obstructive lung disease Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0006536
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Genes

100 genes associated with the obstructive lung disease phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 1.63258
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.4475
TTC41P tetratricopeptide repeat domain 41, pseudogene 1.35805
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 1.35524
MAPK10 mitogen-activated protein kinase 10 1.34749
TLN2 talin 2 1.30864
HYKK hydroxylysine kinase 1.30781
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 1.29386
SLC39A10 solute carrier family 39 (zinc transporter), member 10 1.22695
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit 1.2221
PRKCH protein kinase C, eta 1.22185
THSD4 thrombospondin, type I, domain containing 4 1.15352
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) 1.12851
LOC284294 uncharacterized LOC284294 1.0674
SPATA13 spermatogenesis associated 13 1.05869
DCDC2 doublecortin domain containing 2 1.05869
RARB retinoic acid receptor, beta 1.05066
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 1.04712
PTPRD protein tyrosine phosphatase, receptor type, D 1.04365
TMEM254 transmembrane protein 254 1.02229
CALN1 calneuron 1 1.00059
CREB5 cAMP responsive element binding protein 5 1.00059
ADGRG6 adhesion G protein-coupled receptor G6 0.969142
FAM13A family with sequence similarity 13, member A 0.964823
SEZ6L seizure related 6 homolog (mouse)-like 0.919744
SRP72 signal recognition particle 72kDa 0.919744
TBCK TBC1 domain containing kinase 0.899912
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.868241
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 0.868241
SEPT9 septin 9 0.855449
MAP3K13 mitogen-activated protein kinase kinase kinase 13 0.855449
ANXA11 annexin A11 0.844241
HLA-C major histocompatibility complex, class I, C 0.808951
RAB4B RAB4B, member RAS oncogene family 0.650124
SFTPD surfactant protein D 0.615522
PSORS1C1 psoriasis susceptibility 1 candidate 1 0.60335
IREB2 iron-responsive element binding protein 2 0.542759
FTO fat mass and obesity associated 0.522136
RNF150 ring finger protein 150 0.495598
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 0.462607
CDYL chromodomain protein, Y-like 0.4604
PLCE1 phospholipase C, epsilon 1 0.450694
ANXA5 annexin A5 0.443208
FAM227B family with sequence similarity 227, member B 0.429707
MIR99AHG mir-99a-let-7c cluster host gene 0.424122
FGF7 fibroblast growth factor 7 0.423565
COL1A2 collagen, type I, alpha 2 0.413807
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.408206
JAKMIP3 Janus kinase and microtubule interacting protein 3 0.408206
CNTN5 contactin 5 0.4074
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.407192
EYA1 EYA transcriptional coactivator and phosphatase 1 0.406588
MAST3 microtubule associated serine/threonine kinase 3 0.40559
SERINC5 serine incorporator 5 0.403564
NTM neurotrimin 0.403073
HYDIN HYDIN, axonemal central pair apparatus protein 0.403073
KAZN kazrin, periplakin interacting protein 0.403073
WWTR1 WW domain containing transcription regulator 1 0.402811
GSG1L GSG1-like 0.398939
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.397703
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1 0.396823
MLF1 myeloid leukemia factor 1 0.395556
FOXP1 forkhead box P1 0.394095
ADARB1 adenosine deaminase, RNA-specific, B1 0.39398
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.393867
MIA2 melanoma inhibitory activity 2 0.393472
GFM1 G elongation factor, mitochondrial 1 0.393258
LXN latexin 0.392761
UST uronyl-2-sulfotransferase 0.392325
SCNN1B sodium channel, non voltage gated 1 beta subunit 0.391185
MEAF6 MYST/Esa1-associated factor 6 0.390478
EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1 0.390413
PLAGL1 pleiomorphic adenoma gene-like 1 0.390348
CSMD1 CUB and Sushi multiple domains 1 0.389573
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa 0.389279
ATP11A ATPase, class VI, type 11A 0.389106
LRRTM4 leucine rich repeat transmembrane neuronal 4 0.389077
ERBB4 erb-b2 receptor tyrosine kinase 4 0.387017
SDC2 syndecan 2 0.386905
IL17RA interleukin 17 receptor A 0.386849
SIAH3 siah E3 ubiquitin protein ligase family member 3 0.386383
SGCZ sarcoglycan, zeta 0.385987
RAB3C RAB3C, member RAS oncogene family 0.385478
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.38528
C6ORF58 chromosome 6 open reading frame 58 0.384518
ROPN1 rhophilin associated tail protein 1 0.381963
CNTN4 contactin 4 0.381724
STMN2 stathmin 2 0.381295
STK39 serine threonine kinase 39 0.380407
MYO18B myosin XVIIIB 0.380283
AKAP13 A kinase (PRKA) anchor protein 13 0.380037
STON2 stonin 2 0.379327
OFCC1 orofacial cleft 1 candidate 1 0.37931
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 0.378623
PDE1A phosphodiesterase 1A, calmodulin-dependent 0.3783
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 0.377822
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 0.377662
PAX8 paired box 8 0.377561
SUSD4 sushi domain containing 4 0.377264
GNG4 guanine nucleotide binding protein (G protein), gamma 4 0.376594