H3c
HIST1H3G histone cluster 1, H3g
HIST1H4C histone cluster 1, H4c
HIST1H4D histone cluster 1, H4d
HIST2H2AA3 histone cluster 2, H2aa3
HOXA4 homeobox A4
HOXA6 homeobox A6
HPN hepsin
IL33 interleukin 33
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LIMD2 LIM domain containing 2
LINC00260 long intergenic non-protein coding RNA 260
LOC257152 uncharacterized LOC257152
LRRK1 leucine-rich repeat kinase 1
LTC4S leukotriene C4 synthase
LY86 lymphocyte antigen 86
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MFAP2 microfibrillar-associated protein 2
MGP matrix Gla protein
MNX1 motor neuron and pancreas homeobox 1
MTHFSD methenyltetrahydrofolate synthetase domain containing
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYL5 myosin, light chain 5, regulatory
NACA2 nascent polypeptide-associated complex alpha subunit 2
NCS1 neuronal calcium sensor 1
NEK11 NIMA-related kinase 11
NKX3-2 NK3 homeobox 2
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NPIPB15 nuclear pore complex interacting protein family, member B15
PADI1 peptidyl arginine deiminase, type I
PCDHA9 protocadherin alpha 9
PLEKHS1 pleckstrin homology domain containing, family S member 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RIBC2 RIB43A domain with coiled-coils 2
RNF2 ring finger protein 2
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPGR retinitis pigmentosa GTPase regulator
SAA4 serum amyloid A4, constitutive
SCML2 sex comb on midleg-like 2 (Drosophila)
SELL selectin L
SGK2 serum/glucocorticoid regulated kinase 2
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC25A40 solute carrier family 25, member 40
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SYT17 synaptotagmin XVII
TCTN2 tectonic family member 2
TM6SF1 transmembrane 6 superfamily member 1
TNS2 tensin 2
TRPV6 transient receptor potential cation channel, subfamily V, member 6
WFDC2 WAP four-disulfide core domain 2
ZNF492 zinc finger protein 492
ZNF639 zinc finger protein 639