osteogenic cell line Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
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Genes

283 proteins co-occuring with the tissue osteogenic cell line in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
RUNX2 runt-related transcription factor 2 2.57402
ALPL alkaline phosphatase, liver/bone/kidney 2.56619
BGLAP bone gamma-carboxyglutamate (gla) protein 2.56359
ALPPL2 alkaline phosphatase, placental-like 2 2.56163
ALPP alkaline phosphatase, placental 2.55903
BMP2 bone morphogenetic protein 2 2.28159
SP7 Sp7 transcription factor 2.13577
IBSP integrin-binding sialoprotein 2.03321
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 1.97889
SPP1 secreted phosphoprotein 1 1.84864
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.81175
PTH parathyroid hormone 1.79448
MAPK14 mitogen-activated protein kinase 14 1.66107
BMP4 bone morphogenetic protein 4 1.39284
TGFB1 transforming growth factor, beta 1 1.35767
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.34179
JUN jun proto-oncogene 1.3341
PTHLH parathyroid hormone-like hormone 1.28009
IL6 interleukin 6 1.26263
MSX2 msh homeobox 2 1.25547
DLX5 distal-less homeobox 5 1.23717
NPNT nephronectin 1.21446
FGF2 fibroblast growth factor 2 (basic) 1.2109
NOG noggin 1.198
IGF1 insulin-like growth factor 1 (somatomedin C) 1.17358
COL1A1 collagen, type I, alpha 1 1.17314
FN1 fibronectin 1 1.16338
BMP7 bone morphogenetic protein 7 1.15229
BMP3 bone morphogenetic protein 3 1.139
BMP6 bone morphogenetic protein 6 1.1359
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.11686
ACPP acid phosphatase, prostate 1.09695
FOS FBJ murine osteosarcoma viral oncogene homolog 1.09164
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.05897
MMP13 matrix metallopeptidase 13 1.04752
PTH1R parathyroid hormone 1 receptor 1.04269
WNT3A wingless-type MMTV integration site family, member 3A 1.02776
TNF tumor necrosis factor 0.985859
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 0.982386
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.972417
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.972417
TXLNG taxilin gamma 0.971984
MAPK8 mitogen-activated protein kinase 8 0.970253
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.924623
PHEX phosphate regulating endopeptidase homolog, X-linked 0.915215
CTSK cathepsin K 0.907109
SOST sclerostin 0.906682
LOX lysyl oxidase 0.89817
PLAA phospholipase A2-activating protein 0.896045
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.891374
SMAD5 SMAD family member 5 0.888405
GDF2 growth differentiation factor 2 0.883321
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.876552
RNF185 ring finger protein 185 0.861363
ATF4 activating transcription factor 4 0.861363
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.857995
CASR calcium-sensing receptor 0.852106
LRP5 low density lipoprotein receptor-related protein 5 0.845385
HELLS helicase, lymphoid-specific 0.816486
IL1A interleukin 1, alpha 0.812726
MEPE matrix extracellular phosphoglycoprotein 0.788547
PDIA3 protein disulfide isomerase family A, member 3 0.778155
CREB1 cAMP responsive element binding protein 1 0.771514
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 0.771514
OGN osteoglycin 0.767783
ZNF384 zinc finger protein 384 0.74174
IGFBP6 insulin-like growth factor binding protein 6 0.729385
FOSL1 FOS-like antigen 1 0.722809
FGFR2 fibroblast growth factor receptor 2 0.720755
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 0.716241
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.713369
FGF1 fibroblast growth factor 1 (acidic) 0.686368
RGN regucalcin 0.684735
ELF4 E74-like factor 4 (ets domain transcription factor) 0.67495
GJA1 gap junction protein, alpha 1, 43kDa 0.67495
MOSPD1 motile sperm domain containing 1 0.665588
BGN biglycan 0.664775
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 0.656648
COL1A2 collagen, type I, alpha 2 0.648127
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.647316
VCL vinculin 0.63638
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 0.630314
TGM2 transglutaminase 2 0.627081
GGPS1 geranylgeranyl diphosphate synthase 1 0.61941
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 0.6182
UBAP2L ubiquitin associated protein 2-like 0.608124
ESR1 estrogen receptor 1 0.600479
TOB2 transducer of ERBB2, 2 0.600077
NELL1 NEL-like 1 (chicken) 0.595255
MOSPD2 motile sperm domain containing 2 0.59405
MGP matrix Gla protein 0.593649
BMP1 bone morphogenetic protein 1 0.592043
