ovary adenocarcinoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An ovarian carcinoma that derives_from epithelial cells of glandular origin. (Human Disease Ontology, DOID_3713)
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Genes

279 genes co-occuring with the disease ovary adenocarcinoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ARID1A AT rich interactive domain 1A (SWI-like) 1.17851
KRT7 keratin 7, type II 1.01723
ASTL astacin-like metallo-endopeptidase (M12 family) 1.01259
TP53 tumor protein p53 1.00119
LACTB2 lactamase, beta 2 0.935385
ZNF217 zinc finger protein 217 0.916787
COL16A1 collagen, type XVI, alpha 1 0.916787
AARSD1 alanyl-tRNA synthetase domain containing 1 0.901567
KRT20 keratin 20, type I 0.847078
KRT72 keratin 72, type II 0.841344
WT1-AS WT1 antisense RNA 0.821667
RBMS1 RNA binding motif, single stranded interacting protein 1 0.821667
ESR1 estrogen receptor 1 0.792951
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.792131
SERPINB11 serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene) 0.789672
VASH2 vasohibin 2 0.768801
NOM1 nucleolar protein with MIF4G domain 1 0.759416
SGPP1 sphingosine-1-phosphate phosphatase 1 0.747204
GSTK1 glutathione S-transferase kappa 1 0.746391
NBPF8 neuroblastoma breakpoint family, member 8 0.729357
CHAD chondroadherin 0.728547
LMX1A LIM homeobox transcription factor 1, alpha 0.72127
FGF16 fibroblast growth factor 16 0.714408
BAX BCL2-associated X protein 0.711587
SHROOM2 shroom family member 2 0.70434
AFP alpha-fetoprotein 0.697109
UBE4A ubiquitination factor E4A 0.691896
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2 0.688291
ZG16B zymogen granule protein 16B 0.686691
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 0.6608
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 0.659611
USP2 ubiquitin specific peptidase 2 0.649323
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.646953
TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2 0.622575
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.617486
SFRP5 secreted frizzled-related protein 5 0.617094
MFAP5 microfibrillar associated protein 5 0.614747
CLDN15 claudin 15 0.613965
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.608885
CDX2 caudal type homeobox 2 0.607714
ZIC4 Zic family member 4 0.59913
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 0.594454
PNPT1 polyribonucleotide nucleotidyltransferase 1 0.583552
FOLR2 folate receptor 2 (fetal) 0.581606
FCGBP Fc fragment of IgG binding protein 0.581217
ANXA4 annexin A4 0.562169
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 0.558285
LRMP lymphoid-restricted membrane protein 0.557897
ESR2 estrogen receptor 2 (ER beta) 0.555568
PLXND1 plexin D1 0.549359
MUC16 mucin 16, cell surface associated 0.548971
MUC21 mucin 21, cell surface associated 0.546644
PAEP progestagen-associated endometrial protein 0.541992
FSHR follicle stimulating hormone receptor 0.541217
NEU4 sialidase 4 0.532701
CBX7 chromobox homolog 7 0.529994
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.521888
RGPD3 RANBP2-like and GRIP domain containing 3 0.516494
CLDN3 claudin 3 0.514186
CXCL14 chemokine (C-X-C motif) ligand 14 0.512264
BRCA1 breast cancer 1, early onset 0.50689
LGALS7 lectin, galactoside-binding, soluble, 7 0.506123
PGR progesterone receptor 0.504207
PTEN phosphatase and tensin homolog 0.496939
MMP2 matrix metallopeptidase 2 0.495411
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 0.494648
SLC45A3 solute carrier family 45, member 3 0.494648
CD44 CD44 molecule (Indian blood group) 0.483604
ERBB2 erb-b2 receptor tyrosine kinase 2 0.480945
KRAS Kirsten rat sarcoma viral oncogene homolog 0.480566
FOLR1 folate receptor 1 (adult) 0.480186
HNF1B HNF1 homeobox B 0.478668
CSK c-src tyrosine kinase 0.476772
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.472225
POLE polymerase (DNA directed), epsilon, catalytic subunit 0.450701
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 0.450324
SPON1 spondin 1, extracellular matrix protein 0.447687
ONECUT3 one cut homeobox 3 0.444676
SDC3 syndecan 3 0.444676
PCNA proliferating cell nuclear antigen 0.43941
SAA4 serum amyloid A4, constitutive 0.435275
PZP pregnancy-zone protein 0.427765
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 0.425514
SMAD4 SMAD family member 4 0.42289
GNRH2 gonadotropin-releasing hormone 2 0.42139
GPX3 glutathione peroxidase 3 0.419142
REEP5 receptor accessory protein 5 0.418394
TCF21 transcription factor 21 0.414276
MSH3 mutS homolog 3 0.413901
BIRC5 baculoviral IAP repeat containing 5 0.411283
