oxaprozin-4352 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the oxaprozin-4352 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ADAM22 ADAM metallopeptidase domain 22
ADGRB3 adhesion G protein-coupled receptor B3
AJAP1 adherens junctions associated protein 1
ALOXE3 arachidonate lipoxygenase 3
AMN amnion associated transmembrane protein
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BIN1 bridging integrator 1
C10ORF95 chromosome 10 open reading frame 95
C17ORF53 chromosome 17 open reading frame 53
CA9 carbonic anhydrase IX
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CCL21 chemokine (C-C motif) ligand 21
CDHR2 cadherin-related family member 2
CDK18 cyclin-dependent kinase 18
CEP112 centrosomal protein 112kDa
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
CORO2B coronin, actin binding protein, 2B
CRMP1 collapsin response mediator protein 1
CTIF CBP80/20-dependent translation initiation factor
DCHS2 dachsous cadherin-related 2
DMWD dystrophia myotonica, WD repeat containing
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
EDN3 endothelin 3
FBXL7 F-box and leucine-rich repeat protein 7
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGF2 fibroblast growth factor 2 (basic)
FHL1 four and a half LIM domains 1
FRMD1 FERM domain containing 1
GDF5 growth differentiation factor 5
GPR183 G protein-coupled receptor 183
GRM7 glutamate receptor, metabotropic 7
HHAT hedgehog acyltransferase
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
ICAM5 intercellular adhesion molecule 5, telencephalin
IHH indian hedgehog
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MLANA melan-A
MTA2 metastasis associated 1 family, member 2
MXD4 MAX dimerization protein 4
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NGF nerve growth factor (beta polypeptide)
NOTCH4 notch 4
NOVA2 neuro-oncological ventral antigen 2
NPAT nuclear protein, ataxia-telangiectasia locus
NPR3 natriuretic peptide receptor 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR6A1 nuclear receptor subfamily 6, group A, member 1
OR1E1 olfactory receptor, family 1, subfamily E, member 1
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PCDHB6 protocadherin beta 6
PCSK6 proprotein convertase subtilisin/kexin type 6
PGAP3 post-GPI attachment to proteins 3
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PLK3 polo-like kinase 3
POU5F1P3 POU class 5 homeobox 1 pseudogene 3
PRB4 proline-rich protein BstNI subfamily 4
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PVT1 Pvt1 oncogene (non-protein coding)
RASIP1 Ras interacting protein 1
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RIMS2 regulating synaptic membrane exocytosis 2
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNF39 ring finger protein 39
RUNX1 runt-related transcription factor 1
SBNO1 strawberry notch homolog 1 (Drosophila)
SCN11A sodium channel, voltage gated, type XI alpha subunit
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC17A4 solute carrier family 17, member 4
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SORBS1 sorbin and SH3 domain containing 1
SPTB spectrin, beta, erythrocytic
SSX3 synovial sarcoma, X breakpoint 3
STAC SH3 and cysteine rich domain
STS steroid sulfatase (microsomal), isozyme S
SULT4A1 sulfotransferase family 4A, member 1
TAPBPL TAP binding protein-like
TCF25 transcription factor 25 (basic helix-loop-helix)
THSD4 thrombospondin, type I, domain containing 4
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TRIM36 tripartite motif containing 36
TSC2 tuberous sclerosis 2
TSSK2 testis-specific serine kinase 2
VTCN1 V-set domain containing T cell activation inhibitor 1
WDFY3 WD repeat and FYVE domain containing 3
WNT6 wingless-type MMTV integration site family, member 6
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ALOX15 arachidonate 15-lipoxygenase
APOLD1 apolipoprotein L domain containing 1
ARMC4 armadillo repeat containing 4
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATAD5 ATPase family, AAA domain containing 5
ATP10D ATPase, class V, type 10D
BEX4 brain expressed, X-linked 4
BLNK B-cell linker
BRAF B-Raf proto-oncogene, serine/threonine kinase
C14ORF79 chromosome 14 open reading frame 79
C5 complement component 5
C7ORF43 chromosome 7 open reading frame 43
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CASC1 cancer susceptibility candidate 1
CENPO centromere protein O
CIDEB cell death-inducing DFFA-like effector b
CORO7 coronin 7
CSTA cystatin A (stefin A)
CTAGE9 CTAGE family, member 9
CXXC4 CXXC finger protein 4
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DMTN dematin actin binding protein
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNASE1L2 deoxyribonuclease I-like 2
DSCAM Down syndrome cell adhesion molecule
ELSPBP1 epididymal sperm binding protein 1
EPHX2 epoxide hydrolase 2, cytoplasmic
ERO1L ERO1-like (S. cerevisiae)
EXOC6B exocyst complex component 6B
FAM188A family with sequence similarity 188, member A
FAM46C family with sequence similarity 46, member C
FGL1 fibrinogen-like 1
GFI1 growth factor independent 1 transcription repressor
GMEB1 glucocorticoid modulatory element binding protein 1
GPR157 G protein-coupled receptor 157
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUSBP3 glucuronidase, beta pseudogene 3
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
IFT81 intraflagellar transport 81
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KLF11 Kruppel-like factor 11
LIN7A lin-7 homolog A (C. elegans)
LOC157562 uncharacterized LOC157562
LOC257152 uncharacterized LOC257152
LYRM9 LYR motif containing 9
MED31 mediator complex subunit 31
NEK11 NIMA-related kinase 11
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPFFR1 neuropeptide FF receptor 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NT5DC3 5'-nucleotidase domain containing 3
PADI3 peptidyl arginine deiminase, type III
PARP3 poly (ADP-ribose) polymerase family, member 3
PCDH17 protocadherin 17
PDZRN3 PDZ domain containing ring finger 3
PER3 period circadian clock 3
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAB30 RAB30, member RAS oncogene family
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF208 ring finger protein 208
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
S100A7 S100 calcium binding protein A7
SAYSD1 SAYSVFN motif domain containing 1
SCARA3 scavenger receptor class A, member 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SKI SKI proto-oncogene
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNTA1 syntrophin, alpha 1
SNX15 sorting nexin 15
SOAT2 sterol O-acyltransferase 2
SP1 Sp1 transcription factor
SPAG4 sperm associated antigen 4
STON1 stonin 1
STRN striatin, calmodulin binding protein
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TCP10 t-complex 10
TEFM transcription elongation factor, mitochondrial
TEX40 testis expressed 40
TM4SF5 transmembrane 4 L six family member 5
TMC7 transmembrane channel-like 7
TOR4A torsin family 4, member A
TPSG1 tryptase gamma 1
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIM21 tripartite motif containing 21
TSGA10 testis specific, 10
TTBK2 tau tubulin kinase 2
UCN urocortin
USB1 U6 snRNA biogenesis 1
ZNF204P zinc finger protein 204, pseudogene
ZNF573 zinc finger protein 573
ZNF639 zinc finger protein 639
ZNF675 zinc finger protein 675