oxolamine-4969 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the oxolamine-4969 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
AKAP8L A kinase (PRKA) anchor protein 8-like
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C3 aldo-keto reductase family 1, member C3
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARNT aryl hydrocarbon receptor nuclear translocator
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BMP4 bone morphogenetic protein 4
BMP5 bone morphogenetic protein 5
CCDC64 coiled-coil domain containing 64
CCNO cyclin O
CD58 CD58 molecule
CD6 CD6 molecule
CDK14 cyclin-dependent kinase 14
CHML choroideremia-like (Rab escort protein 2)
CLDN17 claudin 17
CXCR4 chemokine (C-X-C motif) receptor 4
DLG5 discs, large homolog 5 (Drosophila)
DMPK dystrophia myotonica-protein kinase
DNAL4 dynein, axonemal, light chain 4
DOCK5 dedicator of cytokinesis 5
EML2 echinoderm microtubule associated protein like 2
EPHX2 epoxide hydrolase 2, cytoplasmic
FAM131A family with sequence similarity 131, member A
FAM134B family with sequence similarity 134, member B
FKBP8 FK506 binding protein 8, 38kDa
G6PC3 glucose 6 phosphatase, catalytic, 3
GLIPR1 GLI pathogenesis-related 1
GM2A GM2 ganglioside activator
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GRM7 glutamate receptor, metabotropic 7
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HFE hemochromatosis
HIST1H1D histone cluster 1, H1d
HMOX1 heme oxygenase 1
HOMER3 homer scaffolding protein 3
IDS iduronate 2-sulfatase
INHBA inhibin, beta A
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
ITGA8 integrin, alpha 8
KIAA1109 KIAA1109
KLF6 Kruppel-like factor 6
KLHL22 kelch-like family member 22
LTBP4 latent transforming growth factor beta binding protein 4
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYB v-myb avian myeloblastosis viral oncogene homolog
NADK NAD kinase
NF2 neurofibromin 2 (merlin)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NLE1 notchless homolog 1 (Drosophila)
NME5 NME/NM23 family member 5
NPM3 nucleophosmin/nucleoplasmin 3
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUP188 nucleoporin 188kDa
NXN nucleoredoxin
OLFML2A olfactomedin-like 2A
OSGIN1 oxidative stress induced growth inhibitor 1
PCNX pecanex homolog (Drosophila)
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PLCG1 phospholipase C, gamma 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
POM121L9P POM121 transmembrane nucleoporin-like 9, pseudogene
POU2F3 POU class 2 homeobox 3
PP14571 uncharacterized LOC100130449
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
RAB6B RAB6B, member RAS oncogene family
RAD23B RAD23 homolog B (S. cerevisiae)
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBM3 RNA binding motif (RNP1, RRM) protein 3
RBM5 RNA binding motif protein 5
RNF122 ring finger protein 122
RNF6 ring finger protein (C3H2C3 type) 6
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
RTEL1 regulator of telomere elongation helicase 1
S100A2 S100 calcium binding protein A2
SCN10A sodium channel, voltage gated, type X alpha subunit
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SOCS6 suppressor of cytokine signaling 6
SOGA1 suppressor of glucose, autophagy associated 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SRSF5 serine/arginine-rich splicing factor 5
SSX1 synovial sarcoma, X breakpoint 1
TAS2R10 taste receptor, type 2, member 10
TCP11L1 t-complex 11, testis-specific-like 1
THY1 Thy-1 cell surface antigen
TOP3B topoisomerase (DNA) III beta
TPMT thiopurine S-methyltransferase
TRIM16 tripartite motif containing 16
TTC9 tetratricopeptide repeat domain 9
UHRF1BP1L UHRF1 binding protein 1-like
VEGFB vascular endothelial growth factor B
WSB1 WD repeat and SOCS box containing 1
XYLB xylulokinase homolog (H. influenzae)
ZC3H13 zinc finger CCCH-type containing 13

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALOX15 arachidonate 15-lipoxygenase
ARMCX2 armadillo repeat containing, X-linked 2
ASB9 ankyrin repeat and SOCS box containing 9
ATF7IP2 activating transcription factor 7 interacting protein 2
ATP13A2 ATPase type 13A2
BIRC3 baculoviral IAP repeat containing 3
BTF3P12 basic transcription factor 3 pseudogene 12
C17ORF70 chromosome 17 open reading frame 70
CA11 carbonic anhydrase XI
CA5BP1 carbonic anhydrase VB pseudogene 1
CLDN15 claudin 15
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COPS7B COP9 signalosome subunit 7B
CXADR coxsackie virus and adenovirus receptor
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
EFHD2 EF-hand domain family, member D2
ERCC5 excision repair cross-complementation group 5
FANCE Fanconi anemia, complementation group E
FGD1 FYVE, RhoGEF and PH domain containing 1
FRMD1 FERM domain containing 1
GEMIN8 gem (nuclear organelle) associated protein 8
GFOD1 glucose-fructose oxidoreductase domain containing 1
GPR157 G protein-coupled receptor 157
GPRC5C G protein-coupled receptor, class C, group 5, member C
HIST1H2BO histone cluster 1, H2bo
HIST2H2AA3 histone cluster 2, H2aa3
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXA4 homeobox A4
HOXC10 homeobox C10
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HYI hydroxypyruvate isomerase (putative)
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IL4R interleukin 4 receptor
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIAA0754 KIAA0754
LRP2 low density lipoprotein receptor-related protein 2
LRRC8E leucine rich repeat containing 8 family, member E
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MRPL41 mitochondrial ribosomal protein L41
MSI1 musashi RNA-binding protein 1
MVD mevalonate (diphospho) decarboxylase
MVP major vault protein
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G3 phospholipase A2, group III
PLCD1 phospholipase C, delta 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PPP6R1 protein phosphatase 6, regulatory subunit 1
PRSS53 protease, serine, 53
PSKH1 protein serine kinase H1
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RNF31 ring finger protein 31
RNF39 ring finger protein 39
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPGR retinitis pigmentosa GTPase regulator
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC12A8 solute carrier family 12, member 8
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
STARD13 StAR-related lipid transfer (START) domain containing 13
STEAP1 six transmembrane epithelial antigen of the prostate 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYT17 synaptotagmin XVII
TM7SF3 transmembrane 7 superfamily member 3
TMEM212 transmembrane protein 212
TPCN1 two pore segment channel 1
TRABD TraB domain containing
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSGA10 testis specific, 10
TUBA3C tubulin, alpha 3c
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
USB1 U6 snRNA biogenesis 1
WDR62 WD repeat domain 62
WFDC2 WAP four-disulfide core domain 2
ZDHHC11 zinc finger, DHHC-type containing 11
ZFP69B ZFP69 zinc finger protein B
ZIC3 Zic family member 3
ZNF16 zinc finger protein 16
ZNF205 zinc finger protein 205
ZNF282 zinc finger protein 282
ZNF318 zinc finger protein 318
ZNF329 zinc finger protein 329
ZNF350 zinc finger protein 350
ZNF696 zinc finger protein 696
ZNF862 zinc finger protein 862