nuclear ubiquitin ligase complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A ubiquitin ligase complex found in the nucleus. (Gene Ontology, GO_0000152)
Similar Terms
Downloads & Tools

Genes

332 proteins co-occuring with the nuclear ubiquitin ligase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CDC20 cell division cycle 20 3.56263
PTTG1 pituitary tumor-transforming 1 2.49161
CDC27 cell division cycle 27 2.30578
FBXO5 F-box protein 5 2.25662
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 2.06413
PARK2 parkin RBR E3 ubiquitin protein ligase 1.93274
ANAPC11 anaphase promoting complex subunit 11 1.92856
CCNB1 cyclin B1 1.92647
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 1.90008
CDC16 cell division cycle 16 1.88763
ANAPC5 anaphase promoting complex subunit 5 1.84566
FBXO43 F-box protein 43 1.84497
CDC23 cell division cycle 23 1.83883
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 1.73498
CDK1 cyclin-dependent kinase 1 1.70816
BUB3 BUB3 mitotic checkpoint protein 1.70014
ANAPC10 anaphase promoting complex subunit 10 1.66357
PLK1 polo-like kinase 1 1.58679
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 1.57703
ANAPC4 anaphase promoting complex subunit 4 1.56674
SKP1 S-phase kinase-associated protein 1 1.56333
RNF4 ring finger protein 4 1.55537
UBE2S ubiquitin-conjugating enzyme E2S 1.53783
UBE2K ubiquitin-conjugating enzyme E2K 1.38405
BARD1 BRCA1 associated RING domain 1 1.36088
CDC14A cell division cycle 14A 1.30819
CUL1 cullin 1 1.29264
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 1.2889
UBE2H ubiquitin-conjugating enzyme E2H 1.25443
GMNN geminin, DNA replication inhibitor 1.24027
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 1.20447
UBE2D2 ubiquitin-conjugating enzyme E2D 2 1.18286
CDC26 cell division cycle 26 1.15467
ANAPC13 anaphase promoting complex subunit 13 1.10562
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 1.09391
WEE1 WEE1 G2 checkpoint kinase 1.0812
UBE2C ubiquitin-conjugating enzyme E2C 1.07765
CDK2 cyclin-dependent kinase 2 1.04431
USP44 ubiquitin specific peptidase 44 1.00645
AURKB aurora kinase B 0.966474
CUEDC2 CUE domain containing 2 0.961667
BRCA1 breast cancer 1, early onset 0.927483
UBE2E3 ubiquitin-conjugating enzyme E2E 3 0.88286
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 0.856176
ANAPC2 anaphase promoting complex subunit 2 0.855257
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.845614
CDC34 cell division cycle 34 0.836892
EVI5 ecotropic viral integration site 5 0.834138
UBE2W ubiquitin-conjugating enzyme E2W (putative) 0.830007
CDC6 cell division cycle 6 0.82863
ANAPC7 anaphase promoting complex subunit 7 0.818534
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.809817
ANAPC16 anaphase promoting complex subunit 16 0.800187
TRIM39-RPP21 TRIM39-RPP21 readthrough 0.785071
PLK2 polo-like kinase 2 0.778669
SGOL1 shugoshin-like 1 (S. pombe) 0.769539
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 0.755891
CENPE centromere protein E, 312kDa 0.738263
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative) 0.737813
TRIM39 tripartite motif containing 39 0.727941
SUMO3 small ubiquitin-like modifier 3 0.716791
USP37 ubiquitin specific peptidase 37 0.716346
UBE2E2 ubiquitin-conjugating enzyme E2E 2 0.712351
RNF111 ring finger protein 111 0.707924
CDC25C cell division cycle 25C 0.701744
UBE2E1 ubiquitin-conjugating enzyme E2E 1 0.700423
SUMO2 small ubiquitin-like modifier 2 0.698223
UBE2A ubiquitin-conjugating enzyme E2A 0.696026
CDCA5 cell division cycle associated 5 0.692955
UBE2I ubiquitin-conjugating enzyme E2I 0.690764
RAE1 ribonucleic acid export 1 0.656033
UBE2T ubiquitin-conjugating enzyme E2T 0.652159
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) 0.638005
UIMC1 ubiquitin interaction motif containing 1 0.635013
RNF31 ring finger protein 31 0.632024
UBE2L3 ubiquitin-conjugating enzyme E2L 3 0.619255
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.610778
CKAP2L cytoskeleton associated protein 2-like 0.603596
CDT1 chromatin licensing and DNA replication factor 1 0.597276
