ovarian cancer Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A female reproductive organ cancer that is located_in the ovary. (Human Disease Ontology, DOID_2394)
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Genes

429 genes associated with the disease ovarian cancer in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADAM8 ADAM metallopeptidase domain 8
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2
AKTIP AKT interacting protein
ANKLE1 ankyrin repeat and LEM domain containing 1
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
AR androgen receptor
AREG amphiregulin
ARL11 ADP-ribosylation factor-like 11
ATF1 activating transcription factor 1
ATM ATM serine/threonine kinase
AURKA aurora kinase A
AXIN2 axin 2
BABAM1 BRISC and BRCA1 A complex member 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BARD1 BRCA1 associated RING domain 1
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BIRC5 baculoviral IAP repeat containing 5
BMP1 bone morphogenetic protein 1
BMP4 bone morphogenetic protein 4
BNC2 basonuclin 2
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BST2 bone marrow stromal cell antigen 2
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C3 complement component 3
CALCA calcitonin-related polypeptide alpha
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCL11 chemokine (C-C motif) ligand 11
CCL13 chemokine (C-C motif) ligand 13
CCL7 chemokine (C-C motif) ligand 7
CCNA1 cyclin A1
CCNA2 cyclin A2
CCNB1 cyclin B1
CCNB2 cyclin B2
CCND1 cyclin D1
CCND2 cyclin D2
CCND3 cyclin D3
CCNE1 cyclin E1
CCNE2 cyclin E2
CCNG1 cyclin G1
CCNG2 cyclin G2
CD24 CD24 molecule
CD44 CD44 molecule (Indian blood group)
CD70 CD70 molecule
CDC20 cell division cycle 20
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDK6 cyclin-dependent kinase 6
CDK7 cyclin-dependent kinase 7
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CFLAR CASP8 and FADD-like apoptosis regulator
CHD5 chromodomain helicase DNA binding protein 5
CHEK2 checkpoint kinase 2
CNTLN centlein, centrosomal protein
COMT catechol-O-methyltransferase
COX1
COX2
COX3
CPB2 carboxypeptidase B2 (plasma)
CRLF3 cytokine receptor-like factor 3
CSF1 colony stimulating factor 1 (macrophage)
CTGF connective tissue growth factor
CTSD cathepsin D
CTSK cathepsin K
CUL1 cullin 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR6 chemokine (C-X-C motif) receptor 6
CYC1 cytochrome c-1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYR61 cysteine-rich, angiogenic inducer, 61
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DCN decorin
DDR2 discoidin domain receptor tyrosine kinase 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPP4 dipeptidyl-peptidase 4
DPYD dihydropyrimidine dehydrogenase
DUSP5 dual specificity phosphatase 5
E2F1 E2F transcription factor 1
E2F2 E2F transcription factor 2
E2F3 E2F transcription factor 3
E2F4 E2F transcription factor 4, p107/p130-binding
E2F5 E2F transcription factor 5, p130-binding
E2F6 E2F transcription factor 6
ECHDC1 ethylmalonyl-CoA decarboxylase 1
EGF epidermal growth factor
EGR2 early growth response 2
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EPCAM epithelial cell adhesion molecule
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERCC5 excision repair cross-complementation group 5
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
EZR ezrin
FAM84B family with sequence similarity 84, member B
FGF2 fibroblast growth factor 2 (basic)
FGFR2 fibroblast growth factor receptor 2
FILIP1L filamin A interacting protein 1-like
FLT3LG fms-related tyrosine kinase 3 ligand
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FSHR follicle stimulating hormone receptor
FST follistatin
GABARAPL1 GABA(A) receptor-associated protein like 1
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GALT galactose-1-phosphate uridylyltransferase
GAS1 growth arrest-specific 1
GATA6 GATA binding protein 6
GJB1 gap junction protein, beta 1, 32kDa
GJB2 gap junction protein, beta 2, 26kDa
GPX4 glutathione peroxidase 4
GSTA1 glutathione S-transferase alpha 1
GSTM1 glutathione S-transferase mu 1
GSTM3 glutathione S-transferase mu 3 (brain)
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
H1F0 H1 histone family, member 0
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HOXB2 homeobox B2
HOXD1 homeobox D1
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFI16 interferon, gamma-inducible protein 16
IFI35 interferon-induced protein 35
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGFBP1 insulin-like growth factor binding protein 1
IGFBP3 insulin-like growth factor binding protein 3
IGFBP4 insulin-like growth factor binding protein 4
IGFBP5 insulin-like growth factor binding protein 5
IGFBP6 insulin-like growth factor binding protein 6
IL10 interleukin 10
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL23R interleukin 23 receptor
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
INHBA inhibin, beta A
INS insulin
IRF7 interferon regulatory factor 7
ISG15 ISG15 ubiquitin-like modifier
ITGA6 integrin, alpha 6
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JUN jun proto-oncogene
KAT2B K(lysine) acetyltransferase 2B
KLF10 Kruppel-like factor 10
KLK10 kallikrein-related peptidase 10
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRAS Kirsten rat sarcoma viral oncogene homolog
L1CAM L1 cell adhesion molecule
LAMC1 laminin, gamma 1 (formerly LAMB2)
LCN2 lipocalin 2
LIG4 ligase IV, DNA, ATP-dependent
LOC648570 uncharacterized LOC648570
MAPK1 mitogen-activated protein kinase 1
MAPT microtubule-associated protein tau