NBPF10 neuroblastoma breakpoint family, member 10 0.410535
EMP2 epithelial membrane protein 2 0.410535
NR5A1 nuclear receptor subfamily 5, group A, member 1 0.410535
GNRHR gonadotropin-releasing hormone receptor 0.409787
PITX2 paired-like homeodomain 2 0.407919
ICK intestinal cell (MAK-like) kinase 0.407919
EPHB1 EPH receptor B1 0.405678
NEU3 sialidase 3 (membrane sialidase) 0.405678
FN1 fibronectin 1 0.403064
ALPP alkaline phosphatase, placental 0.400453
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.40008
SART1 squamous cell carcinoma antigen recognized by T cells 0.394491
AHRR aryl-hydrocarbon receptor repressor 0.391513
ZEB2 zinc finger E-box binding homeobox 2 0.390397
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like 0.389281
AMY1A amylase, alpha 1A (salivary) 0.387794
AMY1B amylase, alpha 1B (salivary) 0.387794
AMY1C amylase, alpha 1C (salivary) 0.387794
TRPC4 transient receptor potential cation channel, subfamily C, member 4 0.385936
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.382966
VASH1 vasohibin 1 0.382966
LGALS7B lectin, galactoside-binding, soluble, 7B 0.382594
ICAM3 intercellular adhesion molecule 3 0.382223
SEBOX SEBOX homeobox 0.38111
BCL2 B-cell CLL/lymphoma 2 0.380739
CDKN2A cyclin-dependent kinase inhibitor 2A 0.374068
RANBP2 RAN binding protein 2 0.372958
PRSS8 protease, serine, 8 0.371847
HRAS Harvey rat sarcoma viral oncogene homolog 0.369997
WT1 Wilms tumor 1 0.368518
IRF9 interferon regulatory factor 9 0.367779
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.36704
ALPPL2 alkaline phosphatase, placental-like 2 0.351187
ALPL alkaline phosphatase, liver/bone/kidney 0.350452
BID BH3 interacting domain death agonist 0.345675
BCAM basal cell adhesion molecule (Lutheran blood group) 0.341272
TOP1 topoisomerase (DNA) I 0.339073
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.334681
NEU2 sialidase 2 (cytosolic sialidase) 0.333583
IL6ST interleukin 6 signal transducer 0.328834
PEG3 paternally expressed 3 0.328105
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.324823
ETV5 ets variant 5 0.323002
BCL2L1 BCL2-like 1 0.322273
SMAD3 SMAD family member 3 0.321545
PTHLH parathyroid hormone-like hormone 0.320454
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.319726
CALB2 calbindin 2 0.318999
LTBP3 latent transforming growth factor beta binding protein 3 0.316819
GAST gastrin 0.316092
FST follistatin 0.315729
C10ORF2 chromosome 10 open reading frame 2 0.31464
HTRA3 HtrA serine peptidase 3 0.309566
IFI30 interferon, gamma-inducible protein 30 0.307757
CAND2 cullin-associated and neddylation-dissociated 2 (putative) 0.303781
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.303059
GPC1 glypican 1 0.302337
CLDN7 claudin 7 0.300894
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene) 0.295492
VEGFA vascular endothelial growth factor A 0.289027
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.288668
CRABP1 cellular retinoic acid binding protein 1 0.285444
LTBP2 latent transforming growth factor beta binding protein 2 0.28151
MSLN mesothelin 0.277227
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.267977
MCAM melanoma cell adhesion molecule 0.266558
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.265494
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.255241
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.254536
CSH2 chorionic somatomammotropin hormone 2 0.246799
SP3 Sp3 transcription factor 0.244696
MSH6 mutS homolog 6 0.242245
KLK10 kallikrein-related peptidase 10 0.241196
ACTA2 actin, alpha 2, smooth muscle, aorta 0.238403
GPC3 glypican 3 0.238054
UPK3A uroplakin 3A 0.235616
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.235268
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.233183
TGFB1 transforming growth factor, beta 1 0.232142
MSH2 mutS homolog 2 0.229024
KRT4 keratin 4, type II 0.227642
EGFR epidermal growth factor receptor 0.226607
LONP1 lon peptidase 1, mitochondrial 0.226262
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.224196
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.223165
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.221793
IGFBP7 insulin-like growth factor binding protein 7 0.220766
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.218374
BRCA2 breast cancer 2, early onset 0.215314
BAD BCL2-associated agonist of cell death 0.211934
LIFR leukemia inhibitory factor receptor alpha 0.207245
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.203275
HHAT hedgehog acyltransferase 0.200656
RAB8A RAB8A, member RAS oncogene family 0.198386
