nuclear pore outer ring Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A subcomplex of the nuclear pore complex (NPC) that forms the outer rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two outer rings each contain multiple copies of the following proteins: Nup133p, Nup120p, Nup145Cp, Nup85p, Nup84p, Seh1p, and Sec13p. In vertebrates, the two outer rings each contain multiple copies of the following proteins: Nup133, Nup160, Nup96, Nup75, Nup107, Seh1, Sec13, Nup43, Nup37, and ALADIN. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup84 complex (S. cerevisiae) or the Nup107-160 complex (vertebrates). (Gene Ontology, GO_0031080)
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Genes

39 proteins co-occuring with the nuclear pore outer ring cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
NUP107 nucleoporin 107kDa 2.24589
SEH1L SEH1-like (S. cerevisiae) 2.094
AHCTF1 AT hook containing transcription factor 1 1.98835
NUP85 nucleoporin 85kDa 1.95372
NUP133 nucleoporin 133kDa 1.83474
NUP43 nucleoporin 43kDa 1.71125
NUP37 nucleoporin 37kDa 1.3532
NUP160 nucleoporin 160kDa 1.27664
CTDNEP1 CTD nuclear envelope phosphatase 1 1.05136
SARNP SAP domain containing ribonucleoprotein 0.878712
WRNIP1 Werner helicase interacting protein 1 0.744574
NXF1 nuclear RNA export factor 1 0.737363
SEC13 SEC13 homolog (S. cerevisiae) 0.734666
NMD3 NMD3 ribosome export adaptor 0.696905
NUP93 nucleoporin 93kDa 0.687264
RTN1 reticulon 1 0.684207
NXT1 nuclear transport factor 2-like export factor 1 0.680719
EML1 echinoderm microtubule associated protein like 1 0.668559
SENP1 SUMO1/sentrin specific peptidase 1 0.596014
TREX2 three prime repair exonuclease 2 0.592652
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.558042
CETN2 centrin, EF-hand protein, 2 0.520615
SUN1 Sad1 and UNC84 domain containing 1 0.488519
RANGAP1 Ran GTPase activating protein 1 0.478843
RGPD3 RANBP2-like and GRIP domain containing 3 0.457606
SUMO1 small ubiquitin-like modifier 1 0.443292
CENPF centromere protein F, 350/400kDa 0.439333
NDC1 NDC1 transmembrane nucleoporin 0.40714
NUTF2 nuclear transport factor 2 0.385436
BUB3 BUB3 mitotic checkpoint protein 0.372366
RANBP2 RAN binding protein 2 0.363949
NUP98 nucleoporin 98kDa 0.332095
WRN Werner syndrome, RecQ helicase-like 0.310358
RAN RAN, member RAS oncogene family 0.305515
CENPE centromere protein E, 312kDa 0.288091
ATR ATR serine/threonine kinase 0.220321
KIAA0101 KIAA0101 0.209169
MCM2 minichromosome maintenance complex component 2 0.184547
MCM7 minichromosome maintenance complex component 7 0.163865