origin recognition complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A multisubunit complex that is located at the replication origins of a chromosome. (Gene Ontology, GO_0000808)
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Genes

123 proteins co-occuring with the origin recognition complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CDC6 cell division cycle 6 3.01563
MCM2 minichromosome maintenance complex component 2 2.26511
MCM7 minichromosome maintenance complex component 7 2.23828
CDT1 chromatin licensing and DNA replication factor 1 2.10347
ORC3 origin recognition complex, subunit 3 1.92299
MUT methylmalonyl CoA mutase 1.66598
LRWD1 leucine-rich repeats and WD repeat domain containing 1 1.60826
MCM3 minichromosome maintenance complex component 3 1.57645
GMNN geminin, DNA replication inhibitor 1.47004
CDC7 cell division cycle 7 1.46778
DBF4 DBF4 zinc finger 1.46382
ORC5 origin recognition complex, subunit 5 1.44347
KAT7 K(lysine) acetyltransferase 7 1.38905
CDC45 cell division cycle 45 1.33685
ORC4 origin recognition complex, subunit 4 1.22308
CDK2 cyclin-dependent kinase 2 1.09238
ORC2 origin recognition complex, subunit 2 1.05942
MCM6 minichromosome maintenance complex component 6 1.01734
MCM10 minichromosome maintenance complex component 10 0.998086
LMNB2 lamin B2 0.914376
NXPE2 neurexophilin and PC-esterase domain family, member 2 0.907855
MCM4 minichromosome maintenance complex component 4 0.899962
NXPE4 neurexophilin and PC-esterase domain family, member 4 0.852502
PCNA proliferating cell nuclear antigen 0.804772
TEN1 TEN1 CST complex subunit 0.795604
DCANP1 dendritic cell-associated nuclear protein 0.791022
ORC1 origin recognition complex, subunit 1 0.785071
MCM5 minichromosome maintenance complex component 5 0.779126
EFNA5 ephrin-A5 0.763617
ORC6 origin recognition complex, subunit 6 0.682463
RCN3 reticulocalbin 3, EF-hand calcium binding domain 0.665962
ASPH aspartate beta-hydroxylase 0.64915
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 0.612471
RNASEH2B ribonuclease H2, subunit B 0.595593
KPNA6 karyopherin alpha 6 (importin alpha 7) 0.588037
OCM oncomodulin 0.584686
ATXN10 ataxin 10 0.574244
OCM2 oncomodulin 2 0.568001
HMGA1 high mobility group AT-hook 1 0.550186
MDN1 MDN1, midasin homolog (yeast) 0.548535
ZMYM3 zinc finger, MYM-type 3 0.544411
CBX5 chromobox homolog 5 0.542764
CBR1 carbonyl reductase 1 0.542764
TOP1 topoisomerase (DNA) I 0.542352
CINP cyclin-dependent kinase 2 interacting protein 0.537416
SERTAD1 SERTA domain containing 1 0.518981
RFC1 replication factor C (activator 1) 1, 145kDa 0.513677
DHFR dihydrofolate reductase 0.492157
GINS4 GINS complex subunit 4 (Sld5 homolog) 0.482064
MCM9 minichromosome maintenance complex component 9 0.468401
DKK4 dickkopf WNT signaling pathway inhibitor 4 0.461998
BRD2 bromodomain containing 2 0.457208
WDR83 WD repeat domain 83 0.453223
PXK PX domain containing serine/threonine kinase 0.425924
GAGE12F G antigen 12F 0.420428
GAGE12I G antigen 12I 0.416511
ALDOB aldolase B, fructose-bisphosphate 0.412992
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.41182
H3F3A H3 histone, family 3A 0.408309
H3F3B H3 histone, family 3B (H3.3B) 0.408309
TICAM2 toll-like receptor adaptor molecule 2 0.399751
PLK1 polo-like kinase 1 0.392775
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) 0.388523
ATR ATR serine/threonine kinase 0.377354
FOXG1 forkhead box G1 0.37045
KDM2A lysine (K)-specific demethylase 2A 0.354422
SMYD3 SET and MYND domain containing 3 0.353662
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.350243
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 0.350243
CCDC101 coiled-coil domain containing 101 0.335864
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 0.334356
DDAH2 dimethylarginine dimethylaminohydrolase 2 0.333979
SLBP stem-loop binding protein 0.323075
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) 0.322325
HIST1H4F histone cluster 1, H4f 0.309613
HIST1H4E histone cluster 1, H4e 0.309613
HIST2H4A histone cluster 2, H4a 0.309613
HIST1H4H histone cluster 1, H4h 0.309613
HIST1H4D histone cluster 1, H4d 0.309613
HIST1H4I histone cluster 1, H4i 0.309613
HIST2H4B histone cluster 2, H4b 0.309613
HIST1H4J histone cluster 1, H4j 0.309613
HIST1H4A histone cluster 1, H4a 0.309613
HIST1H4B histone cluster 1, H4b 0.309613
HIST1H4K histone cluster 1, H4k 0.309613
HIST1H4C histone cluster 1, H4c 0.309613
HIST1H4L histone cluster 1, H4l 0.30924
HIST4H4 histone cluster 4, H4 0.30924
ATM ATM serine/threonine kinase 0.303655
MBD4 methyl-CpG binding domain protein 4 0.296972
CDK1 cyclin-dependent kinase 1 0.288091
CKAP5 cytoskeleton associated protein 5 0.286614
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 0.279612
RAD50 RAD50 homolog (S. cerevisiae) 0.274468
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) 0.26239
CDC25A cell division cycle 25A 0.253291
DDB1 damage-specific DNA binding protein 1, 127kDa 0.250751
RECQL RecQ helicase-like 0.240996
RFC3 replication factor C (activator 1) 3, 38kDa 0.229888
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 0.228464
RFC5 replication factor C (activator 1) 5, 36.5kDa 0.227397
RFC4 replication factor C (activator 1) 4, 37kDa 0.226686
TOM1 target of myb1 (chicken) 0.221025
CEP152 centrosomal protein 152kDa 0.220673
CCDC88A coiled-coil domain containing 88A 0.219265
HARS histidyl-tRNA synthetase 0.21681
DNAH8 dynein, axonemal, heavy chain 8 0.212974
CCNA1 cyclin A1 0.210549
CALU calumenin 0.19733
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) 0.193394
CDC14A cell division cycle 14A 0.192423
ITM2B integral membrane protein 2B 0.190495
AKR1C3 aldo-keto reductase family 1, member C3 0.189222
RFC2 replication factor C (activator 1) 2, 40kDa 0.183631
PHF20 PHD finger protein 20 0.180634
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.167366
MSH4 mutS homolog 4 0.16477
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.159856
CHAF1A chromatin assembly factor 1, subunit A (p150) 0.159074
RECQL4 RecQ protein-like 4 0.157218
BACE1 beta-site APP-cleaving enzyme 1 0.144892
PRTN3 proteinase 3 0.141866
MPO myeloperoxidase 0.139308