nuclear envelope Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space). (Gene Ontology, GO_0005635)
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Genes

293 proteins localized to the nuclear envelope cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
NUP85 nucleoporin 85kDa 0.663342
NUP50 nucleoporin 50kDa 0.663342
TMPO thymopoietin 0.663342
NUP43 nucleoporin 43kDa 0.663342
TBC1D20 TBC1 domain family, member 20 0.663342
RTN4 reticulon 4 0.663342
WDFY3 WD repeat and FYVE domain containing 3 0.663342
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.663342
SUN2 Sad1 and UNC84 domain containing 2 0.663342
SUN1 Sad1 and UNC84 domain containing 1 0.663342
GPER1 G protein-coupled estrogen receptor 1 0.663342
CTDNEP1 CTD nuclear envelope phosphatase 1 0.663342
WTAP Wilms tumor 1 associated protein 0.663342
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.663342
EPC1 enhancer of polycomb homolog 1 (Drosophila) 0.663342
NUP88 nucleoporin 88kDa 0.663342
AQP1 aquaporin 1 (Colton blood group) 0.663342
TRIM27 tripartite motif containing 27 0.663342
NDC1 NDC1 transmembrane nucleoporin 0.663342
PRICKLE1 prickle homolog 1 (Drosophila) 0.663342
LTC4S leukotriene C4 synthase 0.663342
AKAP6 A kinase (PRKA) anchor protein 6 0.663342
LMNB2 lamin B2 0.663342
LMNB1 lamin B1 0.663342
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.663342
SIGMAR1 sigma non-opioid intracellular receptor 1 0.663342
MVP major vault protein 0.663342
RBM15 RNA binding motif protein 15 0.663342
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) 0.663342
TREX1 three prime repair exonuclease 1 0.663342
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.663342
EGFR epidermal growth factor receptor 0.663342
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.663342
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 0.663342
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1 0.663342
ATP11B ATPase, class VI, type 11B 0.663342
PARP1 poly (ADP-ribose) polymerase 1 0.663342
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.663342
TPR translocated promoter region, nuclear basket protein 0.663342
LBR lamin B receptor 0.663342
SIRT1 sirtuin 1 0.663342
COTL1 coactosin-like F-actin binding protein 1 0.663342
CENPF centromere protein F, 350/400kDa 0.663342
ATRAID all-trans retinoic acid-induced differentiation factor 0.663342
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2 0.663342
MYO1C myosin IC 0.663342
TOR1B torsin family 1, member B (torsin B) 0.663342
LEMD3 LEM domain containing 3 0.663342
LEMD2 LEM domain containing 2 0.663342
S100A6 S100 calcium binding protein A6 0.663342
RGPD8 RANBP2-like and GRIP domain containing 8 0.663342
MX2 MX dynamin-like GTPase 2 0.663342
DNASE1 deoxyribonuclease I 0.663342
PARP16 poly (ADP-ribose) polymerase family, member 16 0.663342
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.663342
ATP1B4 ATPase, Na+/K+ transporting, beta 4 polypeptide 0.663342
XPO7 exportin 7 0.663342
LRRC59 leucine rich repeat containing 59 0.663342
NUP133 nucleoporin 133kDa 0.663342
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 0.663342
ADRA1A adrenoceptor alpha 1A 0.663342
ADRA1B adrenoceptor alpha 1B 0.663342
NELL1 NEL-like 1 (chicken) 0.663342
RNF43 ring finger protein 43 0.663342
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 0.663342
PML promyelocytic leukemia 0.663342
TNMD tenomodulin 0.663342
GLE1 GLE1 RNA export mediator 0.663342
PSEN2 presenilin 2 0.663342
PSEN1 presenilin 1 0.663342
RANBP17 RAN binding protein 17 0.663342
LRPPRC leucine-rich pentatricopeptide repeat containing 0.663342
EIF5A eukaryotic translation initiation factor 5A 0.663342
MTA1 metastasis associated 1 0.663342
LMNA lamin A/C 0.663342
AAAS achalasia, adrenocortical insufficiency, alacrimia 0.663342
ALOX5 arachidonate 5-lipoxygenase 0.663342
RAN RAN, member RAS oncogene family 0.663342
TOR1AIP2 torsin A interacting protein 2 0.663342
MRPL19 mitochondrial ribosomal protein L19 0.663342
DHCR7 7-dehydrocholesterol reductase 0.663342
NUPL2 nucleoporin like 2 0.663342
MYO6 myosin VI 0.663342
MYOF myoferlin 0.663342
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.663342
RANBP2 RAN binding protein 2 0.663342
NUP153 nucleoporin 153kDa 0.663342
NUP155 nucleoporin 155kDa 0.663342
PPAPDC3 phosphatidic acid phosphatase type 2 domain containing 3 0.663342
CBX3 chromobox homolog 3 0.663342
SEC13 SEC13 homolog (S. cerevisiae) 0.663342
CCND2 cyclin D2 0.663342
EMD emerin 0.663342
NPC1 Niemann-Pick disease, type C1 0.663342
DUX4L6 double homeobox 4 like 6 0.663342
MKL1 megakaryoblastic leukemia (translocation) 1 0.663342
CNEP1R1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 0.663342