CASC1 cancer susceptibility candidate 1 0.596855
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.590973
FBXO4 F-box protein 4 0.586361
RNF165 ring finger protein 165 0.580086
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 0.579669
CDCA3 cell division cycle associated 3 0.570496
FBXW8 F-box and WD repeat domain containing 8 0.567585
CCAR1 cell division cycle and apoptosis regulator 1 0.564262
UBE2N ubiquitin-conjugating enzyme E2N 0.559285
MAD2L1BP MAD2L1 binding protein 0.557214
FBXL14 F-box and leucine-rich repeat protein 14 0.552664
TP53 tumor protein p53 0.551012
TRIP13 thyroid hormone receptor interactor 13 0.542352
NUP98 nucleoporin 98kDa 0.532898
RAD18 RAD18 E3 ubiquitin protein ligase 0.529208
MDC1 mediator of DNA-damage checkpoint 1 0.529208
C18ORF25 chromosome 18 open reading frame 25 0.520206
ANAPC1 anaphase promoting complex subunit 1 0.508383
TMEM189 transmembrane protein 189 0.50757
UBE3A ubiquitin protein ligase E3A 0.499042
UBA1 ubiquitin-like modifier activating enzyme 1 0.4958
TK1 thymidine kinase 1, soluble 0.47442
KLHL3 kelch-like family member 3 0.473215
SPRTN SprT-like N-terminal domain 0.470005
CCNA2 cyclin A2 0.469604
MIIP migration and invasion inhibitory protein 0.4676
SPATC1 spermatogenesis and centriole associated 1 0.458404
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 0.456809
TRIM69 tripartite motif containing 69 0.447656
HOXC10 homeobox C10 0.446465
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.433801
CHEK1 checkpoint kinase 1 0.432618
UBE2G2 ubiquitin-conjugating enzyme E2G 2 0.429072
TPR translocated promoter region, nuclear basket protein 0.428678
TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 0.426711
FAM64A family with sequence similarity 64, member A 0.426318
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.419644
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.41221
FBXL5 F-box and leucine-rich repeat protein 5 0.409869
CDC25A cell division cycle 25A 0.399363
MASTL microtubule associated serine/threonine kinase-like 0.398975
CCNE1 cyclin E1 0.397811
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.39626
UBE3C ubiquitin protein ligase E3C 0.390068
NKX6-1 NK6 homeobox 1 0.389682
GRWD1 glutamate-rich WD repeat containing 1 0.385822
AURKA aurora kinase A 0.380814
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) 0.372366
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 0.370833
KIF18A kinesin family member 18A 0.368536
USP39 ubiquitin specific peptidase 39 0.367006
MIS12 MIS12 kinetochore complex component 0.363949
FBXW5 F-box and WD repeat domain containing 5 0.363567
COPS3 COP9 signalosome subunit 3 0.357086
RAD21 RAD21 homolog (S. pombe) 0.351762
CDC25B cell division cycle 25B 0.344178
PLCZ1 phospholipase C, zeta 1 0.341151
DTYMK deoxythymidylate kinase (thymidylate kinase) 0.338128
MOAP1 modulator of apoptosis 1 0.33511
BIRC6 baculoviral IAP repeat containing 6 0.333979
MPEG1 macrophage expressed 1 0.333225
BRSK2 BR serine/threonine kinase 2 0.331719
DBF4 DBF4 zinc finger 0.330213
MAK male germ cell-associated kinase 0.327581
TRIM25 tripartite motif containing 25 0.326829
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 0.326453
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase 0.323075
WEE2 WEE1 homolog 2 (S. pombe) 0.320077
PRCC papillary renal cell carcinoma (translocation-associated) 0.319702
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 0.318953
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.305515
E2F7 E2F transcription factor 7 0.298826
TUBGCP3 tubulin, gamma complex associated protein 3 0.292157
ZC3HC1 zinc finger, C3HC-type containing 1 0.287721
INVS inversin 0.286245
PDCD2 programmed cell death 2 0.285507
EPT1 ethanolaminephosphotransferase 1 0.285138
AURKAIP1 aurora kinase A interacting protein 1 0.267871
KIFC1 kinesin family member C1 0.266774
CKAP2 cytoskeleton associated protein 2 0.262755
CDC5L cell division cycle 5-like 0.260931
NEUROD2 neuronal differentiation 2 0.257652
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 0.251839
MCPH1 microcephalin 1 0.250751
PHF8 PHD finger protein 8 0.249302
