oxamniquine-7344 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the oxamniquine-7344 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCY1 adenylate cyclase 1 (brain)
ADM adrenomedullin
ANGEL2 angel homolog 2 (Drosophila)
ATP9A ATPase, class II, type 9A
C14ORF79 chromosome 14 open reading frame 79
C17ORF70 chromosome 17 open reading frame 70
C1QTNF3 C1q and tumor necrosis factor related protein 3
CDK13 cyclin-dependent kinase 13
CLTA clathrin, light chain A
COX4I1 cytochrome c oxidase subunit IV isoform 1
CRTC1 CREB regulated transcription coactivator 1
CYR61 cysteine-rich, angiogenic inducer, 61
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DIXDC1 DIX domain containing 1
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DSCAM Down syndrome cell adhesion molecule
EGFR epidermal growth factor receptor
EHBP1L1 EH domain binding protein 1-like 1
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM120C family with sequence similarity 120C
FANCC Fanconi anemia, complementation group C
FGL1 fibrinogen-like 1
FMOD fibromodulin
GNG3 guanine nucleotide binding protein (G protein), gamma 3
HCRP1 hepatocellular carcinoma-related HCRP1
HIST1H2AK histone cluster 1, H2ak
HNMT histamine N-methyltransferase
HPX hemopexin
JAM3 junctional adhesion molecule 3
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KLF5 Kruppel-like factor 5 (intestinal)
KLHL24 kelch-like family member 24
KRT13 keratin 13, type I
LHX6 LIM homeobox 6
LMF2 lipase maturation factor 2
LOC157562 uncharacterized LOC157562
LPPR2 lipid phosphate phosphatase-related protein type 2
LY6D lymphocyte antigen 6 complex, locus D
MACF1 microtubule-actin crosslinking factor 1
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MFGE8 milk fat globule-EGF factor 8 protein
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MIIP migration and invasion inhibitory protein
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MYOF myoferlin
NCAPH2 non-SMC condensin II complex, subunit H2
NCOA2 nuclear receptor coactivator 2
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PADI1 peptidyl arginine deiminase, type I
PAOX polyamine oxidase (exo-N4-amino)
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PITX2 paired-like homeodomain 2
PLA2G3 phospholipase A2, group III
PLIN2 perilipin 2
PLK4 polo-like kinase 4
POFUT1 protein O-fucosyltransferase 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
RABGAP1 RAB GTPase activating protein 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RANBP1 RAN binding protein 1
RASAL2 RAS protein activator like 2
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RHOBTB2 Rho-related BTB domain containing 2
RLN1 relaxin 1
RND1 Rho family GTPase 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RRBP1 ribosome binding protein 1
S100A11 S100 calcium binding protein A11
S100A4 S100 calcium binding protein A4
SEC24D SEC24 family member D
SGPL1 sphingosine-1-phosphate lyase 1
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC44A1 solute carrier family 44 (choline transporter), member 1
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SSPN sarcospan
ST20 suppressor of tumorigenicity 20
STK17A serine/threonine kinase 17a
STK17B serine/threonine kinase 17b
SUGP1 SURP and G patch domain containing 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
THSD4 thrombospondin, type I, domain containing 4
TROVE2 TROVE domain family, member 2
TSPAN9 tetraspanin 9
UBXN6 UBX domain protein 6
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VN1R1 vomeronasal 1 receptor 1
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
VPS9D1 VPS9 domain containing 1
VWA1 von Willebrand factor A domain containing 1
WDR61 WD repeat domain 61
ZFHX2 zinc finger homeobox 2
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADCY7 adenylate cyclase 7
AES amino-terminal enhancer of split
ALPK1 alpha-kinase 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANXA2P3 annexin A2 pseudogene 3
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARSB arylsulfatase B
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
C14ORF132 chromosome 14 open reading frame 132
C7ORF43 chromosome 7 open reading frame 43
CBX7 chromobox homolog 7
CCDC88C coiled-coil domain containing 88C
CDK20 cyclin-dependent kinase 20
CHML choroideremia-like (Rab escort protein 2)
CORT cortistatin
CRYZL1 crystallin, zeta (quinone reductase)-like 1
CUL9 cullin 9
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDIT3 DNA-damage-inducible transcript 3
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAL4 dynein, axonemal, light chain 4
DYSF dysferlin
FAM114A1 family with sequence similarity 114, member A1
FAM53B family with sequence similarity 53, member B
FBXL15 F-box and leucine-rich repeat protein 15
FBXO31 F-box protein 31
FOXJ2 forkhead box J2
GLB1L2 galactosidase, beta 1-like 2
GNL1 guanine nucleotide binding protein-like 1
GPR27 G protein-coupled receptor 27
GSTT1 glutathione S-transferase theta 1
HIST1H2AI histone cluster 1, H2ai
HIST1H2BC histone cluster 1, H2bc
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXC10 homeobox C10
HP1BP3 heterochromatin protein 1, binding protein 3
HYI hydroxypyruvate isomerase (putative)
IFI6 interferon, alpha-inducible protein 6
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF9 interferon regulatory factor 9
KAT2A K(lysine) acetyltransferase 2A
KDM5C lysine (K)-specific demethylase 5C
KIF13B kinesin family member 13B
KLHL28 kelch-like family member 28
KREMEN2 kringle containing transmembrane protein 2
KRI1 KRI1 homolog (S. cerevisiae)
KRT24 keratin 24, type I
LIG4 ligase IV, DNA, ATP-dependent
LINC00339 long intergenic non-protein coding RNA 339
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LY6G5C lymphocyte antigen 6 complex, locus G5C
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MED9 mediator complex subunit 9
MFSD11 major facilitator superfamily domain containing 11
MTERF4 mitochondrial transcription termination factor 4
NDE1 nudE neurodevelopment protein 1
NT5DC3 5'-nucleotidase domain containing 3
OFD1 oral-facial-digital syndrome 1
OSGEP O-sialoglycoprotein endopeptidase
PCDHA9 protocadherin alpha 9
PCDHB8 protocadherin beta 8
PODXL podocalyxin-like
QTRT1 queuine tRNA-ribosyltransferase 1
RNF31 ring finger protein 31
RPAIN RPA interacting protein
RPGR retinitis pigmentosa GTPase regulator
SCN1B sodium channel, voltage gated, type I beta subunit
SDC3 syndecan 3
SLC12A8 solute carrier family 12, member 8
SLC41A3 solute carrier family 41, member 3
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SOX12 SRY (sex determining region Y)-box 12
SRD5A3 steroid 5 alpha-reductase 3
SREK1IP1 SREK1-interacting protein 1
STARD3 StAR-related lipid transfer (START) domain containing 3
STARD5 StAR-related lipid transfer (START) domain containing 5
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TCTN1 tectonic family member 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TM7SF3 transmembrane 7 superfamily member 3
TMCC2 transmembrane and coiled-coil domain family 2
TMEM120B transmembrane protein 120B
TMEM180 transmembrane protein 180
TMPRSS3 transmembrane protease, serine 3
TUBA3C tubulin, alpha 3c
VASP vasodilator-stimulated phosphoprotein
VEGFC vascular endothelial growth factor C
WDR62 WD repeat domain 62
WWC2 WW and C2 domain containing 2
ZDHHC13 zinc finger, DHHC-type containing 13
ZNF506 zinc finger protein 506
ZNF623 zinc finger protein 623
ZNF701 zinc finger protein 701