MYEF2 myelin expression factor 2 0.195183
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 0.193915
KRT18 keratin 18, type I 0.193285
THBS2 thrombospondin 2 0.192031
PDGFA platelet-derived growth factor alpha polypeptide 0.192031
MRI1 methylthioribose-1-phosphate isomerase 1 0.190786
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.189551
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.189551
AR androgen receptor 0.189551
SNAI1 snail family zinc finger 1 0.188326
MET MET proto-oncogene, receptor tyrosine kinase 0.188326
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.18621
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.183835
HOXA10 homeobox A10 0.183835
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.183541
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.182957
ZAK sterile alpha motif and leucine zipper containing kinase AZK 0.182666
TRPC1 transient receptor potential cation channel, subfamily C, member 1 0.180937
TFPI2 tissue factor pathway inhibitor 2 0.170544
ASPH aspartate beta-hydroxylase 0.166319
CLDN4 claudin 4 0.165001
PROM1 prominin 1 0.163938
NME1 NME/NM23 nucleoside diphosphate kinase 1 0.163111
H2AFX H2A histone family, member X 0.162707
JMJD6 jumonji domain containing 6 0.162306
INSL3 insulin-like 3 (Leydig cell) 0.160761
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.159838
IFNAR2 interferon (alpha, beta and omega) receptor 2 0.159658
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.15948
PLAU plasminogen activator, urokinase 0.158951
HTRA2 HtrA serine peptidase 2 0.14535
JUP junction plakoglobin 0.145285
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 0.144667
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.144358
MAPK1 mitogen-activated protein kinase 1 0.144333
TAGLN transgelin 0.144278
COL4A5 collagen, type IV, alpha 5 0.144133
HTRA1 HtrA serine peptidase 1 0.143926
NANOG Nanog homeobox 0.142461
MGP matrix Gla protein 0.134954
VIL1 villin 1 0.134269
MN1 meningioma (disrupted in balanced translocation) 1 0.134076
FTL ferritin, light polypeptide 0.134025
FTH1 ferritin, heavy polypeptide 1 0.134016
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.133588
THY1 Thy-1 cell surface antigen 0.131011
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.130988
KLKB1 kallikrein B, plasma (Fletcher factor) 1 0.130304
AMACR alpha-methylacyl-CoA racemase 0.129823
AURKA aurora kinase A 0.129323
SACS sacsin molecular chaperone 0.128268
ST14 suppression of tumorigenicity 14 (colon carcinoma) 0.127972
NFIA nuclear factor I/A 0.127806
NFIB nuclear factor I/B 0.127263
ALPI alkaline phosphatase, intestinal 0.127185
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 0.125866
CDH13 cadherin 13 0.125671
PALB2 partner and localizer of BRCA2 0.125439
KRT10 keratin 10, type I 0.125404
SMAD2 SMAD family member 2 0.12535
IGFBP3 insulin-like growth factor binding protein 3 0.12535
GSS glutathione synthetase 0.124417
ZEB1 zinc finger E-box binding homeobox 1 0.124417
GSTM2 glutathione S-transferase mu 2 (muscle) 0.123712
MUC2 mucin 2, oligomeric mucus/gel-forming 0.122268
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 0.121986
NKX2-1 NK2 homeobox 1 0.121874
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 0.121829
STS steroid sulfatase (microsomal), isozyme S 0.121761
SFRP1 secreted frizzled-related protein 1 0.120539
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.120466
RPS6 ribosomal protein S6 0.120418
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1 0.119364
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.117388
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.117306
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.117279
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.115448
THBD thrombomodulin 0.114325
RUNX1 runt-related transcription factor 1 0.114263
TERT telomerase reverse transcriptase 0.113702
GKN2 gastrokine 2 0.113383
LYZ lysozyme 0.113191
MAP4 microtubule-associated protein 4 0.112936
MUC1 mucin 1, cell surface associated 0.10973
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.109084
MNX1 motor neuron and pancreas homeobox 1 0.108345
IVL involucrin 0.107746
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.105616
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.105536
GSTP1 glutathione S-transferase pi 1 0.102702
IGFBP1 insulin-like growth factor binding protein 1 0.101931
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.101845
SPP1 secreted phosphoprotein 1 0.096791
ACPP acid phosphatase, prostate 0.09541
PDPN podoplanin 0.095266