oxolinic acid-2103 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the oxolinic acid-2103 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACTN4 actinin, alpha 4
ADAP2 ArfGAP with dual PH domains 2
ANKMY1 ankyrin repeat and MYND domain containing 1
ANKRD12 ankyrin repeat domain 12
AP2B1 adaptor-related protein complex 2, beta 1 subunit
ARID1A AT rich interactive domain 1A (SWI-like)
ASTN2 astrotactin 2
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATXN3 ataxin 3
BAX BCL2-associated X protein
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C11ORF63 chromosome 11 open reading frame 63
CALD1 caldesmon 1
CASP2 caspase 2, apoptosis-related cysteine peptidase
CLEC4A C-type lectin domain family 4, member A
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DAPK3 death-associated protein kinase 3
DSC1 desmocollin 1
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FNDC4 fibronectin type III domain containing 4
FOXA2 forkhead box A2
GAREM GRB2 associated, regulator of MAPK1
GLE1 GLE1 RNA export mediator
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HOXA11 homeobox A11
HOXC10 homeobox C10
HPS1 Hermansky-Pudlak syndrome 1
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
INO80B INO80 complex subunit B
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IQCE IQ motif containing E
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
JUND jun D proto-oncogene
KDM5A lysine (K)-specific demethylase 5A
KIAA1462 KIAA1462
KLF3 Kruppel-like factor 3 (basic)
LARGE like-glycosyltransferase
LDB1 LIM domain binding 1
LEF1 lymphoid enhancer-binding factor 1
LRP3 low density lipoprotein receptor-related protein 3
LTC4S leukotriene C4 synthase
LYPD3 LY6/PLAUR domain containing 3
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MBD2 methyl-CpG binding domain protein 2
MCC mutated in colorectal cancers
METTL5 methyltransferase like 5
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MUC3B mucin 3B, cell surface associated
MYO7A myosin VIIA
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NIPAL2 NIPA-like domain containing 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PALMD palmdelphin
PARVA parvin, alpha
PCNX pecanex homolog (Drosophila)
PDAP1 PDGFA associated protein 1
PF4 platelet factor 4
PLXNC1 plexin C1
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
RAB31 RAB31, member RAS oncogene family
RARS arginyl-tRNA synthetase
RBM3 RNA binding motif (RNP1, RRM) protein 3
REST RE1-silencing transcription factor
RGS10 regulator of G-protein signaling 10
RNF2 ring finger protein 2
RPL10 ribosomal protein L10
RPS4Y1 ribosomal protein S4, Y-linked 1
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SENP6 SUMO1/sentrin specific peptidase 6
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLITRK5 SLIT and NTRK-like family, member 5
SOBP sine oculis binding protein homolog (Drosophila)
TAT tyrosine aminotransferase
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THRAP3 thyroid hormone receptor associated protein 3
TLE4 transducin-like enhancer of split 4
VASP vasodilator-stimulated phosphoprotein
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
YIPF4 Yip1 domain family, member 4
ZBTB22 zinc finger and BTB domain containing 22
ZC2HC1C zinc finger, C2HC-type containing 1C
ZFR zinc finger RNA binding protein
ZFX zinc finger protein, X-linked
ZHX3 zinc fingers and homeoboxes 3
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABHD17B abhydrolase domain containing 17B
ACTG2 actin, gamma 2, smooth muscle, enteric
AEN apoptosis enhancing nuclease
ALS2CL ALS2 C-terminal like
ANXA2P3 annexin A2 pseudogene 3
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARL14 ADP-ribosylation factor-like 14
ATF7IP2 activating transcription factor 7 interacting protein 2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BDH1 3-hydroxybutyrate dehydrogenase, type 1
C19ORF54 chromosome 19 open reading frame 54
C9ORF3 chromosome 9 open reading frame 3
CA5BP1 carbonic anhydrase VB pseudogene 1
CABIN1 calcineurin binding protein 1
CAMTA2 calmodulin binding transcription activator 2
CHKB choline kinase beta
CLASRP CLK4-associating serine/arginine rich protein
CLCN5 chloride channel, voltage-sensitive 5
CLEC2B C-type lectin domain family 2, member B
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DEAF1 DEAF1 transcription factor
EFNA3 ephrin-A3
EPHB6 EPH receptor B6
ESM1 endothelial cell-specific molecule 1
FAM184A family with sequence similarity 184, member A
FAM53B family with sequence similarity 53, member B
FBXL7 F-box and leucine-rich repeat protein 7
GJC1 gap junction protein, gamma 1, 45kDa
GOLGA8B golgin A8 family, member B
GSDMD gasdermin D
GSR glutathione reductase
HMHA1 histocompatibility (minor) HA-1
HYI hydroxypyruvate isomerase (putative)
IL17RA interleukin 17 receptor A
IREB2 iron-responsive element binding protein 2
IRF2 interferon regulatory factor 2
KIAA0556 KIAA0556
KIAA0894 KIAA0894 protein
KIAA1549L KIAA1549-like
LMBR1L limb development membrane protein 1-like
LRRC61 leucine rich repeat containing 61
MAGEA6 melanoma antigen family A6
MFSD10 major facilitator superfamily domain containing 10
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
ODF2 outer dense fiber of sperm tails 2
OLFML3 olfactomedin-like 3
OVGP1 oviductal glycoprotein 1, 120kDa
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PARD6A par-6 family cell polarity regulator alpha
PARM1 prostate androgen-regulated mucin-like protein 1
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDLIM2 PDZ and LIM domain 2 (mystique)
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLXNA3 plexin A3
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRAME preferentially expressed antigen in melanoma
PRR15L proline rich 15-like
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RAB33B RAB33B, member RAS oncogene family
RANBP17 RAN binding protein 17
RFX7 regulatory factor X, 7
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RIN1 Ras and Rab interactor 1
SAMD9 sterile alpha motif domain containing 9
SETD6 SET domain containing 6
SHPK sedoheptulokinase
SHROOM2 shroom family member 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLC46A3 solute carrier family 46, member 3
SPEG SPEG complex locus
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STAG3 stromal antigen 3
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STBD1 starch binding domain 1
STK16 serine/threonine kinase 16
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBC1D19 TBC1 domain family, member 19
TEX40 testis expressed 40
TH tyrosine hydroxylase
THBS3 thrombospondin 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM183A transmembrane protein 183A
TRIM45 tripartite motif containing 45
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TTC26 tetratricopeptide repeat domain 26
USP36 ubiquitin specific peptidase 36
ZBED8 zinc finger, BED-type containing 8
ZBTB25 zinc finger and BTB domain containing 25
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF16 zinc finger protein 16
ZNF189 zinc finger protein 189
ZNF324 zinc finger protein 324
ZNF862 zinc finger protein 862