oxamniquine-4124 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the oxamniquine-4124 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACTC1 actin, alpha, cardiac muscle 1
ADAM29 ADAM metallopeptidase domain 29
AHNAK2 AHNAK nucleoprotein 2
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGAP26 Rho GTPase activating protein 26
ARHGAP4 Rho GTPase activating protein 4
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ATF7IP activating transcription factor 7 interacting protein
ATXN2L ataxin 2-like
B9D1 B9 protein domain 1
C11ORF16 chromosome 11 open reading frame 16
C1ORF95 chromosome 1 open reading frame 95
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CCKAR cholecystokinin A receptor
CCL27 chemokine (C-C motif) ligand 27
COL6A1 collagen, type VI, alpha 1
CRTAC1 cartilage acidic protein 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DCT dopachrome tautomerase
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DFNB31 deafness, autosomal recessive 31
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DMPK dystrophia myotonica-protein kinase
DMTN dematin actin binding protein
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
ELL2 elongation factor, RNA polymerase II, 2
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
FADS2 fatty acid desaturase 2
FAM182B family with sequence similarity 182, member B
FKRP fukutin related protein
FSCN3 fascin actin-bundling protein 3, testicular
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GFI1 growth factor independent 1 transcription repressor
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GUSBP3 glucuronidase, beta pseudogene 3
HIF3A hypoxia inducible factor 3, alpha subunit
HLA-C major histocompatibility complex, class I, C
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INE1 inactivation escape 1 (non-protein coding)
IPW imprinted in Prader-Willi syndrome (non-protein coding)
JAM3 junctional adhesion molecule 3
KHSRP KH-type splicing regulatory protein
KIAA1107 KIAA1107
LIME1 Lck interacting transmembrane adaptor 1
LRRC37A3 leucine rich repeat containing 37, member A3
MAP1A microtubule-associated protein 1A
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MR1 major histocompatibility complex, class I-related
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYCNOS MYCN opposite strand
MYT1 myelin transcription factor 1
NCKIPSD NCK interacting protein with SH3 domain
NCOR2 nuclear receptor corepressor 2
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NRN1 neuritin 1
NTN1 netrin 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OR1G1 olfactory receptor, family 1, subfamily G, member 1
ORM1 orosomucoid 1
PILRA paired immunoglobin-like type 2 receptor alpha
PKD2L2 polycystic kidney disease 2-like 2
PLAC4 placenta-specific 4
PLLP plasmolipin
PTGDR2 prostaglandin D2 receptor 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RERE arginine-glutamic acid dipeptide (RE) repeats
RGCC regulator of cell cycle
RORC RAR-related orphan receptor C
RPL35A ribosomal protein L35a
RSU1 Ras suppressor protein 1
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SNED1 sushi, nidogen and EGF-like domains 1
SPAG8 sperm associated antigen 8
SPINK1 serine peptidase inhibitor, Kazal type 1
SUGP1 SURP and G patch domain containing 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SVIL supervillin
TBX5 T-box 5
TK2 thymidine kinase 2, mitochondrial
TP53I11 tumor protein p53 inducible protein 11
TUBA3C tubulin, alpha 3c
WDR62 WD repeat domain 62
WNT10B wingless-type MMTV integration site family, member 10B
WSB1 WD repeat and SOCS box containing 1
ZNF592 zinc finger protein 592
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ADAM15 ADAM metallopeptidase domain 15
APLP1 amyloid beta (A4) precursor-like protein 1
BMP15 bone morphogenetic protein 15
C11ORF30 chromosome 11 open reading frame 30
C14ORF79 chromosome 14 open reading frame 79
C2ORF27A chromosome 2 open reading frame 27A
CCDC186 coiled-coil domain containing 186
CDK3 cyclin-dependent kinase 3
CES3 carboxylesterase 3
COPZ2 coatomer protein complex, subunit zeta 2
CORO7 coronin 7
CPA4 carboxypeptidase A4
CTRL chymotrypsin-like
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOK5 docking protein 5
ELP6 elongator acetyltransferase complex subunit 6
EPHX2 epoxide hydrolase 2, cytoplasmic
FBXL7 F-box and leucine-rich repeat protein 7
FBXO31 F-box protein 31
FGD1 FYVE, RhoGEF and PH domain containing 1
FGF13 fibroblast growth factor 13
FRMD1 FERM domain containing 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPATCH2L G patch domain containing 2-like
GPRC5D G protein-coupled receptor, class C, group 5, member D
GRIP2 glutamate receptor interacting protein 2
GRPR gastrin-releasing peptide receptor
HAND1 heart and neural crest derivatives expressed 1
HOXA4 homeobox A4
HOXB2 homeobox B2
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IDI2-AS1 IDI2 antisense RNA 1
IGSF1 immunoglobulin superfamily, member 1
IQSEC2 IQ motif and Sec7 domain 2
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNK10 potassium channel, two pore domain subfamily K, member 10
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLHL25 kelch-like family member 25
LIN7A lin-7 homolog A (C. elegans)
LMAN1 lectin, mannose-binding, 1
LRRC16A leucine rich repeat containing 16A
LRRC20 leucine rich repeat containing 20
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MBTPS2 membrane-bound transcription factor peptidase, site 2
METTL16 methyltransferase like 16
MGC2889 uncharacterized protein MGC2889
MOCS3 molybdenum cofactor synthesis 3
MUC3A mucin 3A, cell surface associated
NOD1 nucleotide-binding oligomerization domain containing 1
PAIP2B poly(A) binding protein interacting protein 2B
PARD6A par-6 family cell polarity regulator alpha
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
POPDC3 popeye domain containing 3
POU4F2 POU class 4 homeobox 2
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RHBDD3 rhomboid domain containing 3
RNF122 ring finger protein 122
RPL23AP32 ribosomal protein L23a pseudogene 32
SAMD9 sterile alpha motif domain containing 9
SCN10A sodium channel, voltage gated, type X alpha subunit
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLN sarcolipin
STAB2 stabilin 2
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBCC tubulin folding cofactor C
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TET3 tet methylcytosine dioxygenase 3
TEX40 testis expressed 40
TMEM209 transmembrane protein 209
TMPRSS3 transmembrane protease, serine 3
TRABD TraB domain containing
TRIM25 tripartite motif containing 25
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSGA10 testis specific, 10
TTC30A tetratricopeptide repeat domain 30A
TYRP1 tyrosinase-related protein 1
UPP1 uridine phosphorylase 1
VAV1 vav 1 guanine nucleotide exchange factor
XDH xanthine dehydrogenase
ZBTB44 zinc finger and BTB domain containing 44
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF205 zinc finger protein 205
ZSCAN31 zinc finger and SCAN domain containing 31