oxolinic acid-1419 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the oxolinic acid-1419 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
ADAM10 ADAM metallopeptidase domain 10
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
ALDOB aldolase B, fructose-bisphosphate
ANKRD12 ankyrin repeat domain 12
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARSB arylsulfatase B
ASF1A anti-silencing function 1A histone chaperone
ATAD2B ATPase family, AAA domain containing 2B
ATG4B autophagy related 4B, cysteine peptidase
ATP11A ATPase, class VI, type 11A
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
AURKA aurora kinase A
BBIP1 BBSome interacting protein 1
C21ORF91 chromosome 21 open reading frame 91
CAND1 cullin-associated and neddylation-dissociated 1
CCR2 chemokine (C-C motif) receptor 2
CD84 CD84 molecule
CD86 CD86 molecule
CDC42SE1 CDC42 small effector 1
CDC5L cell division cycle 5-like
CENPI centromere protein I
COX11 COX11 cytochrome c oxidase copper chaperone
CRYBG3 beta-gamma crystallin domain containing 3
CUL4B cullin 4B
CUL5 cullin 5
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EFR3B EFR3 homolog B (S. cerevisiae)
EIF5B eukaryotic translation initiation factor 5B
ETNK1 ethanolamine kinase 1
FGFR2 fibroblast growth factor receptor 2
GHRHR growth hormone releasing hormone receptor
GIN1 gypsy retrotransposon integrase 1
GLRX glutaredoxin (thioltransferase)
GRSF1 G-rich RNA sequence binding factor 1
HFE hemochromatosis
HIST1H4J histone cluster 1, H4j
HMGN5 high mobility group nucleosome binding domain 5
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IDI2-AS1 IDI2 antisense RNA 1
IER3IP1 immediate early response 3 interacting protein 1
JAK2 Janus kinase 2
KLF6 Kruppel-like factor 6
LDOC1 leucine zipper, down-regulated in cancer 1
LMAN1 lectin, mannose-binding, 1
MAGOH2P mago-nashi homolog 2, pseudogene
MTMR12 myotubularin related protein 12
MTMR3 myotubularin related protein 3
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NMD3 NMD3 ribosome export adaptor
NOP16 NOP16 nucleolar protein
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
OPHN1 oligophrenin 1
PARVA parvin, alpha
PBX2 pre-B-cell leukemia homeobox 2
PCGF2 polycomb group ring finger 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PDCD2 programmed cell death 2
PGK1 phosphoglycerate kinase 1
PLIN2 perilipin 2
PMCH pro-melanin-concentrating hormone
PPP1R7 protein phosphatase 1, regulatory subunit 7
PRRC2C proline-rich coiled-coil 2C
RAB2A RAB2A, member RAS oncogene family
RHEB Ras homolog enriched in brain
RPAIN RPA interacting protein
RPL14 ribosomal protein L14
RPL27A ribosomal protein L27a
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPLP2 ribosomal protein, large, P2
RPS11 ribosomal protein S11
SH3GL3 SH3-domain GRB2-like 3
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SRSF1 serine/arginine-rich splicing factor 1
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
SUB1 SUB1 homolog (S. cerevisiae)
SYNJ2 synaptojanin 2
TCP11L1 t-complex 11, testis-specific-like 1
TCTN2 tectonic family member 2
TFG TRK-fused gene
TMSB4Y thymosin beta 4, Y-linked
TPMT thiopurine S-methyltransferase
TRAM1 translocation associated membrane protein 1
TRIM25 tripartite motif containing 25
TXN thioredoxin
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VDAC3 voltage-dependent anion channel 3
YLPM1 YLP motif containing 1
ZNF747 zinc finger protein 747
ZNF770 zinc finger protein 770

decreased expression

Symbol Name
ABHD17A abhydrolase domain containing 17A
ADGRE5 adhesion G protein-coupled receptor E5
ADRM1 adhesion regulating molecule 1
ANXA6 annexin A6
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2
ARFIP2 ADP-ribosylation factor interacting protein 2
ARHGAP4 Rho GTPase activating protein 4
ASB6 ankyrin repeat and SOCS box containing 6
ASL argininosuccinate lyase
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
AZU1 azurocidin 1
BANF1 barrier to autointegration factor 1
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BCL7C B-cell CLL/lymphoma 7C
BCORL1 BCL6 corepressor-like 1
BRPF1 bromodomain and PHD finger containing, 1
C1ORF216 chromosome 1 open reading frame 216
CAPN15 calpain 15
CD151 CD151 molecule (Raph blood group)
CD81 CD81 molecule
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CLDN15 claudin 15
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CNPY3 canopy FGF signaling regulator 3
CSK c-src tyrosine kinase
CYC1 cytochrome c-1
DGKZ diacylglycerol kinase, zeta
DNM1 dynamin 1
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3
DUS1L dihydrouridine synthase 1-like (S. cerevisiae)
E2F8 E2F transcription factor 8
EFHD2 EF-hand domain family, member D2
ELANE elastase, neutrophil expressed
FAM222B family with sequence similarity 222, member B
FES FES proto-oncogene, tyrosine kinase
GBAP1 glucosidase, beta, acid pseudogene 1
GMPPB GDP-mannose pyrophosphorylase B
IFITM3 interferon induced transmembrane protein 3
IFRD2 interferon-related developmental regulator 2
IL2RG interleukin 2 receptor, gamma
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
KIF21B kinesin family member 21B
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MACROD1 MACRO domain containing 1
MAN2C1 mannosidase, alpha, class 2C, member 1
MAP3K3 mitogen-activated protein kinase kinase kinase 3
METTL22 methyltransferase like 22
MGAM maltase-glucoamylase
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MLF2 myeloid leukemia factor 2
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MOSPD3 motile sperm domain containing 3
MYH9 myosin, heavy chain 9, non-muscle
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit
NELFE negative elongation factor complex member E
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NGRN neugrin, neurite outgrowth associated
NMB neuromedin B
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
NT5DC2 5'-nucleotidase domain containing 2
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
PEF1 penta-EF-hand domain containing 1
PES1 pescadillo ribosomal biogenesis factor 1
PGLS 6-phosphogluconolactonase
PHGDH phosphoglycerate dehydrogenase
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PLK1 polo-like kinase 1
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B
PRTN3 proteinase 3
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RAB4B RAB4B, member RAS oncogene family
RHOG ras homolog family member G
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SAC3D1 SAC3 domain containing 1
SCO2 SCO2 cytochrome c oxidase assembly protein
SEC61B Sec61 beta subunit
SF3B4 splicing factor 3b, subunit 4, 49kDa
SH3GL1 SH3-domain GRB2-like 1
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC2A4RG SLC2A4 regulator
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SNAP29 synaptosomal-associated protein, 29kDa
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
STXBP2 syntaxin binding protein 2
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TECR trans-2,3-enoyl-CoA reductase
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TMEM160 transmembrane protein 160
TMEM177 transmembrane protein 177
TRIM28 tripartite motif containing 28
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSTA3 tissue specific transplantation antigen P35B
UBE2M ubiquitin-conjugating enzyme E2M
UQCRC1 ubiquinol-cytochrome c reductase core protein I
ZBTB48 zinc finger and BTB domain containing 48