MCM2 minichromosome maintenance complex component 2
MCM6 minichromosome maintenance complex component 6
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MEST mesoderm specific transcript
MFAP4 microfibrillar-associated protein 4
MIR106B microRNA 106b
MIR10B microRNA 10b
MIR125A microRNA 125a
MIR125B1 microRNA 125b-1
MIR125B2 microRNA 125b-2
MIR132 microRNA 132
MIR139 microRNA 139
MIR140 microRNA 140
MIR143 microRNA 143
MIR145 microRNA 145
MIR146A microRNA 146a
MIR149 microRNA 149
MIR154 microRNA 154
MIR17 microRNA 17
MIR185 microRNA 185
MIR188 microRNA 188
MIR191 microRNA 191
MIR197 microRNA 197
MIR198 microRNA 198
MIR19A microRNA 19a
MIR200A microRNA 200a
MIR200C microRNA 200c
MIR205 microRNA 205
MIR206 microRNA 206
MIR20A microRNA 20a
MIR21 microRNA 21
MIR216A microRNA 216a
MIR221 microRNA 221
MIR222 microRNA 222
MIR26B microRNA 26b
MIR27A microRNA 27a
MIR29A microRNA 29a
MIR29B2 microRNA 29b-2
MIR320A microRNA 320a
MIR369 microRNA 369
MIR370 microRNA 370
MIR381 microRNA 381
MIR423 microRNA 423
MIR9-1 microRNA 9-1
MIR9-2 microRNA 9-2
MIR9-3 microRNA 9-3
MIR92A1 microRNA 92a-1
MIR93 microRNA 93
MIRLET7A1 microRNA let-7a-1
MIRLET7A2 microRNA let-7a-2
MIRLET7A3 microRNA let-7a-3
MIRLET7B microRNA let-7b
MKI67 marker of proliferation Ki-67
MLH1 mutL homolog 1
MLH3 mutL homolog 3
MMP1 matrix metallopeptidase 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP26 matrix metallopeptidase 26
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MPI mannose phosphate isomerase
MPO myeloperoxidase
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MSH2 mutS homolog 2
MSH3 mutS homolog 3
MSH6 mutS homolog 6
MT-ATP6 ATP synthase F0 subunit 6
MT-ATP8 ATP synthase F0 subunit 8
MT-ND2 MTND2
MT-TA tRNA
MT-TC tRNA
MT-TD tRNA
MT-TG tRNA
MT-TK tRNA
MT-TR tRNA
MT-TS1 tRNA
MT-TW tRNA
MT-TY tRNA
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MUC1 mucin 1, cell surface associated
MX1 MX dynamin-like GTPase 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NBN nibrin
NCOA3 nuclear receptor coactivator 3
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NMI N-myc (and STAT) interactor
NOD2 nucleotide-binding oligomerization domain containing 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH3 notch 3
NQO1 NAD(P)H dehydrogenase, quinone 1
NT5E 5'-nucleotidase, ecto (CD73)
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OGG1 8-oxoguanine DNA glycosylase
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
OSMR oncostatin M receptor
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PANX1 pannexin 1
PCNA proliferating cell nuclear antigen
PDGFB platelet-derived growth factor beta polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDPN podoplanin
PGR progesterone receptor
PHB prohibitin
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLK1 polo-like kinase 1
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PODXL podocalyxin-like
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
PON1 paraoxonase 1
POU5F1B POU class 5 homeobox 1B
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
PTEN phosphatase and tensin homolog
PTGES prostaglandin E synthase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTTG1 pituitary tumor-transforming 1
RAD50 RAD50 homolog (S. cerevisiae)
RAD51 RAD51 recombinase
RAD51C RAD51 paralog C
RAD52 RAD52 homolog (S. cerevisiae)
RB1 retinoblastoma 1
RBBP8 retinoblastoma binding protein 8
RBL1 retinoblastoma-like 1
RBL2 retinoblastoma-like 2
RGCC regulator of cell cycle
RGS2 regulator of G-protein signaling 2
RNF146 ring finger protein 146
RSAD2 radical S-adenosyl methionine domain containing 2
RUVBL1 RuvB-like AAA ATPase 1
S100A7 S100 calcium binding protein A7
SAT1 spermidine/spermine N1-acetyltransferase 1
SELENBP1 selenium binding protein 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SKAP1 src kinase associated phosphoprotein 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SNAI1 snail family zinc finger 1
SOD2 superoxide dismutase 2, mitochondrial
SORD sorbitol dehydrogenase
SORT1 sortilin 1
SOX9 SRY (sex determining region Y)-box 9
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPP1 secreted phosphoprotein 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3 stromal antigen 3
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STEAP1 six transmembrane epithelial antigen of the prostate 1
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SYNE1 spectrin repeat containing, nuclear envelope 1
TCEAL1 transcription elongation factor A (SII)-like 1
TCEAL7 transcription elongation factor A (SII)-like 7
TERT telomerase reverse transcriptase
TFDP1 transcription factor Dp-1
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
THBS4 thrombospondin 4
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNF tumor necrosis factor
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TOPBP1 topoisomerase (DNA) II binding protein 1
TP53 tumor protein p53
TRIM21 tripartite motif containing 21
TWIST1 twist family bHLH transcription factor 1
TYK2 tyrosine kinase 2
TYMS thymidylate synthetase
TYROBP TYRO protein tyrosine kinase binding protein
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
WISP1 WNT1 inducible signaling pathway protein 1
WNT10B wingless-type MMTV integration site family, member 10B
WNT2 wingless-type MMTV integration site family member 2
WNT5A wingless-type MMTV integration site family, member 5A
WWOX WW domain containing oxidoreductase
XPA xeroderma pigmentosum, complementation group A
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF350 zinc finger protein 350
ZNF354A zinc finger protein 354A