oxidized purine nucleobase lesion dna n-glycosylase activity Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme-substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site. (Gene Ontology, GO_0008534)
External Link http://amigo.geneontology.org/amigo/term/GO:0008534
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Genes

2 genes performing the oxidized purine nucleobase lesion dna n-glycosylase activity molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
OGG1 8-oxoguanine DNA glycosylase
RPS3 ribosomal protein S3