nuclear pore central transport channel Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The central substructure of the nuclear pore complex (NPC), through which nucleocytoplasmic transport of RNAs, proteins and small molecules occurs. The central transport channel is filled with FG-nucleoporins, which form a selective barrier and provide a series of binding sites for transporter proteins. Characterized S. cerevisiae FG-nucleoporins include Nup159p, Nup145Np, Nup116p, Nup100p, Nsp1p, Nup57p, Nup49p, Nup42p, Nup53p, Nup59p/Asm4p, Nup60p and Nup1. Characterized vertebrate FG-nucleoporins include Nup214, Nup98, Nup62, Nup54, Nup58/45, NLP1, and Nup153. (Gene Ontology, GO_0044613)
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7 proteins co-occuring with the nuclear pore central transport channel cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
TREX2 three prime repair exonuclease 2 1.13574
GLE1 GLE1 RNA export mediator 1.00596
NUP214 nucleoporin 214kDa 0.892093
TRAF3 TNF receptor-associated factor 3 0.842401
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.516532
STAT1 signal transducer and activator of transcription 1, 91kDa 0.454816
CD40 CD40 molecule, TNF receptor superfamily member 5 0.414946