nuclear transcriptional repressor complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription. (Gene Ontology, GO_0090568)
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Genes

228 proteins co-occuring with the nuclear transcriptional repressor complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
HDAC1 histone deacetylase 1 0.345882
HDAC9 histone deacetylase 9 0.291294
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.162188
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.162188
SIN3A SIN3 transcription regulator family member A 0.149886
HDAC2 histone deacetylase 2 0.147717
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 0.14539
CHD4 chromodomain helicase DNA binding protein 4 0.144785
MTA1 metastasis associated 1 0.143824
MXI1 MAX interactor 1, dimerization protein 0.143794
MTA2 metastasis associated 1 family, member 2 0.142912
MXD4 MAX dimerization protein 4 0.141725
MTA3 metastasis associated 1 family, member 3 0.141622
GTF2B general transcription factor IIB 0.14145
TAF1L TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like 0.141149
NCOR1 nuclear receptor corepressor 1 0.140799
ZFPM1 zinc finger protein, FOG family member 1 0.14032
RBBP4 retinoblastoma binding protein 4 0.140235
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) 0.140217
MXD1 MAX dimerization protein 1 0.139744
CHD3 chromodomain helicase DNA binding protein 3 0.139372
MAX MYC associated factor X 0.139233
GATAD2B GATA zinc finger domain containing 2B 0.139222
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 0.139069
GATAD2A GATA zinc finger domain containing 2A 0.138324
MED7 mediator complex subunit 7 0.138049
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.137903
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 0.137751
MBD3L1 methyl-CpG binding domain protein 3-like 1 0.137742
MED10 mediator complex subunit 10 0.137658
RCOR1 REST corepressor 1 0.137609
MBD3 methyl-CpG binding domain protein 3 0.137406
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.13646
EDN3 endothelin 3 0.13644
HIC1 hypermethylated in cancer 1 0.136399
MBD3L2 methyl-CpG binding domain protein 3-like 2 0.136394
SALL1 spalt-like transcription factor 1 0.13625
SETDB1 SET domain, bifurcated 1 0.136234
KDM1A lysine (K)-specific demethylase 1A 0.136208
PCCA propionyl CoA carboxylase, alpha polypeptide 0.136135
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 0.136024
MNT MAX network transcriptional repressor 0.136018
CFAP20 cilia and flagella associated protein 20 0.135639
IPO13 importin 13 0.134785
ZNF521 zinc finger protein 521 0.134553
ZFHX4 zinc finger homeobox 4 0.134553
EBF1 early B-cell factor 1 0.133678
TBP TATA box binding protein 0.133557
RBBP7 retinoblastoma binding protein 7 0.13324
ZGPAT zinc finger, CCCH-type with G patch domain 0.13312
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.132978
ZNF827 zinc finger protein 827 0.132978
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 0.132963
H3F3A H3 histone, family 3A 0.132913
H3F3B H3 histone, family 3B (H3.3B) 0.132913
PHF6 PHD finger protein 6 0.131674
ZFPM2 zinc finger protein, FOG family member 2 0.131535
SKI SKI proto-oncogene 0.131494
FAM64A family with sequence similarity 64, member A 0.131386
GFI1B growth factor independent 1B transcription repressor 0.131361
RB1 retinoblastoma 1 0.131227
FOXK1 forkhead box K1 0.130978
MBD2 methyl-CpG binding domain protein 2 0.130874
NANOG Nanog homeobox 0.130681
KNG1 kininogen 1 0.130592
BCOR BCL6 corepressor 0.130547
PIAS1 protein inhibitor of activated STAT, 1 0.130228
TRIM27 tripartite motif containing 27 0.130163
GIGYF2 GRB10 interacting GYF protein 2 0.130145
CCL14 chemokine (C-C motif) ligand 14 0.130061
