ocular hypertension Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

175 genes co-occuring with the disease ocular hypertension in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 2.14328
PTGFR prostaglandin F receptor (FP) 1.49613
POU4F1 POU class 4 homeobox 1 1.42718
ZNF343 zinc finger protein 343 1.21219
OPN4 opsin 4 1.19834
GPR158 G protein-coupled receptor 158 1.10636
NARF nuclear prelamin A recognition factor 1.09545
PEX19 peroxisomal biogenesis factor 19 1.09377
OPTN optineurin 1.05807
CA2 carbonic anhydrase II 1.04293
SOX30 SRY (sex determining region Y)-box 30 1.01174
GATAD1 GATA zinc finger domain containing 1 0.997814
RABGAP1 RAB GTPase activating protein 1 0.997814
MARK1 MAP/microtubule affinity-regulating kinase 1 0.945354
LMX1B LIM homeobox transcription factor 1, beta 0.938704
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.924213
SRSF3 serine/arginine-rich splicing factor 3 0.877786
AADAT aminoadipate aminotransferase 0.866731
POU4F2 POU class 4 homeobox 2 0.860999
PER2 period circadian clock 2 0.841753
CCBL1 cysteine conjugate-beta lyase, cytoplasmic 0.833558
PDIA5 protein disulfide isomerase family A, member 5 0.824128
NLRP4 NLR family, pyrin domain containing 4 0.802385
AIF1 allograft inflammatory factor 1 0.797052
LINGO1 leucine rich repeat and Ig domain containing 1 0.76921
GAS1 growth arrest-specific 1 0.762271
PSD3 pleckstrin and Sec7 domain containing 3 0.74883
LIMK2 LIM domain kinase 2 0.736243
RTN4 reticulon 4 0.733811
RPIA ribose 5-phosphate isomerase A 0.72127
GHSR growth hormone secretagogue receptor 0.72127
BDNF brain-derived neurotrophic factor 0.709975
WDR36 WD repeat domain 36 0.709572
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.708364
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.702732
TSPO translocator protein (18kDa) 0.680297
SRSF9 serine/arginine-rich splicing factor 9 0.673917
PGF placental growth factor 0.658818
NGB neuroglobin 0.654463
ATP10A ATPase, class V, type 10A 0.624143
NGF nerve growth factor (beta polypeptide) 0.6214
FKBP5 FK506 binding protein 5 0.612401
DTNA dystrobrevin, alpha 0.603811
CA6 carbonic anhydrase VI 0.60264
POU4F3 POU class 4 homeobox 3 0.60186
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.597961
CNTF ciliary neurotrophic factor 0.597181
FOXC1 forkhead box C1 0.593674
GFAP glial fibrillary acidic protein 0.585108
RGCC regulator of cell cycle 0.583163
PRELP proline/arginine-rich end leucine-rich repeat protein 0.570329
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.566054
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 0.565666
SRSF5 serine/arginine-rich splicing factor 5 0.5645
AQP4 aquaporin 4 0.562558
TGFB2 transforming growth factor, beta 2 0.561781
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 0.558674
SLCO2A1 solute carrier organic anion transporter family, member 2A1 0.555568
CNOT2 CCR4-NOT transcription complex, subunit 2 0.547419
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.540442
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) 0.540442
GIN1 gypsy retrotransposon integrase 1 0.536183
PER1 period circadian clock 1 0.524202
SYCN syncollin 0.514956
FKBP4 FK506 binding protein 4, 59kDa 0.501144
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.499231
CA5A carbonic anhydrase VA, mitochondrial 0.491597
CRYAA crystallin, alpha A 0.483604
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.483604
CDH4 cadherin 4, type 1, R-cadherin (retinal) 0.475255
BIRC6 baculoviral IAP repeat containing 6 0.469576
ADORA1 adenosine A1 receptor 0.467684
PRSS21 protease, serine, 21 (testisin) 0.46655
EYS eyes shut homolog (Drosophila) 0.462772
KLHL2 kelch-like family member 2 0.459751
SENP1 SUMO1/sentrin specific peptidase 1 0.455978
OLFM4 olfactomedin 4 0.443171
OPCML opioid binding protein/cell adhesion molecule-like 0.442042
SAG S-antigen; retina and pineal gland (arrestin) 0.437906
ANGPTL7 angiopoietin-like 7 0.434899
ADORA2B adenosine A2b receptor 0.433772
ADCY10 adenylate cyclase 10 (soluble) 0.416896
FBXW2 F-box and WD repeat domain containing 2 0.416147
C1QB complement component 1, q subcomponent, B chain 0.415398
CD200R1 CD200 receptor 1 0.410161
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.407545
BSN bassoon presynaptic cytomatrix protein 0.401572
