obesity Gene Set

Dataset DISEASES Experimental Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description OMIM mapping confirmed by DO. [SN]. (Human Disease Ontology, DOID_9970)
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Genes

105 genes associated with the disease obesity in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
COBLL1 cordon-bleu WH2 repeat protein-like 1 1.86862
RSPO3 R-spondin 3 1.82071
VEGFA vascular endothelial growth factor A 1.61356
TBX15 T-box 15 1.55692
NFE2L3 nuclear factor, erythroid 2-like 3 1.55524
DNM3 dynamin 3 1.24299
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 1.24299
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 1.22898
LIN7C lin-7 homolog C (C. elegans) 1.20753
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 1.14929
GNPDA2 glucosamine-6-phosphate deaminase 2 1.13588
HOXC13 homeobox C13 1.1139
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 0.790827
ZNRF3 zinc and ring finger 3 0.774217
SH2B1 SH2B adaptor protein 1 0.752991
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.682635
NISCH nischarin 0.670996
OLFM4 olfactomedin 4 0.602429
CPEB4 cytoplasmic polyadenylation element binding protein 4 0.602429
HOXB5 homeobox B5 0.572184
MTCH2 mitochondrial carrier 2 0.561725
MSRA methionine sulfoxide reductase A 0.5306
PAX5 paired box 5 0.5306
KCTD15 potassium channel tetramerization domain containing 15 0.486425
RPS17P5 ribosomal protein S17 pseudogene 5 0.464771
SLC30A10 solute carrier family 30, member 10 0.464771
NCAM2 neural cell adhesion molecule 2 0.449873
MRPS22 mitochondrial ribosomal protein S22 0.438544
NRXN3 neurexin 3 0.438544
NEGR1 neuronal growth regulator 1 0.429338
SPRY2 sprouty homolog 2 (Drosophila) 0.4215
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 0.414708
FTO fat mass and obesity associated 0.403461
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.403461
CHD2 chromodomain helicase DNA binding protein 2 0.368757
GDAP1 ganglioside induced differentiation associated protein 1 0.368757
INHBB inhibin, beta B 0.368757
MC4R melanocortin 4 receptor 0.368757
ARG1 arginase 1 0.345945
NPC1 Niemann-Pick disease, type C1 0.345945
TBCE tubulin folding cofactor E 0.345945
BCDIN3D BCDIN3 domain containing 0.327313
SOX6 SRY (sex determining region Y)-box 6 0.327313
TTC28 tetratricopeptide repeat domain 28 0.285417
PCDH9 protocadherin 9 0.285417
LHFPL3 lipoma HMGIC fusion partner-like 3 0.285417
WWOX WW domain containing oxidoreductase 0.274608
ZNF248 zinc finger protein 248 0.264872
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.256228
SV2C synaptic vesicle glycoprotein 2C 0.256228
ALPK1 alpha-kinase 1 0.256228
EML6 echinoderm microtubule associated protein like 6 0.256228
CMYA5 cardiomyopathy associated 5 0.256228
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.256228
STK33 serine/threonine kinase 33 0.256228
FAIM2 Fas apoptotic inhibitory molecule 2 0.197766
CAMK1G calcium/calmodulin-dependent protein kinase IG 0.197766
MAP1A microtubule-associated protein 1A 0.197766
SFRP2 secreted frizzled-related protein 2 0.197766
DARS aspartyl-tRNA synthetase 0.197766
CDH12 cadherin 12, type 2 (N-cadherin 2) 0.197766
EIF4E3 eukaryotic translation initiation factor 4E family member 3 0.15771
HOXB1 homeobox B1 0.15771
EXOC4 exocyst complex component 4 0.15771
ANO3 anoctamin 3 0.126165
PKP1 plakophilin 1 0.126165
COL21A1 collagen, type XXI, alpha 1 0.126165
APOC1 apolipoprotein C-I 0.126165
RARB retinoic acid receptor, beta 0.126165
ANKDD1B ankyrin repeat and death domain containing 1B 0.126165
MEX3B mex-3 RNA binding family member B 0.126165
LCT lactase 0.126165
FBN2 fibrillin 2 0.126165
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.126165
MDFIC MyoD family inhibitor domain containing 0.126165
MACROD2 MACRO domain containing 2 0.100789
DIRAS2 DIRAS family, GTP-binding RAS-like 2 0.100789
PFKP phosphofructokinase, platelet 0.100789
KDM4C lysine (K)-specific demethylase 4C 0.100789
OVCH2 ovochymase 2 (gene/pseudogene) 0.100789
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 0.100789
RGS6 regulator of G-protein signaling 6 0.100789
RFTN1 raftlin, lipid raft linker 1 0.100789
PALD1 phosphatase domain containing, paladin 1 0.100789
ARHGAP12 Rho GTPase activating protein 12 0.080593
MLN motilin 0.080593
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 0.080593
HDAC4 histone deacetylase 4 0.080593
THEMIS thymocyte selection associated 0.080593
FAT1 FAT atypical cadherin 1 0.064973
TRUB2 TruB pseudouridine (psi) synthase family member 2 0.064973
KCTD8 potassium channel tetramerization domain containing 8 0.064973
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.064973
LIPA lipase A, lysosomal acid, cholesterol esterase 0.064973
IFITM8P interferon induced transmembrane protein 8 pseudogene 0.064973
POC5 POC5 centriolar protein 0.052255
C9ORF84 chromosome 9 open reading frame 84 0.052255
INO80D INO80 complex subunit D 0.052255
CYB5R2 cytochrome b5 reductase 2 0.052255
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.052255
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 0.052255
NRXN1 neurexin 1 0.052255
C8ORF37 chromosome 8 open reading frame 37 0.043246
HOXB3 homeobox B3 0.043246
FAM83B family with sequence similarity 83, member B 0.043246