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 0.244601
HOXD10 homeobox D10 0.239557
FAN1 FANCD2/FANCI-associated nuclease 1 0.237042
METTL13 methyltransferase like 13 0.235966
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.233459
UBD ubiquitin D 0.233101
GLS glutaminase 0.232744
HELZ helicase with zinc finger 0.232744
FLI1 Fli-1 proto-oncogene, ETS transcription factor 0.225622
RNF6 ring finger protein (C3H2C3 type) 6 0.223143
PPP1R10 protein phosphatase 1, regulatory subunit 10 0.222436
IL17RC interleukin 17 receptor C 0.222436
LUZP6 leucine zipper protein 6 0.218563
SSU72 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) 0.21716
CLTA clathrin, light chain A 0.215412
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.214017
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 0.211587
GTSE1 G-2 and S-phase expressed 1 0.21124
CCNB2 cyclin B2 0.210894
SMC3 structural maintenance of chromosomes 3 0.210203
RNF123 ring finger protein 123 0.207108
TRRAP transformation/transcription domain-associated protein 0.204718
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.202009
TACC3 transforming, acidic coiled-coil containing protein 3 0.202009
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.199325
ATM ATM serine/threonine kinase 0.198325
H2AFX H2A histone family, member X 0.197662
SENP6 SUMO1/sentrin specific peptidase 6 0.19733
NINL ninein-like 0.19601
PCNA proliferating cell nuclear antigen 0.19307
FOXG1 forkhead box G1 0.1921
SPOP speckle-type POZ protein 0.191777
ATR ATR serine/threonine kinase 0.191456
MCM2 minichromosome maintenance complex component 2 0.188905
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 0.18516
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 0.182122
SMAD3 SMAD family member 3 0.180634
CENPA centromere protein A 0.179167
NPHP3 nephronophthisis 3 (adolescent) 0.177439
SLC39A2 solute carrier family 39 (zinc transporter), member 2 0.173273
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 0.172201
KIF4A kinesin family member 4A 0.171149
SKA3 spindle and kinetochore associated complex subunit 3 0.168598
MAST4 microtubule associated serine/threonine kinase family member 4 0.168349
MCM7 minichromosome maintenance complex component 7 0.167125
CYCS cytochrome c, somatic 0.161905
ZW10 zw10 kinetochore protein 0.161275
NDC80 NDC80 kinetochore complex component 0.160254
BRD7 bromodomain containing 7 0.158882
LINGO1 leucine rich repeat and Ig domain containing 1 0.158315
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.157397
CBX4 chromobox homolog 4 0.144725
PRC1 protein regulator of cytokinesis 1 0.143573
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 0.140996
BMI1 BMI1 proto-oncogene, polycomb ring finger 0.1405
CBX7 chromobox homolog 7 0.139571
CBX8 chromobox homolog 8 0.138296
CBX2 chromobox homolog 2 0.137253
SCML2 sex comb on midleg-like 2 (Drosophila) 0.137192
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.137095
RNF2 ring finger protein 2 0.136919
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.136907
RING1 ring finger protein 1 0.136819
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.136302
KDM2B lysine (K)-specific demethylase 2B 0.136289
ASXL1 additional sex combs like transcriptional regulator 1 0.136236
HIST1H2AD histone cluster 1, H2ad 0.136096
HIST1H2AJ histone cluster 1, H2aj 0.136096
HIST1H2AM histone cluster 1, H2am 0.136096
H2AFJ H2A histone family, member J 0.136096
HIST1H2AH histone cluster 1, H2ah 0.136092
HIST1H2AG histone cluster 1, H2ag 0.136078
H2AFY2 H2A histone family, member Y2 0.13606
HIST1H2AE histone cluster 1, H2ae 0.136051
HIST1H2AB histone cluster 1, H2ab 0.136051
H2AFV H2A histone family, member V 0.136046
H2AFB1 H2A histone family, member B1 0.136015
H2AFB2 H2A histone family, member B2 0.135973
H2AFY H2A histone family, member Y 0.135932
PCGF2 polycomb group ring finger 2 0.135904
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 0.13583
L3MBTL2 l(3)mbt-like 2 (Drosophila) 0.135266
CBX6 chromobox homolog 6 0.1349
STC1 stanniocalcin 1 0.134225
HIST2H2AC histone cluster 2, H2ac 0.133366
