oxolamine-3006 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the oxolamine-3006 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ABHD8 abhydrolase domain containing 8
ADAM8 ADAM metallopeptidase domain 8
ADTRP androgen-dependent TFPI-regulating protein
AGMAT agmatine ureohydrolase (agmatinase)
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
AOX1 aldehyde oxidase 1
ARHGAP33 Rho GTPase activating protein 33
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARTN artemin
ATXN2L ataxin 2-like
ATXN3L ataxin 3-like
B9D2 B9 protein domain 2
BDNF brain-derived neurotrophic factor
C10ORF12 chromosome 10 open reading frame 12
C4BPA complement component 4 binding protein, alpha
C9ORF9 chromosome 9 open reading frame 9
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CACNG2 calcium channel, voltage-dependent, gamma subunit 2
CCDC28B coiled-coil domain containing 28B
CD300C CD300c molecule
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CNOT2 CCR4-NOT transcription complex, subunit 2
CORO2B coronin, actin binding protein, 2B
CRAT carnitine O-acetyltransferase
DCHS2 dachsous cadherin-related 2
DFNB31 deafness, autosomal recessive 31
DNAH3 dynein, axonemal, heavy chain 3
DSTYK dual serine/threonine and tyrosine protein kinase
DUSP4 dual specificity phosphatase 4
EDN3 endothelin 3
EGLN3 egl-9 family hypoxia-inducible factor 3
ELOVL2 ELOVL fatty acid elongase 2
EVA1B eva-1 homolog B (C. elegans)
F12 coagulation factor XII (Hageman factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FDPS farnesyl diphosphate synthase
FGF17 fibroblast growth factor 17
FGFR2 fibroblast growth factor receptor 2
FLRT2 fibronectin leucine rich transmembrane protein 2
GABARAPL1 GABA(A) receptor-associated protein like 1
GDAP1 ganglioside induced differentiation associated protein 1
GLP1R glucagon-like peptide 1 receptor
GNAS GNAS complex locus
GPR22 G protein-coupled receptor 22
HIST1H2BC histone cluster 1, H2bc
HIST1H3C histone cluster 1, H3c
HPCA hippocalcin
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IL22 interleukin 22
IL7R interleukin 7 receptor
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIF5A kinesin family member 5A
LAMA4 laminin, alpha 4
LECT1 leukocyte cell derived chemotaxin 1
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
MAP7 microtubule-associated protein 7
MARC1 mitochondrial amidoxime reducing component 1
MATN1 matrilin 1, cartilage matrix protein
MET MET proto-oncogene, receptor tyrosine kinase
MLXIP MLX interacting protein
MPZL1 myelin protein zero-like 1
MYLK myosin light chain kinase
NCR1 natural cytotoxicity triggering receptor 1
NEFM neurofilament, medium polypeptide
NEK11 NIMA-related kinase 11
NOX1 NADPH oxidase 1
PAX2 paired box 2
PDE4B phosphodiesterase 4B, cAMP-specific
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRDM1 PR domain containing 1, with ZNF domain
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
RCE1 Ras converting CAAX endopeptidase 1
RPS28 ribosomal protein S28
SCAMP5 secretory carrier membrane protein 5
SEC14L4 SEC14-like 4 (S. cerevisiae)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC12A8 solute carrier family 12, member 8
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SOX10 SRY (sex determining region Y)-box 10
SPARCL1 SPARC-like 1 (hevin)
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
TAC3 tachykinin 3
TACR1 tachykinin receptor 1
TAPT1 transmembrane anterior posterior transformation 1
TBX5 T-box 5
TIMELESS timeless circadian clock
TMLHE trimethyllysine hydroxylase, epsilon
TNNT3 troponin T type 3 (skeletal, fast)
TPM3 tropomyosin 3
TRIM62 tripartite motif containing 62
VAMP5 vesicle-associated membrane protein 5
XCL1 chemokine (C motif) ligand 1
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARF5 ADP-ribosylation factor 5
ATXN2 ataxin 2
BAK1 BCL2-antagonist/killer 1
BTBD18 BTB (POZ) domain containing 18
C16ORF59 chromosome 16 open reading frame 59
C17ORF70 chromosome 17 open reading frame 70
C3ORF18 chromosome 3 open reading frame 18
C5ORF45 chromosome 5 open reading frame 45
C8ORF44 chromosome 8 open reading frame 44
CCDC85C coiled-coil domain containing 85C
CEP131 centrosomal protein 131kDa
CFAP45 cilia and flagella associated protein 45
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CTPS2 CTP synthase 2
CXCL2 chemokine (C-X-C motif) ligand 2
DGAT1 diacylglycerol O-acyltransferase 1
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DUSP8 dual specificity phosphatase 8
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ECI2 enoyl-CoA delta isomerase 2
ELAC1 elaC ribonuclease Z 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GAREM GRB2 associated, regulator of MAPK1
GIF gastric intrinsic factor (vitamin B synthesis)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPATCH2 G patch domain containing 2
GPATCH2L G patch domain containing 2-like
GPATCH3 G patch domain containing 3
GRAMD1B GRAM domain containing 1B
GSDMD gasdermin D
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HDAC7 histone deacetylase 7
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HIST1H3I histone cluster 1, H3i
HOXA2 homeobox A2
HOXC8 homeobox C8
IBSP integrin-binding sialoprotein
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
INO80D INO80 complex subunit D
KIAA0319L KIAA0319-like
LTA lymphotoxin alpha
MAGEH1 melanoma antigen family H1
MUC2 mucin 2, oligomeric mucus/gel-forming
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NINJ1 ninjurin 1
NPFFR1 neuropeptide FF receptor 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCBP4 poly(rC) binding protein 4
PCDH12 protocadherin 12
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PLEKHS1 pleckstrin homology domain containing, family S member 1
PRDM12 PR domain containing 12
PRF1 perforin 1 (pore forming protein)
PRMT7 protein arginine methyltransferase 7
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
QPRT quinolinate phosphoribosyltransferase
RAB17 RAB17, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RFPL1S RFPL1 antisense RNA 1
RNF126P1 ring finger protein 126 pseudogene 1
RPAP1 RNA polymerase II associated protein 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERINC5 serine incorporator 5
SFRP5 secreted frizzled-related protein 5
SH2D4A SH2 domain containing 4A
SIX3 SIX homeobox 3
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNAI1 snail family zinc finger 1
SPATA20 spermatogenesis associated 20
SPATA2L spermatogenesis associated 2-like
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD13 StAR-related lipid transfer (START) domain containing 13
STATH statherin
STBD1 starch binding domain 1
STX1A syntaxin 1A (brain)
TEP1 telomerase-associated protein 1
TOLLIP toll interacting protein
TPSB2 tryptase beta 2 (gene/pseudogene)
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UPK3A uroplakin 3A
VPREB1 pre-B lymphocyte 1
XYLT2 xylosyltransferase II