obesity Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description OMIM mapping confirmed by DO. [SN]. (Human Disease Ontology, DOID_9970)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0001513
Similar Terms
Downloads & Tools

Genes

213 genes associated with the obesity phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ADNP activity-dependent neuroprotector homeobox
AIP aryl hydrocarbon receptor interacting protein
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALMS1 Alstrom syndrome protein 1
ANOS1 anosmin 1
APOE apolipoprotein E
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARL6 ADP-ribosylation factor-like 6
ARMC5 armadillo repeat containing 5
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BBIP1 BBSome interacting protein 1
BBS1 Bardet-Biedl syndrome 1
BBS10 Bardet-Biedl syndrome 10
BBS12 Bardet-Biedl syndrome 12
BBS2 Bardet-Biedl syndrome 2
BBS4 Bardet-Biedl syndrome 4
BBS5 Bardet-Biedl syndrome 5
BBS7 Bardet-Biedl syndrome 7
BBS9 Bardet-Biedl syndrome 9
BDNF brain-derived neurotrophic factor
BEST1 bestrophin 1
BLK BLK proto-oncogene, Src family tyrosine kinase
C2ORF71 chromosome 2 open reading frame 71
C8ORF37 chromosome 8 open reading frame 37
CA4 carbonic anhydrase IV
CANT1 calcium activated nucleotidase 1
CDHR1 cadherin-related family member 1
CDKL5 cyclin-dependent kinase-like 5
CEP164 centrosomal protein 164kDa
CEP290 centrosomal protein 290kDa
CERKL ceramide kinase-like
CHD7 chromodomain helicase DNA binding protein 7
CLIP2 CAP-GLY domain containing linker protein 2
CLRN1 clarin 1
CNGA1 cyclic nucleotide gated channel alpha 1
CNGB1 cyclic nucleotide gated channel beta 1
CRB1 crumbs family member 1, photoreceptor morphogenesis associated
CREBBP CREB binding protein
CRX cone-rod homeobox
CTSH cathepsin H
CUL4B cullin 4B
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DHDDS dehydrodolichyl diphosphate synthase
DUSP6 dual specificity phosphatase 6
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ELN elastin
EYS eyes shut homolog (Drosophila)
FAM161A family with sequence similarity 161, member A
FEZF1 FEZ family zinc finger 1
FGF17 fibroblast growth factor 17
FGF8 fibroblast growth factor 8 (androgen-induced)
FGFR1 fibroblast growth factor receptor 1
FGFR3 fibroblast growth factor receptor 3
FLII flightless I homolog (Drosophila)
FLRT3 fibronectin leucine rich transmembrane protein 3
FMR1 fragile X mental retardation 1
FOXG1 forkhead box G1
FSCN2 fascin actin-bundling protein 2, retinal
FTO fat mass and obesity associated
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GATA4 GATA binding protein 4
GHR growth hormone receptor
GNAS GNAS complex locus
GNAS-AS1 GNAS antisense RNA 1
GTF2I general transcription factor IIi
GTF2IRD1 GTF2I repeat domain containing 1
GUCA1B guanylate cyclase activator 1B (retina)
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HCRT hypocretin (orexin) neuropeptide precursor
HDAC4 histone deacetylase 4
HDAC8 histone deacetylase 8
HESX1 HESX homeobox 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
IDH3B isocitrate dehydrogenase 3 (NAD+) beta
IFT172 intraflagellar transport 172
IFT27 intraflagellar transport 27
IL17RD interleukin 17 receptor D
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
IMPG2 interphotoreceptor matrix proteoglycan 2
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KDM6A lysine (K)-specific demethylase 6A
KIF7 kinesin family member 7
KISS1R KISS1 receptor
KIZ kizuna centrosomal protein
KLHL7 kelch-like family member 7
KMT2D lysine (K)-specific methyltransferase 2D
LEP leptin
LEPR leptin receptor
LIMK1 LIM domain kinase 1
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
LRP5 low density lipoprotein receptor-related protein 5
LZTFL1 leucine zipper transcription factor-like 1
MAGEL2 melanoma antigen family L2
MAK male germ cell-associated kinase
MAN1B1 mannosidase, alpha, class 1B, member 1
MC4R melanocortin 4 receptor
MECP2 methyl CpG binding protein 2
MEGF8 multiple EGF-like-domains 8
MERTK MER proto-oncogene, tyrosine kinase
MKKS McKusick-Kaufman syndrome
