nuclear scf ubiquitin ligase complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A ubiquitin ligase complex, located in the nucleus, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1). (Gene Ontology, GO_0043224)
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5 proteins co-occuring with the nuclear scf ubiquitin ligase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
ZC3HC1 zinc finger, C3HC-type containing 1 1.76432
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.882399
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.718125
CCNB1 cyclin B1 0.614589
CDK1 cyclin-dependent kinase 1 0.520206