NTM neurotrimin 0.399707
GRIA3 glutamate receptor, ionotropic, AMPA 3 0.394491
SPRED1 sprouty-related, EVH1 domain containing 1 0.393001
TDP1 tyrosyl-DNA phosphodiesterase 1 0.384451
SMTNL1 smoothelin-like 1 0.37629
ADRB1 adrenoceptor beta 1 0.374068
SOAT1 sterol O-acyltransferase 1 0.369258
ADCY8 adenylate cyclase 8 (brain) 0.362978
HINT1 histidine triad nucleotide binding protein 1 0.362239
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.358551
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 0.353763
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 0.351187
NKX6-2 NK6 homeobox 2 0.349717
CA14 carbonic anhydrase XIV 0.345675
SCNN1B sodium channel, non voltage gated 1 beta subunit 0.333949
EPHB3 EPH receptor B3 0.333218
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa 0.333218
TMTC1 transmembrane and tetratricopeptide repeat containing 1 0.325187
SCAI suppressor of cancer cell invasion 0.317182
OMG oligodendrocyte myelin glycoprotein 0.316092
CDH5 cadherin 5, type 2 (vascular endothelium) 0.31464
CA13 carbonic anhydrase XIII 0.31464
MRAP melanocortin 2 receptor accessory protein 0.313189
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.308842
GRIA4 glutamate receptor, ionotropic, AMPA 4 0.305948
CAST calpastatin 0.300894
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.300533
CRYBB2 crystallin, beta B2 0.299452
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.298371
JUN jun proto-oncogene 0.298011
FN1 fibronectin 1 0.295851
EHF ets homologous factor 0.294413
GNAS GNAS complex locus 0.294053
VEGFA vascular endothelial growth factor A 0.289744
SYP synaptophysin 0.281868
TRIM37 tripartite motif containing 37 0.280796
BTNL2 butyrophilin-like 2 0.280439
GHRL ghrelin/obestatin prepropeptide 0.278654
CYCS cytochrome c, somatic 0.276514
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.275445
PYCR1 pyrroline-5-carboxylate reductase 1 0.272953
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 0.264785
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.258064
FZD1 frizzled class receptor 1 0.257711
DHDH dihydrodiol dehydrogenase (dimeric) 0.256652
PBK PDZ binding kinase 0.254888
RLBP1 retinaldehyde binding protein 1 0.254183
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.253479
FOS FBJ murine osteosarcoma viral oncogene homolog 0.25207
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.251366
HPN hepsin 0.247852
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.244696
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 0.242245
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 0.238752
CD80 CD80 molecule 0.238403
LARGE like-glycosyltransferase 0.238054
EPHB2 EPH receptor B2 0.237357
SCNN1G sodium channel, non voltage gated 1 gamma subunit 0.235616
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 0.235616
FES FES proto-oncogene, tyrosine kinase 0.23353
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.229716
ARSB arylsulfatase B 0.223509
GSTM3 glutathione S-transferase mu 3 (brain) 0.220081
CA12 carbonic anhydrase XII 0.214975
CA7 carbonic anhydrase VII 0.212945
CA5B carbonic anhydrase VB, mitochondrial 0.210589
CA1 carbonic anhydrase I 0.210253
OCLN occludin 0.204263
OCA2 oculocutaneous albinism II 0.203275
NGFR nerve growth factor receptor 0.197742
OR10K1 olfactory receptor, family 10, subfamily K, member 1 0.196139
MARK3 MAP/microtubule affinity-regulating kinase 3 0.192971
RPTOR regulatory associated protein of MTOR, complex 1 0.189551
SNCG synuclein, gamma (breast cancer-specific protein 1) 0.18621
CRYGS crystallin, gamma S 0.18591
CD200 CD200 molecule 0.18472
RCVRN recoverin 0.184128
WARS tryptophanyl-tRNA synthetase 0.182086
ROCK1P1 Rho-associated, coiled-coil containing protein kinase 1 pseudogene 1 0.174617
GDF5 growth differentiation factor 5 0.171785
IGLV2-14 immunoglobulin lambda variable 2-14 0.171535
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.164786
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.163523
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.163523
RTN4R reticulon 4 receptor 0.162505
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1 0.158434
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 0.158266
CALCR calcitonin receptor 0.157602