MKS1 Meckel syndrome, type 1
MOG myelin oligodendrocyte glycoprotein
MPST mercaptopyruvate sulfurtransferase
MTFMT mitochondrial methionyl-tRNA formyltransferase
NDN necdin, melanoma antigen (MAGE) family member
NEK2 NIMA-related kinase 2
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NIPBL Nipped-B homolog (Drosophila)
NPHP1 nephronophthisis 1 (juvenile)
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR2E3 nuclear receptor subfamily 2, group E, member 3
NRL neural retina leucine zipper
NSD1 nuclear receptor binding SET domain protein 1
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
NTNG1 netrin G1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OFD1 oral-facial-digital syndrome 1
OTX2 orthodenticle homeobox 2
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PAX6 paired box 6
PCNT pericentrin
PCSK1 proprotein convertase subtilisin/kexin type 1
PDE11A phosphodiesterase 11A
PDE4D phosphodiesterase 4D, cAMP-specific
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma
PDE8B phosphodiesterase 8B
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1
PHF6 PHD finger protein 6
POMC proopiomelanocortin
PPARG peroxisome proliferator-activated receptor gamma
PRCD progressive rod-cone degeneration
PRDM16 PR domain containing 16
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PROK2 prokineticin 2
PROKR2 prokineticin receptor 2
PROM1 prominin 1
PRPF3 pre-mRNA processing factor 3
PRPF31 pre-mRNA processing factor 31
PRPF4 pre-mRNA processing factor 4
PRPF6 pre-mRNA processing factor 6
PRPF8 pre-mRNA processing factor 8
PRPH2 peripherin 2 (retinal degeneration, slow)
PTEN phosphatase and tensin homolog
RAB23 RAB23, member RAS oncogene family
RAD21 RAD21 homolog (S. pombe)
RAI1 retinoic acid induced 1
RBP3 retinol binding protein 3, interstitial
RDH12 retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
RFC2 replication factor C (activator 1) 2, 40kDa
RGR retinal G protein coupled receptor
RHO rhodopsin
RLBP1 retinaldehyde binding protein 1
ROM1 retinal outer segment membrane protein 1
RP1 retinitis pigmentosa 1 (autosomal dominant)
RP2 retinitis pigmentosa 2 (X-linked recessive)
RP9 retinitis pigmentosa 9 (autosomal dominant)
RPE65 retinal pigment epithelium-specific protein 65kDa
RPGR retinitis pigmentosa GTPase regulator
SAG S-antigen; retina and pineal gland (arrestin)
SDCCAG8 serologically defined colon cancer antigen 8
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SH2B1 SH2B adaptor protein 1
SHANK3 SH3 and multiple ankyrin repeat domains 3
SIM1 single-minded family bHLH transcription factor 1
SKI SKI proto-oncogene
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC7A14 solute carrier family 7, member 14
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SMAD4 SMAD family member 4
SMC1A structural maintenance of chromosomes 1A
SMC3 structural maintenance of chromosomes 3
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRPN small nuclear ribonucleoprotein polypeptide N
SOX10 SRY (sex determining region Y)-box 10
SOX2 SRY (sex determining region Y)-box 2
SOX3 SRY (sex determining region Y)-box 3
SPATA7 spermatogenesis associated 7
SPG11 spastic paraplegia 11 (autosomal recessive)
SPRY4 sprouty homolog 4 (Drosophila)
STX16 syntaxin 16
TACR3 tachykinin receptor 3
TBL2 transducin (beta)-like 2
TBX1 T-box 1
TBX3 T-box 3
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRAPPC9 trafficking protein particle complex 9
TRIM32 tripartite motif containing 32
TTC8 tetratricopeptide repeat domain 8
TUB tubby bipartite transcription factor
TULP1 tubby like protein 1
UBE3A ubiquitin protein ligase E3A
USH2A Usher syndrome 2A (autosomal recessive, mild)
VPS13B vacuolar protein sorting 13 homolog B (yeast)
VSX1 visual system homeobox 1
WDPCP WD repeat containing planar cell polarity effector
WDR11 WD repeat domain 11
WDR34 WD repeat domain 34
WT1 Wilms tumor 1
XYLT1 xylosyltransferase I
ZBTB20 zinc finger and BTB domain containing 20
ZDHHC15 zinc finger, DHHC-type containing 15
ZNF365 zinc finger protein 365
ZNF513 zinc finger protein 513