oxprenolol-6145 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the oxprenolol-6145 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACAN aggrecan
ACRV1 acrosomal vesicle protein 1
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
AHSG alpha-2-HS-glycoprotein
ANGEL2 angel homolog 2 (Drosophila)
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ATF7IP activating transcription factor 7 interacting protein
ATP9B ATPase, class II, type 9B
BBS9 Bardet-Biedl syndrome 9
CD84 CD84 molecule
CDH16 cadherin 16, KSP-cadherin
CEP250 centrosomal protein 250kDa
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CLIC5 chloride intracellular channel 5
CNGB3 cyclic nucleotide gated channel beta 3
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CNTD2 cyclin N-terminal domain containing 2
CRYGC crystallin, gamma C
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DHRS12 dehydrogenase/reductase (SDR family) member 12
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EFNA3 ephrin-A3
EFS embryonal Fyn-associated substrate
ETV1 ets variant 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GEMIN7 gem (nuclear organelle) associated protein 7
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GJB4 gap junction protein, beta 4, 30.3kDa
GRAP GRB2-related adaptor protein
GRIP2 glutamate receptor interacting protein 2
GSTT1 glutathione S-transferase theta 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HIST1H2BM histone cluster 1, H2bm
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
INSL4 insulin-like 4 (placenta)
IRF4 interferon regulatory factor 4
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3
KDM4B lysine (K)-specific demethylase 4B
KDSR 3-ketodihydrosphingosine reductase
KIF5C kinesin family member 5C
KLHL3 kelch-like family member 3
KRT9 keratin 9, type I
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LIMS2 LIM and senescent cell antigen-like domains 2
LRP1 low density lipoprotein receptor-related protein 1
MAL mal, T-cell differentiation protein
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MBD2 methyl-CpG binding domain protein 2
MBNL2 muscleblind-like splicing regulator 2
MINK1 misshapen-like kinase 1
MRPL41 mitochondrial ribosomal protein L41
MUC2 mucin 2, oligomeric mucus/gel-forming
MYCNOS MYCN opposite strand
NPR1 natriuretic peptide receptor 1
OR2H2 olfactory receptor, family 2, subfamily H, member 2
OSBPL10 oxysterol binding protein-like 10
PAX4 paired box 4
PCDHB1 protocadherin beta 1
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PER3 period circadian clock 3
PKP1 plakophilin 1
PRLR prolactin receptor
RPH3A rabphilin 3A
RYR1 ryanodine receptor 1 (skeletal)
SAMD14 sterile alpha motif domain containing 14
SCUBE2 signal peptide, CUB domain, EGF-like 2
SIX2 SIX homeobox 2
SLAMF7 SLAM family member 7
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMAD3 SMAD family member 3
SMYD2 SET and MYND domain containing 2
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1)
SPON1 spondin 1, extracellular matrix protein
STAB1 stabilin 1
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TBC1D19 TBC1 domain family, member 19
TCF4 transcription factor 4
THAP9 THAP domain containing 9
TNK1 tyrosine kinase, non-receptor, 1
TPMT thiopurine S-methyltransferase
TRIM10 tripartite motif containing 10
UBE3A ubiquitin protein ligase E3A
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
USP22 ubiquitin specific peptidase 22
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WSCD1 WSC domain containing 1
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF3 zinc finger protein 3

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
AIM2 absent in melanoma 2
AKTIP AKT interacting protein
ARG1 arginase 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
C21ORF91 chromosome 21 open reading frame 91
C22ORF29 chromosome 22 open reading frame 29
C2CD2 C2 calcium-dependent domain containing 2
CAMKMT calmodulin-lysine N-methyltransferase
CCRL2 chemokine (C-C motif) receptor-like 2
CD320 CD320 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CDK3 cyclin-dependent kinase 3
CEP97 centrosomal protein 97kDa
CHM choroideremia (Rab escort protein 1)
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
CRELD1 cysteine-rich with EGF-like domains 1
CTNNBIP1 catenin, beta interacting protein 1
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EFTUD1 elongation factor Tu GTP binding domain containing 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FJX1 four jointed box 1 (Drosophila)
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GCH1 GTP cyclohydrolase 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR63 G protein-coupled receptor 63
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2AM histone cluster 1, H2am
HIST1H2BI histone cluster 1, H2bi
HIST1H2BN histone cluster 1, H2bn
HIST1H3H histone cluster 1, H3h
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HP haptoglobin
IFNAR1 interferon (alpha, beta and omega) receptor 1
INHBE inhibin, beta E
IRAK4 interleukin-1 receptor-associated kinase 4
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0556 KIAA0556
MAGEF1 melanoma antigen family F1
MCOLN1 mucolipin 1
MILR1 mast cell immunoglobulin-like receptor 1
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MKS1 Meckel syndrome, type 1
MTMR12 myotubularin related protein 12
NDE1 nudE neurodevelopment protein 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NSUN6 NOP2/Sun domain family, member 6
PHC1 polyhomeotic homolog 1 (Drosophila)
PMP22 peripheral myelin protein 22
PPAP2A phosphatidic acid phosphatase type 2A
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PRAF2 PRA1 domain family, member 2
PRICKLE3 prickle homolog 3 (Drosophila)
PRKX protein kinase, X-linked
PYGB phosphorylase, glycogen; brain
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RNF126P1 ring finger protein 126 pseudogene 1
RPL13P5 ribosomal protein L13 pseudogene 5
RPL23AP32 ribosomal protein L23a pseudogene 32
SCAI suppressor of cancer cell invasion
SCAMP4 secretory carrier membrane protein 4
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SERGEF secretion regulating guanine nucleotide exchange factor
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SH2D3C SH2 domain containing 3C
SLC44A1 solute carrier family 44 (choline transporter), member 1
SNHG20 small nucleolar RNA host gene 20
SOX12 SRY (sex determining region Y)-box 12
SPON2 spondin 2, extracellular matrix protein
STBD1 starch binding domain 1
TAS2R10 taste receptor, type 2, member 10
TCTN1 tectonic family member 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THBS3 thrombospondin 3
THBS4 thrombospondin 4
THRAP3 thyroid hormone receptor associated protein 3
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TMEM242 transmembrane protein 242
TMUB2 transmembrane and ubiquitin-like domain containing 2
TSPAN32 tetraspanin 32
TTC26 tetratricopeptide repeat domain 26
UEVLD UEV and lactate/malate dehyrogenase domains
UPK3A uroplakin 3A
USP6 ubiquitin specific peptidase 6
ZBTB38 zinc finger and BTB domain containing 38
ZBTB6 zinc finger and BTB domain containing 6
ZNF254 zinc finger protein 254
ZNF280D zinc finger protein 280D
ZNF529 zinc finger protein 529
ZNF667 zinc finger protein 667
ZNF768 zinc finger protein 768
ZNF862 zinc finger protein 862