nucleic acid phosphodiester bond hydrolysis Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The nucleic acid metabolic process in which the phosphodiester bonds between nucleotides are cleaved by hydrolysis. (Gene Ontology, GO_0090305)
External Link http://amigo.geneontology.org/amigo/term/GO:0090305
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Genes

215 genes participating in the nucleic acid phosphodiester bond hydrolysis biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
AEN apoptosis enhancing nuclease
AGO1 argonaute RISC catalytic component 1
AGO2 argonaute RISC catalytic component 2
AGO3 argonaute RISC catalytic component 3
AGO4 argonaute RISC catalytic component 4
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
ANG angiogenin, ribonuclease, RNase A family, 5
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
APLF aprataxin and PNKP like factor
APTX aprataxin
ASTE1 asteroid homolog 1 (Drosophila)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BLM Bloom syndrome, RecQ helicase-like
BOP1 block of proliferation 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CECR2 cat eye syndrome chromosome region, candidate 2
CLP1 cleavage and polyadenylation factor I subunit 1
CNOT1 CCR4-NOT transcription complex, subunit 1
CNOT2 CCR4-NOT transcription complex, subunit 2
CNOT6 CCR4-NOT transcription complex, subunit 6
CNOT6L CCR4-NOT transcription complex, subunit 6-like
CNOT7 CCR4-NOT transcription complex, subunit 7
CNOT8 CCR4-NOT transcription complex, subunit 8
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CYCS cytochrome c, somatic
DBR1 debranching RNA lariats 1
DCLRE1A DNA cross-link repair 1A
DCLRE1B DNA cross-link repair 1B
DCLRE1C DNA cross-link repair 1C
DCP1B decapping mRNA 1B
DCP2 decapping mRNA 2
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DGCR8 DGCR8 microprocessor complex subunit
DICER1 dicer 1, ribonuclease type III
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DIS3L DIS3 like exosome 3'-5' exoribonuclease
DIS3L2 DIS3 like 3'-5' exoribonuclease 2
DNA2 DNA replication helicase/nuclease 2
DNASE1 deoxyribonuclease I
DNASE1L1 deoxyribonuclease I-like 1
DNASE1L2 deoxyribonuclease I-like 2
DNASE1L3 deoxyribonuclease I-like 3
DNASE2 deoxyribonuclease II, lysosomal
DNASE2B deoxyribonuclease II beta
DROSHA drosha, ribonuclease type III
DXO decapping exoribonuclease
ELAC1 elaC ribonuclease Z 1
ELAC2 elaC ribonuclease Z 2
EME1 essential meiotic structure-specific endonuclease 1
EME2 essential meiotic structure-specific endonuclease subunit 2
ENDOD1 endonuclease domain containing 1
ENDOG endonuclease G
ENDOU endonuclease, polyU-specific
ENDOV endonuclease V
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERCC3 excision repair cross-complementation group 3
ERCC4 excision repair cross-complementation group 4
ERCC5 excision repair cross-complementation group 5
ERI1 exoribonuclease 1
ERI2 ERI1 exoribonuclease family member 2
ERI3 ERI1 exoribonuclease family member 3
ERN1 endoplasmic reticulum to nucleus signaling 1
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD1 exonuclease 3'-5' domain containing 1
EXD2 exonuclease 3'-5' domain containing 2
EXD3 exonuclease 3'-5' domain containing 3
EXO1 exonuclease 1
EXO5 exonuclease 5
EXOG endo/exonuclease (5'-3'), endonuclease G-like
EXOSC10 exosome component 10
EXOSC2 exosome component 2
EXOSC3 exosome component 3
EXOSC4 exosome component 4
EXOSC5 exosome component 5
EXOSC7 exosome component 7
EXOSC9 exosome component 9
FAN1 FANCD2/FANCI-associated nuclease 1
FANCM Fanconi anemia, complementation group M
FBXO18 F-box protein, helicase, 18
FEN1 flap structure-specific endonuclease 1
FOXL2 forkhead box L2
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GEN1 GEN1 Holliday junction 5' flap endonuclease
H1F0 H1 histone family, member 0
HARBI1 harbinger transposase derived 1
HMGA2 high mobility group AT-hook 2
HMGB1 high mobility group box 1
HMGB2 high mobility group box 2
HORMAD1 HORMA domain containing 1
HRSP12 heat-responsive protein 12
ISG20 interferon stimulated exonuclease gene 20kDa
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
KPNA1 karyopherin alpha 1 (importin alpha 5)
KPNB1 karyopherin (importin) beta 1
LOC81691 exonuclease NEF-sp
