oxolinic acid-5094 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the oxolinic acid-5094 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTA1 actin, alpha 1, skeletal muscle
AFF1 AF4/FMR2 family, member 1
APOC1 apolipoprotein C-I
ATF6B activating transcription factor 6 beta
C14ORF93 chromosome 14 open reading frame 93
C15ORF39 chromosome 15 open reading frame 39
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CD58 CD58 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CPB1 carboxypeptidase B1 (tissue)
CPEB3 cytoplasmic polyadenylation element binding protein 3
CSHL1 chorionic somatomammotropin hormone-like 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYTH3 cytohesin 3
DAGLA diacylglycerol lipase, alpha
DDN dendrin
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DNAH17 dynein, axonemal, heavy chain 17
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DTX2 deltex 2, E3 ubiquitin ligase
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
FAM13C family with sequence similarity 13, member C
FCMR Fc fragment of IgM receptor
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FSCN3 fascin actin-bundling protein 3, testicular
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GPR1 G protein-coupled receptor 1
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIP2 glutamate receptor interacting protein 2
HIP1 huntingtin interacting protein 1
HIPK3 homeodomain interacting protein kinase 3
HRH2 histamine receptor H2
ICA1 islet cell autoantigen 1, 69kDa
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IGLJ3 immunoglobulin lambda joining 3
INSR insulin receptor
KCNMB2 potassium channel subfamily M regulatory beta subunit 2
KDM4C lysine (K)-specific demethylase 4C
KDM6B lysine (K)-specific demethylase 6B
KIAA0368 KIAA0368
LMNA lamin A/C
LMO7 LIM domain 7
LOC399491
LOX lysyl oxidase
LPAR4 lysophosphatidic acid receptor 4
LRRC1 leucine rich repeat containing 1
LST1 leukocyte specific transcript 1
MASP2 mannan-binding lectin serine peptidase 2
MBD2 methyl-CpG binding domain protein 2
N4BP2L1 NEDD4 binding protein 2-like 1
NEUROD1 neuronal differentiation 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NID2 nidogen 2 (osteonidogen)
NOP14-AS1 NOP14 antisense RNA 1
NRP2 neuropilin 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
ODF1 outer dense fiber of sperm tails 1
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PADI1 peptidyl arginine deiminase, type I
PCOLCE procollagen C-endopeptidase enhancer
PDE10A phosphodiesterase 10A
PDGFA platelet-derived growth factor alpha polypeptide
PHOX2B paired-like homeobox 2b
PIDD1 p53-induced death domain protein 1
PLEK pleckstrin
PPIAL4A peptidylprolyl isomerase A (cyclophilin A)-like 4A
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PQBP1 polyglutamine binding protein 1
PRELP proline/arginine-rich end leucine-rich repeat protein
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
PYY peptide YY
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAPSN receptor-associated protein of the synapse
RIBC2 RIB43A domain with coiled-coils 2
SARM1 sterile alpha and TIR motif containing 1
SKIL SKI-like proto-oncogene
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC45A2 solute carrier family 45, member 2
SOGA1 suppressor of glucose, autophagy associated 1
SORBS1 sorbin and SH3 domain containing 1
SPRED2 sprouty-related, EVH1 domain containing 2
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAB2 stabilin 2
STRN striatin, calmodulin binding protein
SUN1 Sad1 and UNC84 domain containing 1
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TGFA transforming growth factor, alpha
TJAP1 tight junction associated protein 1 (peripheral)
TMEM59L transmembrane protein 59-like
TOM1 target of myb1 (chicken)
TTLL5 tubulin tyrosine ligase-like family member 5
UPB1 ureidopropionase, beta
ZBTB43 zinc finger and BTB domain containing 43
ZFHX3 zinc finger homeobox 3
ZNF268 zinc finger protein 268
ZNF528 zinc finger protein 528

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACVR2B activin A receptor, type IIB
ADGRB2 adhesion G protein-coupled receptor B2
ANP32A-IT1 ANP32A intronic transcript 1
APOLD1 apolipoprotein L domain containing 1
ARL15 ADP-ribosylation factor-like 15
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BOLA1 bolA family member 1
C14ORF105 chromosome 14 open reading frame 105
CCDC85C coiled-coil domain containing 85C
CCP110 centriolar coiled coil protein 110kDa
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CENPJ centromere protein J
CIR1 corepressor interacting with RBPJ, 1
CLCN6 chloride channel, voltage-sensitive 6
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
ELOVL4 ELOVL fatty acid elongase 4
ETNK2 ethanolamine kinase 2
FKBP1B FK506 binding protein 1B, 12.6 kDa
FRS2 fibroblast growth factor receptor substrate 2
GAREM GRB2 associated, regulator of MAPK1
GHR growth hormone receptor
GLTSCR1 glioma tumor suppressor candidate region gene 1
GRAMD4 GRAM domain containing 4
HIST1H1E histone cluster 1, H1e
HIST1H2AM histone cluster 1, H2am
HIST1H2BF histone cluster 1, H2bf
HIST1H2BJ histone cluster 1, H2bj
HLX H2.0-like homeobox
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXA4 homeobox A4
HYAL2 hyaluronoglucosaminidase 2
IFI6 interferon, alpha-inducible protein 6
IFNA2 interferon, alpha 2
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA0754 KIAA0754
KLHL36 kelch-like family member 36
KLK5 kallikrein-related peptidase 5
KLK6 kallikrein-related peptidase 6
LIFR leukemia inhibitory factor receptor alpha
LIN37 lin-37 DREAM MuvB core complex component
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MATN3 matrilin 3
MB myoglobin
MFGE8 milk fat globule-EGF factor 8 protein
MFSD11 major facilitator superfamily domain containing 11
MGC12488
MUC3A mucin 3A, cell surface associated
MXRA8 matrix-remodelling associated 8
NABP1 nucleic acid binding protein 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NOD1 nucleotide-binding oligomerization domain containing 1
NPM3 nucleophosmin/nucleoplasmin 3
NR1H3 nuclear receptor subfamily 1, group H, member 3
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
ORAI3 ORAI calcium release-activated calcium modulator 3
OSR2 odd-skipped related transciption factor 2
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PACS1 phosphofurin acidic cluster sorting protein 1
PARM1 prostate androgen-regulated mucin-like protein 1
PHKG2 phosphorylase kinase, gamma 2 (testis)
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RBMS3 RNA binding motif, single stranded interacting protein 3
SAYSD1 SAYSVFN motif domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SDC3 syndecan 3
SETD8 SET domain containing (lysine methyltransferase) 8
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC46A3 solute carrier family 46, member 3
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SOX12 SRY (sex determining region Y)-box 12
SPAG4 sperm associated antigen 4
SSBP3 single stranded DNA binding protein 3
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
THBS3 thrombospondin 3
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRIM25 tripartite motif containing 25
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TTLL1 tubulin tyrosine ligase-like family member 1
YOD1 YOD1 deubiquitinase
ZBTB33 zinc finger and BTB domain containing 33
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF280D zinc finger protein 280D
ZNF415 zinc finger protein 415
ZNF446 zinc finger protein 446
ZNF671 zinc finger protein 671
ZNF711 zinc finger protein 711
ZNF76 zinc finger protein 76