oxybutynin-7126 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the oxybutynin-7126 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ACE angiotensin I converting enzyme
ADCY1 adenylate cyclase 1 (brain)
ADRBK1 adrenergic, beta, receptor kinase 1
AKAP7 A kinase (PRKA) anchor protein 7
AKAP8L A kinase (PRKA) anchor protein 8-like
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APH1B APH1B gamma secretase subunit
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ASF1A anti-silencing function 1A histone chaperone
ATF3 activating transcription factor 3
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BIN1 bridging integrator 1
BTF3P12 basic transcription factor 3 pseudogene 12
C19ORF66 chromosome 19 open reading frame 66
CA5B carbonic anhydrase VB, mitochondrial
CASP1 caspase 1, apoptosis-related cysteine peptidase
CDH8 cadherin 8, type 2
CSE1L CSE1 chromosome segregation 1-like (yeast)
CTSO cathepsin O
CYHR1 cysteine/histidine-rich 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DTNA dystrobrevin, alpha
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EMX1 empty spiracles homeobox 1
ERAP1 endoplasmic reticulum aminopeptidase 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ESRRA estrogen-related receptor alpha
EWSR1 EWS RNA-binding protein 1
FMO5 flavin containing monooxygenase 5
FYN FYN proto-oncogene, Src family tyrosine kinase
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPX2 glutathione peroxidase 2
HOMER2 homer scaffolding protein 2
HUS1 HUS1 checkpoint homolog (S. pombe)
IFI6 interferon, alpha-inducible protein 6
IFIH1 interferon induced with helicase C domain 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IGSF3 immunoglobulin superfamily, member 3
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
KIF1A kinesin family member 1A
KIF5C kinesin family member 5C
KRT34 keratin 34, type I
LAD1 ladinin 1
LAMP1 lysosomal-associated membrane protein 1
LARP4B La ribonucleoprotein domain family, member 4B
LIG3 ligase III, DNA, ATP-dependent
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MCM3AP minichromosome maintenance complex component 3 associated protein
MCMBP minichromosome maintenance complex binding protein
METTL3 methyltransferase like 3
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MRPS14 mitochondrial ribosomal protein S14
MTUS1 microtubule associated tumor suppressor 1
MVK mevalonate kinase
MX1 MX dynamin-like GTPase 1
MYB v-myb avian myeloblastosis viral oncogene homolog
NCOA2 nuclear receptor coactivator 2
NF1 neurofibromin 1
NOP14-AS1 NOP14 antisense RNA 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OASL 2'-5'-oligoadenylate synthetase-like
OVGP1 oviductal glycoprotein 1, 120kDa
PAIP2B poly(A) binding protein interacting protein 2B
PBX2 pre-B-cell leukemia homeobox 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE12 phosphodiesterase 12
PDLIM7 PDZ and LIM domain 7 (enigma)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PNRC1 proline-rich nuclear receptor coactivator 1
POMT2 protein-O-mannosyltransferase 2
RANBP3 RAN binding protein 3
RIN1 Ras and Rab interactor 1
ROR1 receptor tyrosine kinase-like orphan receptor 1
RPL14 ribosomal protein L14
SAMD9 sterile alpha motif domain containing 9
SCAPER S-phase cyclin A-associated protein in the ER
SCARA3 scavenger receptor class A, member 3
SF3B3 splicing factor 3b, subunit 3, 130kDa
SIPA1L3 signal-induced proliferation-associated 1 like 3
SIRT3 sirtuin 3
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SLC35G2 solute carrier family 35, member G2
SND1-IT1 SND1 intronic transcript 1
STK17B serine/threonine kinase 17b
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TMC7 transmembrane channel-like 7
TSC22D4 TSC22 domain family, member 4
VPRBP Vpr (HIV-1) binding protein
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZFHX3 zinc finger homeobox 3

decreased expression

Symbol Name
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADGRF1 adhesion G protein-coupled receptor F1
ANXA10 annexin A10
ARMC6 armadillo repeat containing 6
ATG14 autophagy related 14
BRPF1 bromodomain and PHD finger containing, 1
CADPS2 Ca++-dependent secretion activator 2
CAPN5 calpain 5
CBX7 chromobox homolog 7
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CHPF chondroitin polymerizing factor
CHUK conserved helix-loop-helix ubiquitous kinase
COG4 component of oligomeric golgi complex 4
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DHRS11 dehydrogenase/reductase (SDR family) member 11
DNAAF2 dynein, axonemal, assembly factor 2
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DPY19L2P2 DPY19L2 pseudogene 2
EDC4 enhancer of mRNA decapping 4
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ERCC2 excision repair cross-complementation group 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FCHO1 FCH domain only 1
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GDAP1 ganglioside induced differentiation associated protein 1
GPALPP1 GPALPP motifs containing 1
HOXC10 homeobox C10
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IPO8 importin 8
KIAA0355 KIAA0355
KIAA0513 KIAA0513
KIAA0556 KIAA0556
KIFC1 kinesin family member C1
KISS1 KiSS-1 metastasis-suppressor
LZTR1 leucine-zipper-like transcription regulator 1
MAN2B2 mannosidase, alpha, class 2B, member 2
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MCRS1 microspherule protein 1
MCTP1 multiple C2 domains, transmembrane 1
NFE2L3 nuclear factor, erythroid 2-like 3
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NHLRC2 NHL repeat containing 2
NR3C2 nuclear receptor subfamily 3, group C, member 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae)
PCSK7 proprotein convertase subtilisin/kexin type 7
PILRB paired immunoglobin-like type 2 receptor beta
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD3 phospholipase D family, member 3
PLSCR4 phospholipid scramblase 4
PMM2 phosphomannomutase 2
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLM polymerase (DNA directed), mu
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PTBP2 polypyrimidine tract binding protein 2
RNF44 ring finger protein 44
RPAP2 RNA polymerase II associated protein 2
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCAMP4 secretory carrier membrane protein 4
SETD1B SET domain containing 1B
SFXN1 sideroflexin 1
SH3GL1 SH3-domain GRB2-like 1
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLMO2 slowmo homolog 2 (Drosophila)
SPAG16 sperm associated antigen 16
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
STBD1 starch binding domain 1
STK16 serine/threonine kinase 16
STK25 serine/threonine kinase 25
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TM7SF2 transmembrane 7 superfamily member 2
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM104 transmembrane protein 104
TMEM254 transmembrane protein 254
TRIM52 tripartite motif containing 52
TUBA3D tubulin, alpha 3d
ULK1 unc-51 like autophagy activating kinase 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR18 WD repeat domain 18
WDR76 WD repeat domain 76
XPC xeroderma pigmentosum, complementation group C
XYLT2 xylosyltransferase II
ZC3H7A zinc finger CCCH-type containing 7A
ZFP36 ZFP36 ring finger protein
ZNF273 zinc finger protein 273
ZNF385D zinc finger protein 385D
ZNF552 zinc finger protein 552
ZNF813 zinc finger protein 813
ZNF84 zinc finger protein 84
ZXDC ZXD family zinc finger C