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.579617
POSTN periostin, osteoblast specific factor 0.576415
ALB albumin 0.56603
TRAM2 translocation associated membrane protein 2 0.564833
MRAS muscle RAS oncogene homolog 0.558457
TMEM119 transmembrane protein 119 0.55607
FGF23 fibroblast growth factor 23 0.54812
IL1B interleukin 1, beta 0.538209
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.529508
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 0.529113
NPPC natriuretic peptide C 0.525955
FIGNL1 fidgetin-like 1 0.52556
PRDX5 peroxiredoxin 5 0.521223
GSK3B glycogen synthase kinase 3 beta 0.517284
BMP8B bone morphogenetic protein 8b 0.51453
LNX2 ligand of numb-protein X 2 0.510206
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.502357
SMAD9 SMAD family member 9 0.501574
PDGFB platelet-derived growth factor beta polypeptide 0.50079
EDN1 endothelin 1 0.49844
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 0.496483
CHD9 chromodomain helicase DNA binding protein 9 0.493354
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d 0.492182
SPP2 secreted phosphoprotein 2, 24kDa 0.489838
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 0.489447
TMED2 transmembrane emp24 domain trafficking protein 2 0.483986
SMAD4 SMAD family member 4 0.482428
PLA2G1B phospholipase A2, group IB (pancreas) 0.481259
MMP9 matrix metallopeptidase 9 0.478145
UCMA upper zone of growth plate and cartilage matrix associated 0.468824
SMAD2 SMAD family member 2 0.468048
BAX BCL2-associated X protein 0.467273
EGR1 early growth response 1 0.466498
ITGA8 integrin, alpha 8 0.4576
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.452198
PKDCC protein kinase domain containing, cytoplasmic 0.451042
PBX1 pre-B-cell leukemia homeobox 1 0.446038
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 0.445653
WNT10B wingless-type MMTV integration site family, member 10B 0.444115
FST follistatin 0.441426
PGF placental growth factor 0.438356
IGFBP5 insulin-like growth factor binding protein 5 0.435672
MGAM maltase-glucoamylase 0.433757
SEBOX SEBOX homeobox 0.428401
NPR2 natriuretic peptide receptor 2 0.428018
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.427636
PCDH8 protocadherin 8 0.426109
PPARG peroxisome proliferator-activated receptor gamma 0.423054
KCNU1 potassium channel, subfamily U, member 1 0.422292
MAPK3 mitogen-activated protein kinase 3 0.42191
OMD osteomodulin 0.421148
SESN3 sestrin 3 0.420766
MELK maternal embryonic leucine zipper kinase 0.420004
TMEM176B transmembrane protein 176B 0.420004
GLRX5 glutaredoxin 5 0.413912
EAPP E2F-associated phosphoprotein 0.413532
WASF2 WAS protein family, member 2 0.408592
CCND1 cyclin D1 0.407832
PRKD1 protein kinase D1 0.40328
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.402523
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.399492
S100A6 S100 calcium binding protein A6 0.3976
KNG1 kininogen 1 0.397222
IL17B interleukin 17B 0.394197
SIRT1 sirtuin 1 0.393064
SFRP4 secreted frizzled-related protein 4 0.388535
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.387027
TAZ tafazzin 0.386273
NFIL3 nuclear factor, interleukin 3 regulated 0.384013
CLCN4 chloride channel, voltage-sensitive 4 0.381003
SMAD6 SMAD family member 6 0.380627
SRCAP Snf2-related CREBBP activator protein 0.380251
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 0.378372
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.377996
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.377996
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.377996
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.37687
LECT2 leukocyte cell-derived chemotaxin 2 0.375743
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.375368
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 0.373868
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 0.37087
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa 0.365633
DCN decorin 0.36302
MOSPD3 motile sperm domain containing 3 0.360409
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 0.359292
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 0.358546
MMP2 matrix metallopeptidase 2 0.35557
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.352969
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.346668
CUTA cutA divalent cation tolerance homolog (E. coli) 0.345188
WWTR1 WW domain containing transcription regulator 1 0.340388
LTBP3 latent transforming growth factor beta binding protein 3 0.330827
PTGFRN prostaglandin F2 receptor inhibitor 0.327164
