octopamine-3112 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the octopamine-3112 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABI2 abl-interactor 2
ACTN2 actinin, alpha 2
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
ALDOB aldolase B, fructose-bisphosphate
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARID1A AT rich interactive domain 1A (SWI-like)
ATXN3 ataxin 3
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BTN2A2 butyrophilin, subfamily 2, member A2
C11ORF16 chromosome 11 open reading frame 16
C1QL1 complement component 1, q subcomponent-like 1
C4ORF19 chromosome 4 open reading frame 19
CAV1 caveolin 1, caveolae protein, 22kDa
CD47 CD47 molecule
CDRT1 CMT1A duplicated region transcript 1
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CHD9 chromodomain helicase DNA binding protein 9
CNGB1 cyclic nucleotide gated channel beta 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CNTNAP1 contactin associated protein 1
COL21A1 collagen, type XXI, alpha 1
CRHR1 corticotropin releasing hormone receptor 1
CRTAM cytotoxic and regulatory T cell molecule
CTSE cathepsin E
DCAF15 DDB1 and CUL4 associated factor 15
DPYSL3 dihydropyrimidinase-like 3
DST dystonin
ENDOD1 endonuclease domain containing 1
FAM127B family with sequence similarity 127, member B
FAM76A family with sequence similarity 76, member A
FBXO4 F-box protein 4
FJX1 four jointed box 1 (Drosophila)
FOSL1 FOS-like antigen 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GNLY granulysin
GPC3 glypican 3
HFE hemochromatosis
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA2 heat shock 70kDa protein 2
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IGF2-AS IGF2 antisense RNA
ITGB8 integrin, beta 8
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KIDINS220 kinase D-interacting substrate, 220kDa
KLF3 Kruppel-like factor 3 (basic)
LRRC23 leucine rich repeat containing 23
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MBNL3 muscleblind-like splicing regulator 3
MED16 mediator complex subunit 16
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NR2F1 nuclear receptor subfamily 2, group F, member 1
NRL neural retina leucine zipper
PBX2 pre-B-cell leukemia homeobox 2
PDCD2 programmed cell death 2
PEG10 paternally expressed 10
PLCG1 phospholipase C, gamma 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POU6F1 POU class 6 homeobox 1
PRDM1 PR domain containing 1, with ZNF domain
PRKCE protein kinase C, epsilon
PRKCH protein kinase C, eta
PRPF18 pre-mRNA processing factor 18
PRUNE2 prune homolog 2 (Drosophila)
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAB2A RAB2A, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RIF1 replication timing regulatory factor 1
RPL10L ribosomal protein L10-like
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RYR1 ryanodine receptor 1 (skeletal)
SCLY selenocysteine lyase
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SH3BGR SH3 domain binding glutamate-rich protein
SHB Src homology 2 domain containing adaptor protein B
SIPA1 signal-induced proliferation-associated 1
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC6A16 solute carrier family 6, member 16
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SYNDIG1 synapse differentiation inducing 1
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TEX40 testis expressed 40
THBS1 thrombospondin 1
TPMT thiopurine S-methyltransferase
TRPS1 trichorhinophalangeal syndrome I
TSC22D4 TSC22 domain family, member 4
TTC30A tetratricopeptide repeat domain 30A
ZER1 zyg-11 related, cell cycle regulator
ZNF132 zinc finger protein 132
ZNF287 zinc finger protein 287
ZNF473 zinc finger protein 473
ZNF696 zinc finger protein 696
ZXDB zinc finger, X-linked, duplicated B
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ALS2CL ALS2 C-terminal like
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
BIK BCL2-interacting killer (apoptosis-inducing)
C17ORF80 chromosome 17 open reading frame 80
C1ORF105 chromosome 1 open reading frame 105
C1ORF159 chromosome 1 open reading frame 159
C22ORF29 chromosome 22 open reading frame 29
CAPN15 calpain 15
CCDC88C coiled-coil domain containing 88C
CD70 CD70 molecule
CENPB centromere protein B, 80kDa
CENPO centromere protein O
CEP170B centrosomal protein 170B
CLDN15 claudin 15
CLDN7 claudin 7
COL9A2 collagen, type IX, alpha 2
CORT cortistatin
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
E2F1 E2F transcription factor 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FOXO4 forkhead box O4
FZD6 frizzled class receptor 6
GAA glucosidase, alpha; acid
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GSTA4 glutathione S-transferase alpha 4
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H1T histone cluster 1, H1t
HRAS Harvey rat sarcoma viral oncogene homolog
ICK intestinal cell (MAK-like) kinase
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IL3RA interleukin 3 receptor, alpha (low affinity)
IQSEC2 IQ motif and Sec7 domain 2
IRF7 interferon regulatory factor 7
ITPKC inositol-trisphosphate 3-kinase C
JMJD4 jumonji domain containing 4
KCNK5 potassium channel, two pore domain subfamily K, member 5
KIAA0753 KIAA0753
KLHL28 kelch-like family member 28
LRRC6 leucine rich repeat containing 6
LTC4S leukotriene C4 synthase
MEFV Mediterranean fever
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTHFSD methenyltetrahydrofolate synthetase domain containing
MVP major vault protein
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NAT6 N-acetyltransferase 6 (GCN5-related)
NCALD neurocalcin delta
NDE1 nudE neurodevelopment protein 1
NECAB3 N-terminal EF-hand calcium binding protein 3
NFE2L3 nuclear factor, erythroid 2-like 3
NINJ2 ninjurin 2
NIPAL2 NIPA-like domain containing 2
NOL10 nucleolar protein 10
NT5M 5',3'-nucleotidase, mitochondrial
NUBP2 nucleotide binding protein 2
NXPH4 neurexophilin 4
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PKD2L2 polycystic kidney disease 2-like 2
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCD1 phospholipase C, delta 1
PLCL1 phospholipase C-like 1
POM121L2 POM121 transmembrane nucleoporin-like 2
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
RAB3D RAB3D, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RFPL1S RFPL1 antisense RNA 1
RNF126P1 ring finger protein 126 pseudogene 1
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SLAMF7 SLAM family member 7
SLC12A8 solute carrier family 12, member 8
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC35F6 solute carrier family 35, member F6
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STBD1 starch binding domain 1
STEAP3 STEAP family member 3, metalloreductase
TERT telomerase reverse transcriptase
TESK1 testis-specific kinase 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM104 transmembrane protein 104
TMEM180 transmembrane protein 180
TMEM184C transmembrane protein 184C
TMUB2 transmembrane and ubiquitin-like domain containing 2
TRABD TraB domain containing
UBTD1 ubiquitin domain containing 1
ZC3H12A zinc finger CCCH-type containing 12A
ZC4H2 zinc finger, C4H2 domain containing
ZFHX3 zinc finger homeobox 3
ZNF177 zinc finger protein 177
ZNF778 zinc finger protein 778