CARM1 coactivator-associated arginine methyltransferase 1 0.129957
KLF1 Kruppel-like factor 1 (erythroid) 0.129814
FOXP4 forkhead box P4 0.129766
HDAC3 histone deacetylase 3 0.129757
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 0.129345
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa 0.129245
PRMT5 protein arginine methyltransferase 5 0.129214
FOXK2 forkhead box K2 0.129103
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.129062
FOXP1 forkhead box P1 0.12898
PIAS2 protein inhibitor of activated STAT, 2 0.128613
ACTL6A actin-like 6A 0.128431
E2F7 E2F transcription factor 7 0.128201
TBX18 T-box 18 0.128201
CCND2 cyclin D2 0.128157
EOMES eomesodermin 0.128091
MYB v-myb avian myeloblastosis viral oncogene homolog 0.128024
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.127832
EGLN2 egl-9 family hypoxia-inducible factor 2 0.127797
TBX20 T-box 20 0.127786
DNAH8 dynein, axonemal, heavy chain 8 0.127774
ESR1 estrogen receptor 1 0.127497
MCM8 minichromosome maintenance complex component 8 0.12726
ATOH1 atonal homolog 1 (Drosophila) 0.127212
L3MBTL2 l(3)mbt-like 2 (Drosophila) 0.127212
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 0.127176
SALL4 spalt-like transcription factor 4 0.127128
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) 0.127018
ATN1 atrophin 1 0.127006
PIAS3 protein inhibitor of activated STAT, 3 0.126933
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.126697
TRIM28 tripartite motif containing 28 0.126659
LECT2 leukocyte cell-derived chemotaxin 2 0.126302
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.126184
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.12596
MECP2 methyl CpG binding protein 2 0.12596
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 0.12596
PRMT7 protein arginine methyltransferase 7 0.125946
ZNF217 zinc finger protein 217 0.125772
LMO2 LIM domain only 2 (rhombotin-like 1) 0.125622
TRIM24 tripartite motif containing 24 0.125414
ZNF423 zinc finger protein 423 0.125302
HIST2H2AC histone cluster 2, H2ac 0.125274
HIST2H2AA3 histone cluster 2, H2aa3 0.12526
HIST2H2AA4 histone cluster 2, H2aa4 0.12526
EGR2 early growth response 2 0.125203
SAE1 SUMO1 activating enzyme subunit 1 0.125146
TP53 tumor protein p53 0.125075
ARID1A AT rich interactive domain 1A (SWI-like) 0.124988
PHF21A PHD finger protein 21A 0.124945
EGR1 early growth response 1 0.124872
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 0.124769
PRC1 protein regulator of cytokinesis 1 0.124725
PHF19 PHD finger protein 19 0.124562
RPL26L1 ribosomal protein L26-like 1 0.124547
ELF5 E74-like factor 5 (ets domain transcription factor) 0.124136
TET1 tet methylcytosine dioxygenase 1 0.124074
KDM3A lysine (K)-specific demethylase 3A 0.124027
RNF8 ring finger protein 8, E3 ubiquitin protein ligase 0.123631
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 0.123517
MECOM MDS1 and EVI1 complex locus 0.123254
TAL1 T-cell acute lymphocytic leukemia 1 0.123138
MYCBP MYC binding protein 0.122969
KLF10 Kruppel-like factor 10 0.122816
GBX2 gastrulation brain homeobox 2 0.12245
DICER1 dicer 1, ribonuclease type III 0.12229
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) 0.122219
CTBP1 C-terminal binding protein 1 0.122074
SETD1B SET domain containing 1B 0.12178
CDX2 caudal type homeobox 2 0.121762
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.121632
BCL6 B-cell CLL/lymphoma 6 0.121613
WDR77 WD repeat domain 77 0.121328
ZBTB7A zinc finger and BTB domain containing 7A 0.121251
SAP18 Sin3A-associated protein, 18kDa 0.121232
VPRBP Vpr (HIV-1) binding protein 0.121115
KDM5B lysine (K)-specific demethylase 5B 0.120919
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 0.12076
