oxidized pyrimidine nucleobase lesion dna n-glycosylase activity Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Catalysis of the removal oxidized pyrimidine bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar. The reaction involves formation of a covalent enzyme-pyrimidine base intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site. (Gene Ontology, GO_0000703)
External Link http://amigo.geneontology.org/amigo/term/GO:0000703
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Genes

1 genes performing the oxidized pyrimidine nucleobase lesion dna n-glycosylase activity molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1