NUP107 nucleoporin 107kDa 0.663342
AHRR aryl-hydrocarbon receptor repressor 0.663342
NUP37 nucleoporin 37kDa 0.663342
BCL2 B-cell CLL/lymphoma 2 0.663342
NUP35 nucleoporin 35kDa 0.663342
MCM3AP minichromosome maintenance complex component 3 associated protein 0.663342
GCHFR GTP cyclohydrolase I feedback regulator 0.663342
NUP62 nucleoporin 62kDa 0.663342
SEPHS1 selenophosphate synthetase 1 0.663342
TMEM43 transmembrane protein 43 0.663342
NUP205 nucleoporin 205kDa 0.663342
CDK4 cyclin-dependent kinase 4 0.663342
NRM nurim (nuclear envelope membrane protein) 0.663342
NUP214 nucleoporin 214kDa 0.663342
TMEM18 transmembrane protein 18 0.663342
SMAD3 SMAD family member 3 0.663342
NUP98 nucleoporin 98kDa 0.663342
TXLNG taxilin gamma 0.663342
SMAD1 SMAD family member 1 0.663342
SUMO1 small ubiquitin-like modifier 1 0.663342
NUP93 nucleoporin 93kDa 0.663342
ANXA11 annexin A11 0.663342
SYNE2 spectrin repeat containing, nuclear envelope 2 0.663342
SYNE3 spectrin repeat containing, nuclear envelope family member 3 0.663342
SCRN1 secernin 1 0.663342
TMEM97 transmembrane protein 97 0.663342
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 0.663342
SLC22A18 solute carrier family 22, member 18 0.663342
SEH1L SEH1-like (S. cerevisiae) 0.663342
AHCTF1 AT hook containing transcription factor 1 0.663342
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.663342
NUP160 nucleoporin 160kDa 0.663342
CLIC1 chloride intracellular channel 1 0.663342
SYNE1 spectrin repeat containing, nuclear envelope 1 0.663342
NXT1 nuclear transport factor 2-like export factor 1 0.237908
SNUPN snurportin 1 0.237908
LPIN1 lipin 1 0.237908
ATF6 activating transcription factor 6 0.237908
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.237908
DMPK dystrophia myotonica-protein kinase 0.237908
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.237908
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 0.237908
SENP1 SUMO1/sentrin specific peptidase 1 0.237908
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 0.237908
ZNF224 zinc finger protein 224 0.237908
GUCY2F guanylate cyclase 2F, retinal 0.237908
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.237908
MED7 mediator complex subunit 7 0.237908
KAT8 K(lysine) acetyltransferase 8 0.237908
TOR1A torsin family 1, member A (torsin A) 0.237908
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.237908
TMEM38B transmembrane protein 38B 0.237908
OSBPL3 oxysterol binding protein-like 3 0.237908
OSBPL6 oxysterol binding protein-like 6 0.237908
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.237908
MATR3 matrin 3 0.237908
TSPO translocator protein (18kDa) 0.237908
RANBP1 RAN binding protein 1 0.237908
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.237908
DTX2 deltex 2, E3 ubiquitin ligase 0.237908
GHRHR growth hormone releasing hormone receptor 0.237908
RAE1 ribonucleic acid export 1 0.237908
KPNB1 karyopherin (importin) beta 1 0.237908
NUPL1 nucleoporin like 1 0.237908
NUTF2 nuclear transport factor 2 0.237908
SLC30A1 solute carrier family 30 (zinc transporter), member 1 0.237908
TMEM38A transmembrane protein 38A 0.237908
SP140 SP140 nuclear body protein 0.237908
NUP54 nucleoporin 54kDa 0.237908
PTCHD2 patched domain containing 2 0.237908
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor 0.237908
RECQL5 RecQ protein-like 5 0.237908
FAM156A family with sequence similarity 156, member A 0.237908
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 0.237908
RB1CC1 RB1-inducible coiled-coil 1 0.237908
TUBB tubulin, beta class I 0.237908
KPNA1 karyopherin alpha 1 (importin alpha 5) 0.237908
WDR3 WD repeat domain 3 0.237908
ZC3HC1 zinc finger, C3HC-type containing 1 0.237908
RANGAP1 Ran GTPase activating protein 1 0.237908
AKIRIN1 akirin 1 0.237908
RAP1GAP2 RAP1 GTPase activating protein 2 0.237908
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) 0.237908
TYRO3 TYRO3 protein tyrosine kinase 0.237908
AK9 adenylate kinase 9 0.237908
IPO5 importin 5 0.237908
CEP70 centrosomal protein 70kDa 0.237908
PCM1 pericentriolar material 1 0.237908
PUM2 pumilio RNA-binding family member 2 0.237908
KPNA3 karyopherin alpha 3 (importin alpha 4) 0.237908
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.237908
KPNA5 karyopherin alpha 5 (importin alpha 6) 0.237908
SYNE4 spectrin repeat containing, nuclear envelope family member 4 0.237908
CERS2 ceramide synthase 2 0.237908
CUEDC2 CUE domain containing 2 0.237908
APP amyloid beta (A4) precursor protein 0.237908
POM121 POM121 transmembrane nucleoporin 0.237908
GCOM1 GRINL1A complex locus 1 0.237908
GCH1 GTP cyclohydrolase 1 0.237908
NUP210 nucleoporin 210kDa 0.237908