SIN3B SIN3 transcription regulator family member B 0.120376
HNMT histamine N-methyltransferase 0.119917
HIST1H4A histone cluster 1, H4a 0.119725
HIST1H4E histone cluster 1, H4e 0.119725
HIST1H4D histone cluster 1, H4d 0.119725
HIST1H4B histone cluster 1, H4b 0.119725
HIST1H4K histone cluster 1, H4k 0.119725
HIST2H4B histone cluster 2, H4b 0.119725
HIST1H4J histone cluster 1, H4j 0.119725
HIST1H4C histone cluster 1, H4c 0.119725
HIST1H4I histone cluster 1, H4i 0.119725
HIST1H4H histone cluster 1, H4h 0.119725
HIST1H4F histone cluster 1, H4f 0.119704
HIST4H4 histone cluster 4, H4 0.119704
HIST2H4A histone cluster 2, H4a 0.119704
HIST1H4L histone cluster 1, H4l 0.119704
HDAC5 histone deacetylase 5 0.119596
RUVBL1 RuvB-like AAA ATPase 1 0.11953
SAP30 Sin3A-associated protein, 30kDa 0.119509
ZNF222 zinc finger protein 222 0.119465
MYO5A myosin VA (heavy chain 12, myoxin) 0.119378
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.119356
KDM5A lysine (K)-specific demethylase 5A 0.118977
MCRS1 microspherule protein 1 0.11891
CIDEB cell death-inducing DFFA-like effector b 0.118841
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.118773
RPL26 ribosomal protein L26 0.11875
HBG2 hemoglobin, gamma G 0.118727
TRIM10 tripartite motif containing 10 0.118658
ARID1B AT rich interactive domain 1B (SWI1-like) 0.118543
TRIM26 tripartite motif containing 26 0.118332
PAX5 paired box 5 0.11812
AKR1C4 aldo-keto reductase family 1, member C4 0.11812
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.118096
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 0.117685
TRIM15 tripartite motif containing 15 0.117685
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.117537
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.117488
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.117438
BAZ2A bromodomain adjacent to zinc finger domain, 2A 0.117364
TTF1 transcription termination factor, RNA polymerase I 0.117264
GATA2 GATA binding protein 2 0.116805
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.116414
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.115933
UBA2 ubiquitin-like modifier activating enzyme 2 0.115905
HTT huntingtin 0.115878
HARS histidyl-tRNA synthetase 0.115824
SETD1A SET domain containing 1A 0.115242
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.114929
HMGB1 high mobility group box 1 0.1147
HDAC4 histone deacetylase 4 0.114465
FOXH1 forkhead box H1 0.114436
SIX2 SIX homeobox 2 0.11423
RAD21 RAD21 homolog (S. pombe) 0.11411
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.11402
LDB1 LIM domain binding 1 0.113809
XPO1 exportin 1 0.113503
MAT2A methionine adenosyltransferase II, alpha 0.113067
RNF2 ring finger protein 2 0.113004
KAT7 K(lysine) acetyltransferase 7 0.112877
TIPIN TIMELESS interacting protein 0.111602
MORF4 mortality factor 4 (pseudogene) 0.111227
EGLN3 egl-9 family hypoxia-inducible factor 3 0.111227
NPPA natriuretic peptide A 0.111159
RSPO1 R-spondin 1 0.110638
TOP1 topoisomerase (DNA) I 0.110105
EHMT1 euchromatic histone-lysine N-methyltransferase 1 0.109376
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 0.109339
TDG thymine-DNA glycosylase 0.109003
CHD1L chromodomain helicase DNA binding protein 1-like 0.108549
TCF12 transcription factor 12 0.107654
CCL2 chemokine (C-C motif) ligand 2 0.107456
EWSR1 EWS RNA-binding protein 1 0.107338
THBS4 thrombospondin 4 0.107338
EGR3 early growth response 3 0.106893
PAX2 paired box 2 0.106771
WIPF2 WAS/WASL interacting protein family, member 2 0.106401
PLAUR plasminogen activator, urokinase receptor 0.106236
PELP1 proline, glutamate and leucine rich protein 1 0.105733
SENP1 SUMO1/sentrin specific peptidase 1 0.105733