oxaprozin-3794 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the oxaprozin-3794 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM28 ADAM metallopeptidase domain 28
ADGRA2 adhesion G protein-coupled receptor A2
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALPP alkaline phosphatase, placental
APAF1 apoptotic peptidase activating factor 1
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ASMT acetylserotonin O-methyltransferase
C11ORF16 chromosome 11 open reading frame 16
C8ORF44 chromosome 8 open reading frame 44
CACNG3 calcium channel, voltage-dependent, gamma subunit 3
CCDC71 coiled-coil domain containing 71
CCND2 cyclin D2
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CTNS cystinosin, lysosomal cystine transporter
CTSS cathepsin S
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DIO2 deiodinase, iodothyronine, type II
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DPF1 D4, zinc and double PHD fingers family 1
DRD2 dopamine receptor D2
EMC3 ER membrane protein complex subunit 3
FAM174B family with sequence similarity 174, member B
FAM76A family with sequence similarity 76, member A
FCAR Fc fragment of IgA receptor
FGF9 fibroblast growth factor 9
FHL3 four and a half LIM domains 3
FLJ11292
GLRA1 glycine receptor, alpha 1
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPM6B glycoprotein M6B
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRM8 glutamate receptor, metabotropic 8
GSTTP1 glutathione S-transferase theta pseudogene 1
HAO2 hydroxyacid oxidase 2 (long chain)
HDAC6 histone deacetylase 6
HKDC1 hexokinase domain containing 1
HSPB6 heat shock protein, alpha-crystallin-related, B6
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
KLHL23 kelch-like family member 23
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LAT2 linker for activation of T cells family, member 2
LEF1 lymphoid enhancer-binding factor 1
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LRRN2 leucine rich repeat neuronal 2
LRRN3 leucine rich repeat neuronal 3
LYZL6 lysozyme-like 6
MAGEB4 melanoma antigen family B4
MBD2 methyl-CpG binding domain protein 2
MC5R melanocortin 5 receptor
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MUC3B mucin 3B, cell surface associated
MUC8 mucin 8
MX1 MX dynamin-like GTPase 1
MX2 MX dynamin-like GTPase 2
MYBPC3 myosin binding protein C, cardiac
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
NDN necdin, melanoma antigen (MAGE) family member
NOD2 nucleotide-binding oligomerization domain containing 2
NPHP1 nephronophthisis 1 (juvenile)
NPR1 natriuretic peptide receptor 1
NPY neuropeptide Y
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OR52A1 olfactory receptor, family 52, subfamily A, member 1
PARD6B par-6 family cell polarity regulator beta
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PLCL2 phospholipase C-like 2
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAB30 RAB30, member RAS oncogene family
REG1P regenerating islet-derived 1 pseudogene
RLN2 relaxin 2
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RPA4 replication protein A4, 30kDa
SCARF1 scavenger receptor class F, member 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
SH3GL3 SH3-domain GRB2-like 3
SHOX2 short stature homeobox 2
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SMG7 SMG7 nonsense mediated mRNA decay factor
SPHK2 sphingosine kinase 2
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
THY1 Thy-1 cell surface antigen
TTYH1 tweety family member 1
USP46 ubiquitin specific peptidase 46
VAMP5 vesicle-associated membrane protein 5
WNT3 wingless-type MMTV integration site family, member 3
ZNF280B zinc finger protein 280B

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAP2 ArfGAP with dual PH domains 2
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
AMDHD2 amidohydrolase domain containing 2
ANXA2P1 annexin A2 pseudogene 1
AOC2 amine oxidase, copper containing 2 (retina-specific)
ARPIN actin-related protein 2/3 complex inhibitor
ASPHD1 aspartate beta-hydroxylase domain containing 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATG10 autophagy related 10
C14ORF93 chromosome 14 open reading frame 93
C5ORF42 chromosome 5 open reading frame 42
CBS cystathionine-beta-synthase
CCDC85C coiled-coil domain containing 85C
CCNK cyclin K
CD70 CD70 molecule
CD82 CD82 molecule
CLDN11 claudin 11
CLSTN3 calsyntenin 3
COPZ2 coatomer protein complex, subunit zeta 2
CORT cortistatin
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRMP1 collapsin response mediator protein 1
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DTX2 deltex 2, E3 ubiquitin ligase
DUSP2 dual specificity phosphatase 2
DUSP9 dual specificity phosphatase 9
EGLN3 egl-9 family hypoxia-inducible factor 3
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EREG epiregulin
FBXO31 F-box protein 31
FKBP1B FK506 binding protein 1B, 12.6 kDa
FKBP5 FK506 binding protein 5
FRS3 fibroblast growth factor receptor substrate 3
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HHAT hedgehog acyltransferase
IDI2-AS1 IDI2 antisense RNA 1
IL22 interleukin 22
IPO8 importin 8
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITPKA inositol-trisphosphate 3-kinase A
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KCTD15 potassium channel tetramerization domain containing 15
KIAA0319L KIAA0319-like
KIFC3 kinesin family member C3
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF13 Kruppel-like factor 13
KRT4 keratin 4, type II
LATS1 large tumor suppressor kinase 1
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC257152 uncharacterized LOC257152
LPPR1 lipid phosphate phosphatase-related protein type 1
LRP5L low density lipoprotein receptor-related protein 5-like
MAGEA5 melanoma antigen family A5
MAP2 microtubule-associated protein 2
MB myoglobin
MCC mutated in colorectal cancers
MCOLN3 mucolipin 3
NME5 NME/NM23 family member 5
NPIPB15 nuclear pore complex interacting protein family, member B15
NTNG1 netrin G1
OLFML2B olfactomedin-like 2B
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
PARP3 poly (ADP-ribose) polymerase family, member 3
PHC1 polyhomeotic homolog 1 (Drosophila)
POMT2 protein-O-mannosyltransferase 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRB3 proline-rich protein BstNI subfamily 3
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RNF43 ring finger protein 43
SCIN scinderin
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SLAMF7 SLAM family member 7
SLC12A8 solute carrier family 12, member 8
SLC16A6 solute carrier family 16, member 6
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SLMO1 slowmo homolog 1 (Drosophila)
SPTBN2 spectrin, beta, non-erythrocytic 2
STXBP5L syntaxin binding protein 5-like
TCEAL2 transcription elongation factor A (SII)-like 2
TFCP2L1 transcription factor CP2-like 1
TMEM206 transmembrane protein 206
TRAIP TRAF interacting protein
TSC22D4 TSC22 domain family, member 4
TSKU tsukushi, small leucine rich proteoglycan
TSNAXIP1 translin-associated factor X interacting protein 1
USP20 ubiquitin specific peptidase 20
VGF VGF nerve growth factor inducible
ZBTB33 zinc finger and BTB domain containing 33
ZBTB48 zinc finger and BTB domain containing 48
ZNF428 zinc finger protein 428
ZNF442 zinc finger protein 442
ZNF446 zinc finger protein 446
ZNF702P zinc finger protein 702, pseudogene
ZNF749 zinc finger protein 749