HIST2H2AA4 histone cluster 2, H2aa4 0.13336
HIST2H2AA3 histone cluster 2, H2aa3 0.13336
RYBP RING1 and YY1 binding protein 0.132418
PCGF1 polycomb group ring finger 1 0.131742
MTF2 metal response element binding transcription factor 2 0.131469
E2F6 E2F transcription factor 6 0.131348
MUS81 MUS81 structure-specific endonuclease subunit 0.130106
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 0.129707
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 0.129523
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.129405
H3F3B H3 histone, family 3B (H3.3B) 0.129328
H3F3A H3 histone, family 3A 0.129328
SUZ12 SUZ12 polycomb repressive complex 2 subunit 0.129059
PCGF6 polycomb group ring finger 6 0.128837
KIF20B kinesin family member 20B 0.128455
PHC1 polyhomeotic homolog 1 (Drosophila) 0.128446
TDP1 tyrosyl-DNA phosphodiesterase 1 0.128418
CCNA1 cyclin A1 0.128316
YAF2 YY1 associated factor 2 0.128194
PIAS2 protein inhibitor of activated STAT, 2 0.12806
NMRAL1 NmrA-like family domain containing 1 0.127652
CDKN2A cyclin-dependent kinase inhibitor 2A 0.127431
PHC3 polyhomeotic homolog 3 (Drosophila) 0.126989
ZFP42 ZFP42 zinc finger protein 0.12683
PIAS4 protein inhibitor of activated STAT, 4 0.126518
PHC2 polyhomeotic homolog 2 (Drosophila) 0.126409
USP11 ubiquitin specific peptidase 11 0.126063
DOT1L DOT1-like histone H3K79 methyltransferase 0.125902
SENP1 SUMO1/sentrin specific peptidase 1 0.125868
EPN1 epsin 1 0.125741
CENPH centromere protein H 0.125577
PRMT8 protein arginine methyltransferase 8 0.125565
PIAS1 protein inhibitor of activated STAT, 1 0.12541
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 0.124847
RAD52 RAD52 homolog (S. cerevisiae) 0.124543
HSPA1B heat shock 70kDa protein 1B 0.123857
RUVBL2 RuvB-like AAA ATPase 2 0.123788
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 0.123747
BRCA2 breast cancer 2, early onset 0.12323
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.122884
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.122648
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.122498
PHF19 PHD finger protein 19 0.122483
EED embryonic ectoderm development 0.122453
ISG15 ISG15 ubiquitin-like modifier 0.121991
MOV10 Mov10 RISC complex RNA helicase 0.121464
RNF8 ring finger protein 8, E3 ubiquitin protein ligase 0.120899
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.120451
SFMBT1 Scm-like with four mbt domains 1 0.120115
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) 0.118961
HSPA1A heat shock 70kDa protein 1A 0.11851
BCOR BCL6 corepressor 0.116654
ASCL2 achaete-scute family bHLH transcription factor 2 0.116587
XPC xeroderma pigmentosum, complementation group C 0.116065
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.115808
TWIST1 twist family bHLH transcription factor 1 0.11543
HOXC13 homeobox C13 0.115142
AXIN1 axin 1 0.112214
CLIP1 CAP-GLY domain containing linker protein 1 0.11153
NANOG Nanog homeobox 0.110402
JARID2 jumonji, AT rich interactive domain 2 0.110217
STRA8 stimulated by retinoic acid 8 0.10947
EGLN2 egl-9 family hypoxia-inducible factor 2 0.109376
SETD7 SET domain containing (lysine methyltransferase) 7 0.109186
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.108798
KDM6A lysine (K)-specific demethylase 6A 0.108108
RAG1 recombination activating gene 1 0.107738
KLF4 Kruppel-like factor 4 (gut) 0.106354
CHAF1A chromatin assembly factor 1, subunit A (p150) 0.105418
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 0.105418
YY1 YY1 transcription factor 0.105272
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 0.104186
HDAC7 histone deacetylase 7 0.10392
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.103766
MNX1 motor neuron and pancreas homeobox 1 0.102986
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 0.101741
PRMT2 protein arginine methyltransferase 2 0.101247
KMT2B lysine (K)-specific methyltransferase 2B 0.100915
UBE2B ubiquitin-conjugating enzyme E2B 0.100072
PML promyelocytic leukemia 0.099685
CUL7 cullin 7 0.099425
EYA1 EYA transcriptional coactivator and phosphatase 1 0.098814
NEK2 NIMA-related kinase 2 0.098814