oxaprozin-971 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the oxaprozin-971 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
APOLD1 apolipoprotein L domain containing 1
ARMCX1 armadillo repeat containing, X-linked 1
ARNT aryl hydrocarbon receptor nuclear translocator
ASTN2 astrotactin 2
ATF3 activating transcription factor 3
BHLHE40 basic helix-loop-helix family, member e40
BTN2A2 butyrophilin, subfamily 2, member A2
C1ORF105 chromosome 1 open reading frame 105
CACYBP calcyclin binding protein
CCNG2 cyclin G2
CCPG1 cell cycle progression 1
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CEMIP cell migration inducing protein, hyaluronan binding
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CSRP2 cysteine and glycine-rich protein 2
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DIAPH2 diaphanous-related formin 2
DIO2 deiodinase, iodothyronine, type II
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DOCK5 dedicator of cytokinesis 5
DUSP1 dual specificity phosphatase 1
EGR1 early growth response 1
ENO2 enolase 2 (gamma, neuronal)
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAS Fas cell surface death receptor
FBXL2 F-box and leucine-rich repeat protein 2
FBXO38 F-box protein 38
FER fer (fps/fes related) tyrosine kinase
FGFR1OP FGFR1 oncogene partner
FOS FBJ murine osteosarcoma viral oncogene homolog
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GEM GTP binding protein overexpressed in skeletal muscle
GPR87 G protein-coupled receptor 87
HSPA1L heat shock 70kDa protein 1-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
INHBE inhibin, beta E
IQCG IQ motif containing G
JUN jun proto-oncogene
KLHL24 kelch-like family member 24
KPNA5 karyopherin alpha 5 (importin alpha 6)
LDB1 LIM domain binding 1
LMAN1 lectin, mannose-binding, 1
LONP2 lon peptidase 2, peroxisomal
LPCAT3 lysophosphatidylcholine acyltransferase 3
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP1B microtubule-associated protein 1B
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK14 mitogen-activated protein kinase 14
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED6 mediator complex subunit 6
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NBR1 neighbor of BRCA1 gene 1
NDRG2 NDRG family member 2
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NF2 neurofibromin 2 (merlin)
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLD2 phospholipase D2
POLL polymerase (DNA directed), lambda
PRSS16 protease, serine, 16 (thymus)
PSPH phosphoserine phosphatase
RAB32 RAB32, member RAS oncogene family
RAB5A RAB5A, member RAS oncogene family
RAD51 RAD51 recombinase
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic)
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RNF6 ring finger protein (C3H2C3 type) 6
SAT1 spermidine/spermine N1-acetyltransferase 1
SERBP1 SERPINE1 mRNA binding protein 1
SH3BGR SH3 domain binding glutamate-rich protein
SHARPIN SHANK-associated RH domain interactor
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
SNAI2 snail family zinc finger 2
SNAP23 synaptosomal-associated protein, 23kDa
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
SYNGR1 synaptogyrin 1
SYNRG synergin, gamma
TAGLN transgelin
TXNIP thioredoxin interacting protein
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
ZCCHC24 zinc finger, CCHC domain containing 24
ZFX zinc finger protein, X-linked
ZNF141 zinc finger protein 141
ZNF16 zinc finger protein 16
ZNF580 zinc finger protein 580

decreased expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABHD4 abhydrolase domain containing 4
ABLIM3 actin binding LIM protein family, member 3
ACOX3 acyl-CoA oxidase 3, pristanoyl
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
BAK1 BCL2-antagonist/killer 1
BCL9 B-cell CLL/lymphoma 9
CCNT1 cyclin T1
CCP110 centriolar coiled coil protein 110kDa
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CLCN5 chloride channel, voltage-sensitive 5
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COBL cordon-bleu WH2 repeat protein
CPTP ceramide-1-phosphate transfer protein
CRYBB2P1 crystallin, beta B2 pseudogene 1
CUEDC1 CUE domain containing 1
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
EFCAB2 EF-hand calcium binding domain 2
EFNA3 ephrin-A3
EGLN3 egl-9 family hypoxia-inducible factor 3
EGR3 early growth response 3
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
FAAH fatty acid amide hydrolase
FASTKD5 FAST kinase domains 5
FBXO5 F-box protein 5
FGGY FGGY carbohydrate kinase domain containing
FOXC1 forkhead box C1
GMIP GEM interacting protein
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
HDAC4 histone deacetylase 4
HIST1H3G histone cluster 1, H3g
IGFBP4 insulin-like growth factor binding protein 4
IPO13 importin 13
IRF6 interferon regulatory factor 6
KCTD15 potassium channel tetramerization domain containing 15
KIAA0125 KIAA0125
LAMB2 laminin, beta 2 (laminin S)
LIG3 ligase III, DNA, ATP-dependent
LYPLA2P1 lysophospholipase II pseudogene 1
MEIS1 Meis homeobox 1
MT1H metallothionein 1H
NECAB3 N-terminal EF-hand calcium binding protein 3
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)
NRGN neurogranin (protein kinase C substrate, RC3)
NT5E 5'-nucleotidase, ecto (CD73)
OLFML3 olfactomedin-like 3
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PARD6A par-6 family cell polarity regulator alpha
PEX11A peroxisomal biogenesis factor 11 alpha
PEX26 peroxisomal biogenesis factor 26
PMP22 peripheral myelin protein 22
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PRKCD protein kinase C, delta
PSKH1 protein serine kinase H1
RBL1 retinoblastoma-like 1
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RGS19 regulator of G-protein signaling 19
RHOF ras homolog family member F (in filopodia)
RNF121 ring finger protein 121
RPH3AL rabphilin 3A-like (without C2 domains)
RRAGB Ras-related GTP binding B
SCAMP5 secretory carrier membrane protein 5
SH2B3 SH2B adaptor protein 3
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC38A6 solute carrier family 38, member 6
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SNUPN snurportin 1
SOX9 SRY (sex determining region Y)-box 9
STARD13 StAR-related lipid transfer (START) domain containing 13
THOP1 thimet oligopeptidase 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM254 transmembrane protein 254
TMEM51 transmembrane protein 51
TRAPPC11 trafficking protein particle complex 11
TRIM5 tripartite motif containing 5
TRIM66 tripartite motif containing 66
TRIP10 thyroid hormone receptor interactor 10
TRMT61A tRNA methyltransferase 61A
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSKU tsukushi, small leucine rich proteoglycan
TUBA3D tubulin, alpha 3d
TWF2 twinfilin actin binding protein 2
USP18 ubiquitin specific peptidase 18
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
ZC3H3 zinc finger CCCH-type containing 3
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF573 zinc finger protein 573
ZNF586 zinc finger protein 586
ZNF74 zinc finger protein 74
ZNF787 zinc finger protein 787