nuclear lamina Gene Set

Dataset GO Cellular Component Annotations
Category structural or functional annotations
Type cellular component
Description The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a cell nucleus, composed of lamin filaments. The polypeptides of the lamina are thought to be concerned in the dissolution of the nuclear envelope and its re-formation during mitosis. The lamina is composed of lamin A and lamin C filaments cross-linked into an orthogonal lattice, which is attached via lamin B to the inner nuclear membrane through interactions with a lamin B receptor, an IFAP, in the membrane. (Gene Ontology, GO_0005652)
External Link http://amigo.geneontology.org/amigo/term/GO:0005652
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Genes

4 proteins localized to the nuclear lamina cellular component from the curated GO Cellular Component Annotations dataset.

Symbol Name
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
NARF nuclear prelamin A recognition factor
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)