MBD4 methyl-CpG binding domain protein 4
MEI4 meiosis-specific 4 homolog (S. cerevisiae)
MEIOB meiosis specific with OB domains
MGME1 mitochondrial genome maintenance exonuclease 1
MOV10 Mov10 RISC complex RNA helicase
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MRPL44 mitochondrial ribosomal protein L44
MUS81 MUS81 structure-specific endonuclease subunit
N4BP2 NEDD4 binding protein 2
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NEIL2 nei endonuclease VIII-like 2 (E. coli)
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NOL9 nucleolar protein 9
NOP14 NOP14 nucleolar protein
NTHL1 nth endonuclease III-like 1 (E. coli)
OGG1 8-oxoguanine DNA glycosylase
PAN2 PAN2 poly(A) specific ribonuclease subunit
PAN3 PAN3 poly(A) specific ribonuclease subunit
PARN poly(A)-specific ribonuclease
PCF11 PCF11 cleavage and polyadenylation factor subunit
PDE12 phosphodiesterase 12
PELO pelota homolog (Drosophila)
PGAP1 post-GPI attachment to proteins 1
PLD6 phospholipase D family, member 6
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PNKP polynucleotide kinase 3'-phosphatase
PNPT1 polyribonucleotide nucleotidyltransferase 1
PNRC2 proline-rich nuclear receptor coactivator 2
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLG polymerase (DNA directed), gamma
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
PPP1R8 protein phosphatase 1, regulatory subunit 8
PXDNL peroxidasin-like
RAD1 RAD1 checkpoint DNA exonuclease
RAD50 RAD50 homolog (S. cerevisiae)
RAD51C RAD51 paralog C
RAD52 RAD52 homolog (S. cerevisiae)
RAD9A RAD9 homolog A (S. pombe)
RAG1 recombination activating gene 1
RBBP8 retinoblastoma binding protein 8
RCL1 RNA terminal phosphate cyclase-like 1
REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae)
REXO2 RNA exonuclease 2
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae)
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNASE11 ribonuclease, RNase A family, 11 (non-active)
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNASE3 ribonuclease, RNase A family, 3
RNASE4 ribonuclease, RNase A family, 4
RNASE6 ribonuclease, RNase A family, k6
RNASE7 ribonuclease, RNase A family, 7
RNASE8 ribonuclease, RNase A family, 8
RNASEH1 ribonuclease H1
RNASEH2A ribonuclease H2, subunit A
RNASEH2B ribonuclease H2, subunit B
RNASEK ribonuclease, RNase K
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNASET2 ribonuclease T2
RPP21 ribonuclease P/MRP 21kDa subunit
RPP25 ribonuclease P/MRP 25kDa subunit
RPP30 ribonuclease P/MRP 30kDa subunit
RPP38 ribonuclease P/MRP 38kDa subunit
RPP40 ribonuclease P/MRP 40kDa subunit
RPS21 ribosomal protein S21
RPS3 ribosomal protein S3
RPSA ribosomal protein SA
SETMAR SET domain and mariner transposase fusion gene
SLX4 SLX4 structure-specific endonuclease subunit
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
SMG6 SMG6 nonsense mediated mRNA decay factor
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SND1 staphylococcal nuclease and tudor domain containing 1
SPO11 SPO11 meiotic protein covalently bound to DSB
STRA8 stimulated by retinoic acid 8
TATDN1 TatD DNase domain containing 1
TATDN2 TatD DNase domain containing 2
TATDN3 TatD DNase domain containing 3
TDP1 tyrosyl-DNA phosphodiesterase 1
TDP2 tyrosyl-DNA phosphodiesterase 2
TREX1 three prime repair exonuclease 1
TREX2 three prime repair exonuclease 2
TSEN15 TSEN15 tRNA splicing endonuclease subunit
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TSEN34 TSEN34 tRNA splicing endonuclease subunit
TSN translin
TSNAX translin-associated factor X
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBE2N ubiquitin-conjugating enzyme E2N
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2
USB1 U6 snRNA biogenesis 1
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
WDR33 WD repeat domain 33
WRN Werner syndrome, RecQ helicase-like
XPA xeroderma pigmentosum, complementation group A
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XRN1 5'-3' exoribonuclease 1
XRN2 5'-3' exoribonuclease 2
ZC3H12A zinc finger CCCH-type containing 12A
ZC3H12B zinc finger CCCH-type containing 12B
ZC3H12C zinc finger CCCH-type containing 12C
ZC3H12D zinc finger CCCH-type containing 12D
ZRANB3 zinc finger, RAN-binding domain containing 3