nuclear replisome Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A multi-component enzymatic machine at the nuclear replication fork, which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins. (Gene Ontology, GO_0043601)
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Genes

18 proteins localized to the nuclear replisome cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CHRAC1 chromatin accessibility complex 1 0.663342
POLD3 polymerase (DNA-directed), delta 3, accessory subunit 0.663342
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.663342
POLE4 polymerase (DNA-directed), epsilon 4, accessory subunit 0.663342
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.663342
POLE polymerase (DNA directed), epsilon, catalytic subunit 0.663342
RPA4 replication protein A4, 30kDa 0.663342
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit 0.663342
RPA2 replication protein A2, 32kDa 0.663342
RPA3 replication protein A3, 14kDa 0.663342
RPA1 replication protein A1, 70kDa 0.663342
PURB purine-rich element binding protein B 0.237908
PURA purine-rich element binding protein A 0.237908
MCM3 minichromosome maintenance complex component 3 0.237908
POLA2 polymerase (DNA directed), alpha 2, accessory subunit 0.098109
KIAA2022 KIAA2022 0.098109
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 0.098109
POLD2 polymerase (DNA directed), delta 2, accessory subunit 0.03318