| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the orlistat-6388 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ABHD2 | abhydrolase domain containing 2 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| AMPD3 | adenosine monophosphate deaminase 3 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APOC1 | apolipoprotein C-I |
| APOE | apolipoprotein E |
| ARHGAP44 | Rho GTPase activating protein 44 |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| ATP6AP2 | ATPase, H+ transporting, lysosomal accessory protein 2 |
| BRCA2 | breast cancer 2, early onset |
| C19ORF57 | chromosome 19 open reading frame 57 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CCDC134 | coiled-coil domain containing 134 |
| CCDC9 | coiled-coil domain containing 9 |
| CLTC | clathrin, heavy chain (Hc) |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COL14A1 | collagen, type XIV, alpha 1 |
| COPE | coatomer protein complex, subunit epsilon |
| CORT | cortistatin |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 |
| EPHA5 | EPH receptor A5 |
| EPS8L1 | EPS8-like 1 |
| ETV1 | ets variant 1 |
| FAM46C | family with sequence similarity 46, member C |
| FAM63B | family with sequence similarity 63, member B |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FOSL2 | FOS-like antigen 2 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GNAS | GNAS complex locus |
| GPR1 | G protein-coupled receptor 1 |
| GRIA4 | glutamate receptor, ionotropic, AMPA 4 |
| GRM8 | glutamate receptor, metabotropic 8 |
| HIRA | histone cell cycle regulator |
| HRG | histidine-rich glycoprotein |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IL16 | interleukin 16 |
| INSIG1 | insulin induced gene 1 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| JAG1 | jagged 1 |
| KLHL25 | kelch-like family member 25 |
| LAMA4 | laminin, alpha 4 |
| LIMK2 | LIM domain kinase 2 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAGOH2P | mago-nashi homolog 2, pseudogene |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MAP2 | microtubule-associated protein 2 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MED16 | mediator complex subunit 16 |
| MEFV | Mediterranean fever |
| MSX2 | msh homeobox 2 |
| MUC13 | mucin 13, cell surface associated |
| MUC3A | mucin 3A, cell surface associated |
| NEB | nebulin |
| NEBL | nebulette |
| NPR3 | natriuretic peptide receptor 3 |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| ONECUT2 | one cut homeobox 2 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PEX5L | peroxisomal biogenesis factor 5-like |
| PIAS4 | protein inhibitor of activated STAT, 4 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLXNA3 | plexin A3 |
| PODXL2 | podocalyxin-like 2 |
| POLL | polymerase (DNA directed), lambda |
| PPARD | peroxisome proliferator-activated receptor delta |
| RBM17 | RNA binding motif protein 17 |
| REEP2 | receptor accessory protein 2 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RFPL1S | RFPL1 antisense RNA 1 |
| RFPL3 | ret finger protein-like 3 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SEMA4F | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F |
| SFTPB | surfactant protein B |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SSTR4 | somatostatin receptor 4 |
| SUGP1 | SURP and G patch domain containing 1 |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TBXA2R | thromboxane A2 receptor |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TSPAN2 | tetraspanin 2 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WAS | Wiskott-Aldrich syndrome |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZNF154 | zinc finger protein 154 |
| ZNF224 | zinc finger protein 224 |
| ZNF280A | zinc finger protein 280A |
| Symbol | Name |
|---|---|
| ACOXL | acyl-CoA oxidase-like |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ALPK1 | alpha-kinase 1 |
| ALPK3 | alpha-kinase 3 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
| BEX4 | brain expressed, X-linked 4 |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CBX8 | chromobox homolog 8 |
| CCDC71 | coiled-coil domain containing 71 |
| CDK20 | cyclin-dependent kinase 20 |
| CFAP69 | cilia and flagella associated protein 69 |
| CHM | choroideremia (Rab escort protein 1) |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLSTN3 | calsyntenin 3 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CRMP1 | collapsin response mediator protein 1 |
| CYTH3 | cytohesin 3 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
| ECM1 | extracellular matrix protein 1 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FGF6 | fibroblast growth factor 6 |
| FLJ22184 | |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GGTLC1 | gamma-glutamyltransferase light chain 1 |
| GHR | growth hormone receptor |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GPALPP1 | GPALPP motifs containing 1 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| HOXC5 | homeobox C5 |
| HSPA1L | heat shock 70kDa protein 1-like |
| ICAM4 | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IMPG2 | interphotoreceptor matrix proteoglycan 2 |
| KIF13A | kinesin family member 13A |
| KLHL28 | kelch-like family member 28 |
| KRT4 | keratin 4, type II |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LRRC37BP1 | leucine rich repeat containing 37B pseudogene 1 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LYRM9 | LYR motif containing 9 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MEGF8 | multiple EGF-like-domains 8 |
| MEOX1 | mesenchyme homeobox 1 |
| MLXIPL | MLX interacting protein-like |
| MORN1 | MORN repeat containing 1 |
| MT1M | metallothionein 1M |
| MXRA8 | matrix-remodelling associated 8 |
| NDNF | neuron-derived neurotrophic factor |
| NUBP2 | nucleotide binding protein 2 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OR7C1 | olfactory receptor, family 7, subfamily C, member 1 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| OSMR | oncostatin M receptor |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PGAM2 | phosphoglycerate mutase 2 (muscle) |
| PGPEP1 | pyroglutamyl-peptidase I |
| PLA2G3 | phospholipase A2, group III |
| PPEF1 | protein phosphatase, EF-hand calcium binding domain 1 |
| PRL | prolactin |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAB40AL | RAB40A, member RAS oncogene family-like |
| REC8 | REC8 meiotic recombination protein |
| S100A3 | S100 calcium binding protein A3 |
| SEC14L5 | SEC14-like 5 (S. cerevisiae) |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| STRN | striatin, calmodulin binding protein |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TCF15 | transcription factor 15 (basic helix-loop-helix) |
| TDRD12 | tudor domain containing 12 |
| TOM1L2 | target of myb1-like 2 (chicken) |
| TSC22D4 | TSC22 domain family, member 4 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TUBA3C | tubulin, alpha 3c |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF215 | zinc finger protein 215 |
| ZNF286A | zinc finger protein 286A |
| ZNF343 | zinc finger protein 343 |
| ZNF442 | zinc finger protein 442 |
| ZNF506 | zinc finger protein 506 |
| ZNF606 | zinc finger protein 606 |
