nordihydroguaiaretic acid-6942 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the nordihydroguaiaretic acid-6942 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACTL8 actin-like 8
ADAM23 ADAM metallopeptidase domain 23
ANG angiogenin, ribonuclease, RNase A family, 5
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARNT aryl hydrocarbon receptor nuclear translocator
BAIAP3 BAI1-associated protein 3
C14ORF93 chromosome 14 open reading frame 93
CCNO cyclin O
CD6 CD6 molecule
CD8A CD8a molecule
CDC14B cell division cycle 14B
CFHR4 complement factor H-related 4
CLSTN2 calsyntenin 2
CORO7 coronin 7
CSF1 colony stimulating factor 1 (macrophage)
CTBS chitobiase, di-N-acetyl-
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DOHH deoxyhypusine hydroxylase/monooxygenase
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EPHA2 EPH receptor A2
FADS3 fatty acid desaturase 3
FAS Fas cell surface death receptor
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGF4 fibroblast growth factor 4
FILIP1L filamin A interacting protein 1-like
GRIP2 glutamate receptor interacting protein 2
GTPBP4 GTP binding protein 4
HMOX1 heme oxygenase 1
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HR hair growth associated
HRK harakiri, BCL2 interacting protein
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IFI6 interferon, alpha-inducible protein 6
IGFBP3 insulin-like growth factor binding protein 3
IL15RA interleukin 15 receptor, alpha
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRF9 interferon regulatory factor 9
ITGA10 integrin, alpha 10
JMJD4 jumonji domain containing 4
KLF2 Kruppel-like factor 2
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LPIN1 lipin 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MALT1 MALT1 paracaspase
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP9 microtubule-associated protein 9
MBNL3 muscleblind-like splicing regulator 3
MECP2 methyl CpG binding protein 2
MEF2D myocyte enhancer factor 2D
MMP14 matrix metallopeptidase 14 (membrane-inserted)
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NFYA nuclear transcription factor Y, alpha
NR2E3 nuclear receptor subfamily 2, group E, member 3
NREP neuronal regeneration related protein
NUPR1 nuclear protein, transcriptional regulator, 1
PARD6B par-6 family cell polarity regulator beta
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PGAP3 post-GPI attachment to proteins 3
PIAS4 protein inhibitor of activated STAT, 4
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PRLR prolactin receptor
PROSC proline synthetase co-transcribed homolog (bacterial)
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RAB6A RAB6A, member RAS oncogene family
RAD52 RAD52 homolog (S. cerevisiae)
RNF24 ring finger protein 24
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SIPA1L3 signal-induced proliferation-associated 1 like 3
SIX2 SIX homeobox 2
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SOX10 SRY (sex determining region Y)-box 10
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN1 spectrin, beta, non-erythrocytic 1
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STRN3 striatin, calmodulin binding protein 3
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TOX4 TOX high mobility group box family member 4
TRIM21 tripartite motif containing 21
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TSPAN1 tetraspanin 1
TSPAN3 tetraspanin 3
TTC38 tetratricopeptide repeat domain 38
USB1 U6 snRNA biogenesis 1
VEZT vezatin, adherens junctions transmembrane protein
WLS wntless Wnt ligand secretion mediator
XAF1 XIAP associated factor 1
YLPM1 YLP motif containing 1
ZER1 zyg-11 related, cell cycle regulator
ZNF10 zinc finger protein 10
ZNF280A zinc finger protein 280A
ZSCAN26 zinc finger and SCAN domain containing 26

decreased expression

Symbol Name
ANXA1 annexin A1
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARMC6 armadillo repeat containing 6
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BPGM 2,3-bisphosphoglycerate mutase
C19ORF24 chromosome 19 open reading frame 24
C4ORF29 chromosome 4 open reading frame 29
C7ORF43 chromosome 7 open reading frame 43
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC88C coiled-coil domain containing 88C
CCNE1 cyclin E1
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEP72 centrosomal protein 72kDa
CLDN4 claudin 4
CLK1 CDC-like kinase 1
CNKSR1 connector enhancer of kinase suppressor of Ras 1
DBR1 debranching RNA lariats 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DSCAM Down syndrome cell adhesion molecule
ECHDC2 enoyl CoA hydratase domain containing 2
EDC4 enhancer of mRNA decapping 4
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM155B family with sequence similarity 155, member B
FANCE Fanconi anemia, complementation group E
FBXL15 F-box and leucine-rich repeat protein 15
FOXJ2 forkhead box J2
GLTSCR1 glioma tumor suppressor candidate region gene 1
GMIP GEM interacting protein
GRAMD3 GRAM domain containing 3
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HAUS6 HAUS augmin-like complex, subunit 6
HIST1H2AE histone cluster 1, H2ae
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
INSIG2 insulin induced gene 2
IRAK4 interleukin-1 receptor-associated kinase 4
KAT2B K(lysine) acetyltransferase 2B
KIF20B kinesin family member 20B
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LINC00115 long intergenic non-protein coding RNA 115
LMCD1 LIM and cysteine-rich domains 1
LOC100272216 uncharacterized LOC100272216
LRRC16A leucine rich repeat containing 16A
LY6D lymphocyte antigen 6 complex, locus D
MAN2C1 mannosidase, alpha, class 2C, member 1
MEIS2 Meis homeobox 2
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MSX1 msh homeobox 1
MTCL1 microtubule crosslinking factor 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYBBP1A MYB binding protein (P160) 1a
NCAPH non-SMC condensin I complex, subunit H
NRGN neurogranin (protein kinase C substrate, RC3)
PANK4 pantothenate kinase 4
PDZRN3 PDZ domain containing ring finger 3
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PISD phosphatidylserine decarboxylase
PMM1 phosphomannomutase 1
PNPLA6 patatin-like phospholipase domain containing 6
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RABL6 RAB, member RAS oncogene family-like 6
RANGRF RAN guanine nucleotide release factor
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RNF2 ring finger protein 2
RPL23AP7 ribosomal protein L23a pseudogene 7
RPUSD2 RNA pseudouridylate synthase domain containing 2
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCN1B sodium channel, voltage gated, type I beta subunit
SETD8 SET domain containing (lysine methyltransferase) 8
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
SNIP1 Smad nuclear interacting protein 1
SOWAHC sosondowah ankyrin repeat domain family member C
SPIDR scaffolding protein involved in DNA repair
SREK1IP1 SREK1-interacting protein 1
STAG3L1 stromal antigen 3-like 1 (pseudogene)
TBC1D17 TBC1 domain family, member 17
TGFBI transforming growth factor, beta-induced, 68kDa
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM104 transmembrane protein 104
TMEM2 transmembrane protein 2
TP53BP2 tumor protein p53 binding protein 2
TRIM5 tripartite motif containing 5
TUBA3C tubulin, alpha 3c
USP36 ubiquitin specific peptidase 36
VASH2 vasohibin 2
ZNF226 zinc finger protein 226
ZNF552 zinc finger protein 552
ZNF668 zinc finger protein 668
ZNF767P zinc finger family member 767, pseudogene