MRPS23 mitochondrial ribosomal protein S23 0.237908
MRPS14 mitochondrial ribosomal protein S14 0.237908
MRPS15 mitochondrial ribosomal protein S15 0.237908
CBX5 chromobox homolog 5 0.237908
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 0.237908
CEP170 centrosomal protein 170kDa 0.237908
RCC1 regulator of chromosome condensation 1 0.237908
MLIP muscular LMNA-interacting protein 0.237908
CENPT centromere protein T 0.237908
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 0.237908
YBX1 Y box binding protein 1 0.237908
AEN apoptosis enhancing nuclease 0.237908
WHSC1 Wolf-Hirschhorn syndrome candidate 1 0.237908
TMC6 transmembrane channel-like 6 0.237908
TMC8 transmembrane channel-like 8 0.237908
APEH acylaminoacyl-peptide hydrolase 0.237908
CAPG capping protein (actin filament), gelsolin-like 0.237908
FAM76B family with sequence similarity 76, member B 0.237908
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 0.237908
AGFG1 ArfGAP with FG repeats 1 0.237908
RNF6 ring finger protein (C3H2C3 type) 6 0.237908
NUP188 nucleoporin 188kDa 0.237908
GTPBP4 GTP binding protein 4 0.237908
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.237908
DGKH diacylglycerol kinase, eta 0.237908
IPO7 importin 7 0.237908
KLK6 kallikrein-related peptidase 6 0.237908
ANXA4 annexin A4 0.237908
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 0.237908
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.237908
PHF20 PHD finger protein 20 0.237908
CDC14B cell division cycle 14B 0.237908
BRAP BRCA1 associated protein 0.237908
SREBF1 sterol regulatory element binding transcription factor 1 0.237908
HAX1 HCLS1 associated protein X-1 0.237908
DHRS4 dehydrogenase/reductase (SDR family) member 4 0.237908
XPO1 exportin 1 0.237908
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.098109
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6 0.098109
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 0.098109
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 0.098109
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 0.098109
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 0.098109
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A 0.098109
RETSAT retinol saturase (all-trans-retinol 13,14-reductase) 0.098109
MGST2 microsomal glutathione S-transferase 2 0.098109
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.098109
MGST3 microsomal glutathione S-transferase 3 0.098109
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 0.098109
EIF5A2 eukaryotic translation initiation factor 5A2 0.098109
TMEM57 transmembrane protein 57 0.098109
POM121C POM121 transmembrane nucleoporin C 0.098109
MNS1 meiosis-specific nuclear structural 1 0.03318
EDNRA endothelin receptor type A 0.03318
NUP62CL nucleoporin 62kDa C-terminal like 0.03318
FAF1 Fas (TNFRSF6) associated factor 1 0.03318
RRM1 ribonucleotide reductase M1 0.03318
CST3 cystatin C 0.03318
NXF1 nuclear RNA export factor 1 0.03318
KIAA1161 KIAA1161 0.03318
CACYBP calcyclin binding protein 0.03318
LMNTD1 lamin tail domain containing 1 0.03318
FANCL Fanconi anemia, complementation group L 0.03318
BCHE butyrylcholinesterase 0.03318
UNC50 unc-50 homolog (C. elegans) 0.03318
GPX4 glutathione peroxidase 4 0.03318
DPY19L2 dpy-19-like 2 (C. elegans) 0.03318
GMCL1 germ cell-less, spermatogenesis associated 1 0.03318
NDEL1 nudE neurodevelopment protein 1-like 1 0.03318
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 0.03318
SHISA5 shisa family member 5 0.03318
REPIN1 replication initiator 1 0.03318
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.03318
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.03318
ANXA7 annexin A7 0.03318
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.03318
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 0.03318
EDNRB endothelin receptor type B 0.03318
HRASLS HRAS-like suppressor 0.03318
PRKCZ protein kinase C, zeta 0.03318
TMEM201 transmembrane protein 201 0.03318
ENY2 enhancer of yellow 2 homolog (Drosophila) 0.03318
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.03318
IGF2R insulin-like growth factor 2 receptor 0.03318
CMTM3 CKLF-like MARVEL transmembrane domain containing 3 0.03318
CYHR1 cysteine/histidine-rich 1 0.03318
NUCB2 nucleobindin 2 0.03318
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 0.03318
OSBPL8 oxysterol binding protein-like 8 0.03318
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 0.03318
SUN3 Sad1 and UNC84 domain containing 3 0.03318
ERN1 endoplasmic reticulum to nucleus signaling 1 0.03318
PTGES prostaglandin E synthase 0.03318
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.03318
NAV3 neuron navigator 3 0.03318
CLGN calmegin 0.03318