notch signaling pathway Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. (Gene Ontology, GO_0007219)
External Link http://amigo.geneontology.org/amigo/term/GO:0007219
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Genes

130 genes participating in the notch signaling pathway biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ADAM10 ADAM metallopeptidase domain 10
ADAM17 ADAM metallopeptidase domain 17
AGO1 argonaute RISC catalytic component 1
AGO2 argonaute RISC catalytic component 2
AGO3 argonaute RISC catalytic component 3
AGO4 argonaute RISC catalytic component 4
APH1A APH1A gamma secretase subunit
APH1B APH1B gamma secretase subunit
APP amyloid beta (A4) precursor protein
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ASCL1 achaete-scute family bHLH transcription factor 1
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BMP2 bone morphogenetic protein 2
CCNC cyclin C
CCND1 cyclin D1
CDK6 cyclin-dependent kinase 6
CDK8 cyclin-dependent kinase 8
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CNTN1 contactin 1
CNTN6 contactin 6
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
CUL1 cullin 1
DLK1 delta-like 1 homolog (Drosophila)
DLL1 delta-like 1 (Drosophila)
DLL3 delta-like 3 (Drosophila)
DLL4 delta-like 4 (Drosophila)
DNER delta/notch-like EGF repeat containing
DTX1 deltex 1, E3 ubiquitin ligase
DTX2 deltex 2, E3 ubiquitin ligase
DTX3 deltex 3, E3 ubiquitin ligase
DTX4 deltex 4, E3 ubiquitin ligase
E2F1 E2F transcription factor 1
E2F3 E2F transcription factor 3
EP300 E1A binding protein p300
EPN1 epsin 1
EPN2 epsin 2
ETV2 ets variant 2
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FOXC1 forkhead box C1
FOXC2 forkhead box C2
FURIN furin (paired basic amino acid cleaving enzyme)
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GMDS GDP-mannose 4,6-dehydratase
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HDAC1 histone deacetylase 1
HDAC10 histone deacetylase 10
HDAC3 histone deacetylase 3
HDAC5 histone deacetylase 5
HDAC7 histone deacetylase 7
HDAC9 histone deacetylase 9
HES1 hes family bHLH transcription factor 1
HES5 hes family bHLH transcription factor 5
HES7 hes family bHLH transcription factor 7
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HOXD3 homeobox D3
IFT172 intraflagellar transport 172
IFT74 intraflagellar transport 74
IFT88 intraflagellar transport 88
IL2RA interleukin 2 receptor, alpha
ITCH itchy E3 ubiquitin protein ligase
ITGB1BP1 integrin beta 1 binding protein 1
JAG1 jagged 1
JAG2 jagged 2
KAT2B K(lysine) acetyltransferase 2B
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MAML1 mastermind-like 1 (Drosophila)
MAML2 mastermind-like 2 (Drosophila)
MAML3 mastermind-like 3 (Drosophila)
MDK midkine (neurite growth-promoting factor 2)
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2
MIB1 mindbomb E3 ubiquitin protein ligase 1
MIB2 mindbomb E3 ubiquitin protein ligase 2
MOV10 Mov10 RISC complex RNA helicase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NCSTN nicastrin
NEURL1 neuralized E3 ubiquitin protein ligase 1
NEURL1B neuralized E3 ubiquitin protein ligase 1B
NEUROD4 neuronal differentiation 4
NKAP NFKB activating protein
NLE1 notchless homolog 1 (Drosophila)
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH3 notch 3
NOTCH4 notch 4
NUMB numb homolog (Drosophila)
POFUT1 protein O-fucosyltransferase 1
POGLUT1 protein O-glucosyltransferase 1
PSEN1 presenilin 1
PSEN2 presenilin 2
PSENEN presenilin enhancer gamma secretase subunit
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RBX1 ring-box 1, E3 ubiquitin protein ligase
RIPPLY1 ripply transcriptional repressor 1
RIPPLY2 ripply transcriptional repressor 2
RITA1 RBPJ interacting and tubulin associated 1
RPS27A ribosomal protein S27a
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SKP1 S-phase kinase-associated protein 1
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SNW1 SNW domain containing 1
SPEN spen family transcriptional repressor
TBL1X transducin (beta)-like 1X-linked
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TFDP1 transcription factor Dp-1
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLE2 transducin-like enhancer of split 2
TLE3 transducin-like enhancer of split 3
TLE4 transducin-like enhancer of split 4
TMEM100 transmembrane protein 100
TNRC6A trinucleotide repeat containing 6A
TNRC6B trinucleotide repeat containing 6B
TNRC6C trinucleotide repeat containing 6C
TP53 tumor protein p53
TP63 tumor protein p63
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
WDR12 WD repeat domain 12
ZNF423 zinc finger protein 423