IL17RE interleukin 17 receptor E 0.324605
NCAPD2 non-SMC condensin I complex, subunit D2 0.323144
RAB24 RAB24, member RAS oncogene family 0.321685
EI24 etoposide induced 2.4 0.319134
LTBP2 latent transforming growth factor beta binding protein 2 0.31877
ETF1 eukaryotic translation termination factor 1 0.314409
HIST1H4I histone cluster 1, H4i 0.310059
HIST1H4F histone cluster 1, H4f 0.310059
HIST2H4A histone cluster 2, H4a 0.310059
HIST1H4H histone cluster 1, H4h 0.310059
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.310059
HIST1H4B histone cluster 1, H4b 0.310059
HIST1H4J histone cluster 1, H4j 0.310059
HIST1H4K histone cluster 1, H4k 0.310059
HIST2H4B histone cluster 2, H4b 0.310059
HIST1H4C histone cluster 1, H4c 0.310059
HIST1H4A histone cluster 1, H4a 0.310059
HIST1H4E histone cluster 1, H4e 0.310059
HIST1H4D histone cluster 1, H4d 0.310059
LUM lumican 0.308974
HIST4H4 histone cluster 4, H4 0.308612
HIST1H4L histone cluster 1, H4l 0.308612
ELK1 ELK1, member of ETS oncogene family 0.307528
CCAR1 cell division cycle and apoptosis regulator 1 0.305722
HNF4A hepatocyte nuclear factor 4, alpha 0.303919
FGFR1 fibroblast growth factor receptor 1 0.301758
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 0.301398
MYOD1 myogenic differentiation 1 0.301039
CNN2 calponin 2 0.300679
DKK2 dickkopf WNT signaling pathway inhibitor 2 0.300679
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.30032
VEGFA vascular endothelial growth factor A 0.29996
IL17RD interleukin 17 receptor D 0.299242
MAB21L1 mab-21-like 1 (C. elegans) 0.296372
HSPA4 heat shock 70kDa protein 4 0.295655
NRP1 neuropilin 1 0.295655
RGS2 regulator of G-protein signaling 2 0.291722
FLT1 fms-related tyrosine kinase 1 0.290295
ELOVL3 ELOVL fatty acid elongase 3 0.28887
CALCR calcitonin receptor 0.287803
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.286026
MMP1 matrix metallopeptidase 1 0.283545
PDCL3 phosducin-like 3 0.278955
CAST calpastatin 0.272997
TUB tubby bipartite transcription factor 0.272533
ROR2 receptor tyrosine kinase-like orphan receptor 2 0.267791
HIST1H3G histone cluster 1, H3g 0.266757
HIST1H3D histone cluster 1, H3d 0.266757
HIST1H3J histone cluster 1, H3j 0.266757
HIST1H3F histone cluster 1, H3f 0.266757
HIST1H3I histone cluster 1, H3i 0.266757
HIST1H3B histone cluster 1, H3b 0.266413
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.265725
TUBB2B tubulin, beta 2B class IIb 0.264696
DVL2 dishevelled segment polarity protein 2 0.263327
WNT5A wingless-type MMTV integration site family, member 5A 0.255234
SHH sonic hedgehog 0.253908
DLX3 distal-less homeobox 3 0.251934
CALCA calcitonin-related polypeptide alpha 0.246442
SESN1 sestrin 1 0.244545
SATB2 SATB homeobox 2 0.24052
AXIN2 axin 2 0.240216
NPSR1 neuropeptide S receptor 1 0.239913
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 0.23961
CHRD chordin 0.239307
ADCY2 adenylate cyclase 2 (brain) 0.238108
GDF5 growth differentiation factor 5 0.235457
MMD monocyte to macrophage differentiation-associated 0.235167
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.234878
HIST1H3E histone cluster 1, H3e 0.234016
GLO1 glyoxalase I 0.233731
LOXL2 lysyl oxidase-like 2 0.23176
CNOT8 CCR4-NOT transcription complex, subunit 8 0.230931
MAP2K3 mitogen-activated protein kinase kinase 3 0.229032
LOXL1 lysyl oxidase-like 1 0.22797
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.227707
HIST1H3C histone cluster 1, H3c 0.224398
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 0.223906
HIST1H3H histone cluster 1, H3h 0.223906
BMPR1A bone morphogenetic protein receptor, type IA 0.223419
RNF11 ring finger protein 11 0.22246
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.220831
ULK1 unc-51 like autophagy activating kinase 1 0.220152
HIST1H3A histone cluster 1, H3a 0.219928
CLEC2D C-type lectin domain family 2, member D 0.219485
GHSR growth hormone secretagogue receptor 0.219485
ANXA5 annexin A5 0.21883
CREB3L3 cAMP responsive element binding protein 3-like 3 0.218613
CDC6 cell division cycle 6 0.217554
CYR61 cysteine-rich, angiogenic inducer, 61 0.216126
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 0.214388
CREB3L2 cAMP responsive element binding protein 3-like 2 0.214202
ACVR1 activin A receptor, type I 0.21365
RAP2B RAP2B, member of RAS oncogene family 0.213291
GFER growth factor, augmenter of liver regeneration 0.212936
RAB1B RAB1B, member RAS oncogene family 0.212936
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.212413
SAR1A secretion associated, Ras related GTPase 1A 0.179505